{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T01:09:16Z","timestamp":1790903356289,"version":"4.1.0"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"10","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n Worldwide, one million cases of bacterial meningitis are estimated to occur and 200,000 of them die annually. Case fatality rates vary with age at the time of illness and the species of bacterium causing infection. In view of variable clinical features and complication rates in various studies, the present study was planned to assess the clinical and laboratory profile of patients with acute bacterial meningitis and analyze the therapeutic response and short-term sequelae.<\/jats:p>\n <\/jats:sec>\n \n Materials:<\/jats:title>\n This study was conducted in the department of pediatrics at Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak. A total of 50 pediatric patients with signs and symptoms of acute bacterial meningitis who satisfied the inclusion or selection criteria were enrolled in the study. Appropriate statistical tests were applied for analysis and trial registry was done with PGIMS.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n In the present study, slightly more males (54%) were found than females (46%). The sequelae and mortality were 33.3%, 26.1% and 7.4%, 8.7% in males and females, respectively. There were higher chances of sequelae or mortality in males as compared to females (OR 1.289, 95% CI 0.073\u20136.11,\n P<\/jats:italic>\n > 0.05). Predominant cells were polymorphonuclear (PMN) cells except in >120 months age group where both PMN (50%) and mononuclear (50%) cells were equally visualized. Mean CSF protein was slightly higher in 2\u201324 months age group.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n We compared the group with sequelae with the group with no sequelae and found neurological deficit (\n P<\/jats:italic>\n < 0.01), and presence of complications (\n P<\/jats:italic>\n < 0.01) were significantly associated with sequelae.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_429_22","type":"journal-article","created":{"date-parts":[[2022,11,9]],"date-time":"2022-11-09T05:53:22Z","timestamp":1667973202000},"page":"6274-6279","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Clinical and laboratory profile of patients with presumptive clinical diagnosis of acute bacterial meningitis and its short-term complications"],"prefix":"10.4103","volume":"11","author":[{"given":"Anubha","family":"Garg","sequence":"first","affiliation":[{"name":"Department of Medicine, Pt. BD Sharma, PGIMS, Rohtak, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Fotedar","sequence":"additional","affiliation":[{"name":"Department of Medicine, Pt. BD Sharma, PGIMS, Rohtak, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Bharti","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh","family":"Garg","sequence":"additional","affiliation":[{"name":"ASMO, HCMS, Government of Haryana, Rohtak, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anupama","family":"Sharma","sequence":"additional","affiliation":[{"name":"Private Practitioner, Paediatrics, Rohtak, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumit","family":"Chawla","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Shri Atal Bihari Vajpayee Government Medical College, Faridabad, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,10,31]]},"reference":[{"key":"R1-20260527","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/S0031-3955(16)36190-9","article-title":"Bacterial meningitis:Diagnosis and initial antibiotic therapy","volume":"34","author":"Dagbjartsson","year":"1987","journal-title":"Pediatr Clin N Am"},{"key":"R2-20260527","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/BF02750932","article-title":"Bacterial meningitis in India-An IJP survey","volume":"58","author":"Kabra","year":"1991","journal-title":"Ind J Pediatr"},{"key":"R3-20260527","doi-asserted-by":"crossref","first-page":"719","DOI":"10.4067\/S0034-98872001000700003","article-title":"Trends of etiology of acute bacterial meningitis in Chilean children from 1989 to 1998. 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