{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:38:12Z","timestamp":1787841492879,"version":"build-2784847793"},"reference-count":15,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,8]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n During the coronavirus disease 2019 (COVD-19) pandemic, the incidence of mucormycosis also increased, especially affecting individuals who have had the COVID-19 infection in the past.<\/jats:p>\n <\/jats:sec>\n \n Aims:<\/jats:title>\n The aim of the study is to assess risk factors and clinical and histopathological features of mucormycosis in post-COVID-19 cases.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n This is a retrospective study conducted in a tertiary care COVID-19-dedicated hospital, Dehradun, Uttarakhand, India, over a period of 2 months during the COVID-19 pandemic. All surgical specimens submitted for histopathology with a suspected diagnosis of mucormycosis were included. Histopathology was considered the gold standard. All histopathologically confirmed cases were studied in detail with respect to histopathology, clinico-radiological features, and microbiological results<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Of 25 cases with clinical diagnosis of mucormycosis, nine were histopathologically confirmed as mucormycosis. Seven patients had diabetes, while two did not have any co-morbidity. The fungal load was heavy in 50% cases, and the proportion of necrosis was higher with diabetes mellitus, as compared to non-diabetic and non-co-morbidity patients. Angioinvasion (33.3% cases), soft-tissue invasion (44.4%), Splendor\u2013Hoeppli phenomenon (44.4%), and neural invasion (11.1%) were also present. Mixed infection (Mucormycosis and Aspergillus species) was present in three of the cases who also had diabetes. The microbiological investigations were positive in only 55.5% cases.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Post-COVID Mucormycosis has fatal outcomes. Early diagnosis and treatment are the key to successful treatment. Early and reliable diagnosis can be offered by histopathological examination.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_42_24","type":"journal-article","created":{"date-parts":[[2024,7,26]],"date-time":"2024-07-26T02:02:38Z","timestamp":1721959358000},"page":"3257-3263","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Rhinocerebral mucormycosis: A clinicopathological analysis of COVID-19-associated mucormycosis"],"prefix":"10.4103","volume":"13","author":[{"given":"Neelima","family":"Bahal","sequence":"first","affiliation":[{"name":"Department of Pathology, Government Doon Medical College, Dehradun, Uttarakhand, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AR","family":"Piyush","sequence":"additional","affiliation":[{"name":"Department of Pathology, Government Doon Medical College, Dehradun, Uttarakhand, 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