{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:24:33Z","timestamp":1787757873617,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>A 17-year-old male with uneventful previous history developed generalized myalgias, exercise intolerance, and general fatigue after two dosages of azithromycin (500 mg\/d) during 3 d for febrile infection. Neurologic exam revealed generally reduced tendon reflexes. Serum creatine kinase (CK) was elevated to 25000 U\/L. Needle-EMG showed short and small, polyphasic motor-units and abnormal spontaneous activity, being interpreted as myositis. Azithromycin was discontinued and he was advised to avoid the fitness studio and to drink plenty of liquids. Myalgias disappeared within two days and CK continuously declined. Azithromycin may trigger rhabdomyolysis in the context of exercise and infection. Azithromycin may be myotoxic and should be prescribed with caution in exercising and infected patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_452_21","type":"journal-article","created":{"date-parts":[[2022,5,25]],"date-time":"2022-05-25T07:41:10Z","timestamp":1653464470000},"page":"2211-2213","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Rhabdomyolysis triggered by azithromycin"],"prefix":"10.4103","volume":"11","author":[{"given":"Josef","family":"Finsterer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia C","family":"Stollberger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madleine","family":"Melichart-Kotig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-99-20240828","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/s00467-009-1223-9","article-title":"Rhabdomyolysis: A review, with emphasis on the pediatric population","volume":"25","author":"Elsayed","year":"2010","journal-title":"Pediatr Nephrol"},{"key":"R2-99-20240828","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1186\/1471-2431-13-134","article-title":"Clinical spectrum of rhabdomyolysis presented to pediatric emergency department","volume":"13","author":"Chen","year":"2013","journal-title":"BMC Pediatr"},{"key":"R3-99-20240828","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1097\/RHU.0000000000000192","article-title":"Clarithromycin-associated rhabdomyolysis in an infant","volume":"20","author":"Mustafa","year":"2014","journal-title":"J Clin Rheumatol"},{"key":"R4-99-20240828","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.ijscr.2016.07.007","article-title":"Pregabalin- and azithromycin-induced rhabdomyolysis with purpura: An unrecognized interaction: A case report","volume":"26","author":"Kato","year":"2016","journal-title":"Int J Surg Case Rep"},{"key":"R5-99-20240828","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/RHU.0b013e3182056042","article-title":"Colchicine-induced rhabdomyolysis in a heart\/lung transplant patient with concurrent use of cyclosporin, pravastatin, and azithromycin","volume":"17","author":"Bouqui\u00e9","year":"2011","journal-title":"J Clin Rheumatol"},{"key":"R6-99-20240828","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1503\/cmaj.140950","article-title":"Risk of adverse events among older adults following co-prescription of clarithromycin and statins not metabolized by cytochrome P450 3A4","volume":"187","author":"Li","year":"2015","journal-title":"CMAJ"},{"key":"R7-99-20240828","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1177\/0883073813485132","article-title":"Rhabdomyolysis associated with human parvovirus B19 infection in a patient with Fukuyama-type congenital muscular dystrophy","volume":"29","author":"Ishikawa","year":"2014","journal-title":"J Child Neurol"},{"key":"R8-99-20240828","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1179\/1465328110Y.0000000005","article-title":"Exertional rhabdomyolysis after influenza A (H3N2) infection in a basketball player boy","volume":"31","author":"Sevketoglu","year":"2011","journal-title":"Ann Trop Paediatr"},{"key":"R9-99-20240828","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.jbspin.2019.01.018","article-title":"Statins, myalgia, and rhabdomyolysis","volume":"87","author":"Tournadre","year":"2020","journal-title":"Joint Bone Spine"},{"key":"R10-99-20240828","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1007\/s13730-019-00392-6","article-title":"Novel Asp511Thr mutation in McArdle disease with acute kidney injury caused by rhabdomyolysis","volume":"8","author":"Satoh","year":"2019","journal-title":"CEN Case Rep"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_452_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:56:12Z","timestamp":1787756172000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_452_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_452_21","relation":{"has-preprint":[{"id-type":"doi","id":"10.22541\/au.170665552.22477691\/v1","asserted-by":"object"}]},"ISSN":["2249-4863"],"issn-type":[{"value":"2249-4863","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}