{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:28:02Z","timestamp":1786739282471,"version":"build-2736575974"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Kimura's disease was first described by Kimura and Sceto in China in 1937. Kimura disease is a chronic inflammatory disorder of idiopathic etiology. The clinical presentation of Kimura's disease is painless solitary or multiple subcutaneous nodules, asymmetric, mostly in the head and neck region with often association with lymphadenopathy. Typically, the nodules are found on preauricular, submandibular, and popliteal regions as well as oral cavity, larynx, and parotid glands. In the present report, we describe a case of a 27-year-old male presented to our hospital with history of right neck and lip swelling for 10 days. In the history, the patient mentioned that he had bloody diarrhea four to six times day and he lost 10 kg in 1 month. The specimen was sent for histopathological examination which showed the lymph node architecture is preserved with significant increase number of eosinophils which is consistent with Kimura's disease. There is no agreement on the management aspects in Kimura's disease so far. The primary treatment for Kimura's disease includes surgical resection. Additional medical therapy including regional or systemic steroid therapy, cytotoxic therapy, and radiation has also been utilized. Considered as an inflammatory process, the disease has an excellent prognosis, although it may recur locally and wax and wane over time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_373_19","type":"journal-article","created":{"date-parts":[[2019,10,1]],"date-time":"2019-10-01T00:49:11Z","timestamp":1569890951000},"page":"3028-3031","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":14,"title":["Mepolizumab as an effective treatment for Kimura's disease associated with ulcerative colitis"],"prefix":"10.4103","volume":"8","author":[{"given":"Faisal","family":"Al Shammari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman","family":"Nasiri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Alkhathami","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahad","family":"Alawfi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammed","family":"Alfifi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eqab","family":"Al Otaibi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-51-20260203","first-page":"326","article-title":"A rare case of inguinal kimura disease","volume":"73","author":"Gregory","year":"2018","journal-title":"Med J 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Pathol"},{"key":"R5-51-20260203","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.anorl.2016.12.001","article-title":"Kimura's disease in a 50-year-old Tunisian man","volume":"134","author":"Drouillard","year":"2017","journal-title":"Eur Ann Otorhinolaryngol Head Neck Dis"},{"key":"R6-51-20260203","doi-asserted-by":"crossref","first-page":"158","DOI":"10.3329\/bjms.v17i1.35299","article-title":"A case of Angiolymphoid hyperplasia with eosinophilia in proximal ascending colon mimicking colon carcinoma","volume":"17","author":"Sanjushree","year":"2018","journal-title":"Bangladesh Journal of Medical Science"},{"key":"R7-51-20260203","first-page":"415865","article-title":"Kimura's Disease in a Caucasian Female: A Very Rare Cause of Lymphadenopathy","volume":"2014","author":"Osuch-W\u00f3jcikiewicz","year":"2014","journal-title":"Case Rep Otolaryngol"},{"key":"R8-51-20260203","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1001\/archopht.122.6.917","article-title":"Bilateral lacrimal gland involvement with Kimura disease in an African American male","volume":"122","author":"Yoganathan","year":"2004","journal-title":"Arch Ophthalmol"},{"key":"R9-51-20260203","first-page":"88","article-title":"Kimura's disease: A rare cause of nephrotic syndrome with lymphadenopathy","volume":"18","author":"Othman","year":"2011","journal-title":"Malays J Med Sci"},{"key":"R10-51-20260203","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1016\/S0196-0709(96)90088-5","article-title":"Angiolymphoid hyperplasia with eosinophilia and vascular tumors of the head and neck","volume":"17","author":"Don","year":"1996","journal-title":"Am J Otolaryngol"},{"key":"R12-51-20260203","first-page":"21414","article-title":"Kimura's disease: Risk factors of recurrence and prognosis","volume":"8","author":"Chen","year":"2015","journal-title":"Int J Clin Exp Med"},{"key":"R13-51-20260203","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1097\/SCS.0000000000002595","article-title":"Kimura disease presenting as forehead soft mass","volume":"27","author":"Choi","year":"2016","journal-title":"J Craniofac Surg"},{"key":"R14-51-20260203","doi-asserted-by":"crossref","first-page":"668","DOI":"10.1111\/j.1445-5994.2008.01711.x","article-title":"Kimura disease: Review of the literature","volume":"38","author":"Sun","year":"2008","journal-title":"Intern Med J"},{"key":"R15-51-20260203","doi-asserted-by":"crossref","first-page":"232","DOI":"10.4103\/0970-9371.190453","article-title":"Kimura's disease: A diagnostic challenge experienced with cytology of postauricular swelling with histopathological relevance","volume":"33","author":"Sherpa","year":"2016","journal-title":"J Cytol"},{"key":"R16-51-20260203","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1007\/BF02779234","article-title":"Kimura's disease (angiolymphoid hyperplasia with eosinophilia) associated with ulcerative colitis","volume":"28","author":"Shimamoto","year":"1993","journal-title":"Gastroenterol Jpn"},{"key":"R17-51-20260203","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1016\/j.ijom.2016.08.013","article-title":"Comparison of the efficacy of different treatment modalities for Kimura's disease","volume":"46","author":"Ye","year":"2017","journal-title":"Int J Oral Maxillofac Surg"},{"key":"R18-51-20260203","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1111\/j.1365-4632.2004.02527.x","article-title":"Kimura's disease in a Caucasian male treated with cyclosporine","volume":"44","author":"Birol","year":"2005","journal-title":"Int J Dermatol"},{"key":"R19-51-20260203","first-page":"2219","article-title":"Successful treatment of Kimura's disease with leflunomide and methylprednisolone: A case report","volume":"7","author":"Ma","year":"2014","journal-title":"Int J Clin Exp Med"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_373_19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:27:33Z","timestamp":1786735653000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_373_19"}},"subtitle":["A case report"],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":18,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_373_19","relation":{},"ISSN":["2249-4863"],"issn-type":[{"value":"2249-4863","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]}}}