{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:23:19Z","timestamp":1787757799495,"version":"build-2784847793"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Tuberculosis (TB) has historically been declared cured at the point of microbiological clearance. Yet emerging evidence from systematic reviews and cohort studies demonstrates that between 30% and 80% of pulmonary TB survivors experience persistent symptoms, organ damage or functional impairment after treatment completion; a burden that existing outcome metrics fail to capture. We propose the term Long TB, with the formal designation Post-Acute Sequelae of Tuberculosis (PAST-TB), as a conceptual and clinical framework to define, study and address this under-recognised morbidity. Drawing explicit parallels with Long COVID (post-acute sequelae of SARS-CoV-2 or PASC), we argue that the Long TB framing is not merely rhetorical but scientifically grounded, strategically powerful and urgently needed. With approximately 155 million TB survivors alive globally and modelling studies attributing up to 47% of TB-related disability-adjusted life years (DALYs) to the post-treatment period, the case for a systematic post-TB care agenda, anchored by this new terminology is compelling. We attempt to outline the multi-system domains of Long TB, its shared pathological drivers with PASC and the programmatic and research reforms required to move from bacteriological to biological cure as the standard of care.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_514_26","type":"journal-article","created":{"date-parts":[[2026,5,23]],"date-time":"2026-05-23T14:00:13Z","timestamp":1779544813000},"page":"1463-1466","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Long TB: Framing post-acute sequelae of tuberculosis as a distinct clinical entity"],"prefix":"10.4103","volume":"15","author":[{"given":"Sunil Kumar","family":"Raina","sequence":"first","affiliation":[{"name":"Department of Community Medicine, Dr. RP Govt. Medical College, Tanda, Himachal Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raman","family":"Kumar","sequence":"additional","affiliation":[{"name":"Consultant Family Medicine, Greater Noida, Editor in Chief Journal of Family Medicine and Primary Care, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,5,23]]},"reference":[{"key":"R2-20260603","doi-asserted-by":"crossref","first-page":"e0000805","DOI":"10.1371\/journal.pgph.0000805","article-title":"Magnitude and factors associated with post-tuberculosis lung disease in low- and middle-income countries:A systematic review and meta-analysis","volume":"2","author":"Maleche-Obimbo","year":"2022","journal-title":"PLOS Glob Public Health"},{"key":"R3-20260603","doi-asserted-by":"crossref","first-page":"e1020","DOI":"10.1016\/S2214-109X(25)00105-6","article-title":"Post-pulmonary tuberculosis lung function:A systematic review and meta-analysis","volume":"13","author":"Ratnakumar","year":"2025","journal-title":"Lancet Glob Health"},{"key":"R4-20260603","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/s15010-025-02645-2","article-title":"Post-tuberculosis lung disease:A guide for clinicians","volume":"54","author":"Fumagalli","year":"2026","journal-title":"Infection"},{"key":"R5-20260603","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1186\/s12890-019-0966-8","article-title":"Treatment outcomes of tuberculous meningitis in adults:A systematic review and meta-analysis","volume":"19","author":"Wang","year":"2019","journal-title":"BMC Pulm Med"},{"key":"R6-20260603","doi-asserted-by":"crossref","first-page":"e1679","DOI":"10.1016\/S2214-109X(21)00367-3","article-title":"Lifetime burden of disease due to incident tuberculosis:A global reappraisal including post-tuberculosis sequelae","volume":"9","author":"Menzies","year":"2021","journal-title":"Lancet Glob Health"},{"issue":"34","key":"R7-20260603","doi-asserted-by":"crossref","first-page":"250148","DOI":"10.1183\/16000617.0148-2025","article-title":"Post-tuberculosis morbidities and their associated mortality:Moving from challenges to solutions","volume":"22","author":"Wang","year":"2025","journal-title":"Eur Respir Rev"},{"key":"R9-20260603","doi-asserted-by":"crossref","first-page":"e941595","DOI":"10.12659\/MSM.941595","article-title":"Editorial:Post-Acute Sequelae of SARS-CoV-2 Infection (PASC). Updated terminology for the long-term effects of COVID-19","volume":"29","author":"Parums","year":"2023","journal-title":"Med Sci Monit"},{"key":"R10-20260603","doi-asserted-by":"crossref","first-page":"1564","DOI":"10.1038\/s41591-024-02987-8","article-title":"Three-year outcomes of post-acute sequelae of COVID-19","volume":"30","author":"Cai","year":"2024","journal-title":"Nat Med"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_514_26","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T14:53:53Z","timestamp":1787756033000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_514_26"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":8,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_514_26","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"2026-03-19","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-20","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}