{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:38:01Z","timestamp":1786653481003,"version":"build-2736575974"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">Streptococcus pneumoniae<\/jats:italic>\n                    is a rare cause of appendicitis, skin soft tissue, and bloodstream infections. The clinical significance of its isolation from samples of skin or soft tissues and pus from the appendix is poorly understood. Invasive pneumococcal disease (IPD) continues to be a problem in India, associated with a high case fatality rate despite treatment facilities available in the hospital settings. In the present study, we report three adult cases, one presented as acute appendicitis, the other had skin and soft tissue infection, and third presented with bloodstream infection caused by\n                    <jats:italic toggle=\"yes\">Streptococcus pneumoniae<\/jats:italic>\n                    from our level 1 trauma center. The patients with acute appendicitis and soft tissue infection recovered when treated with appropriate antimicrobial therapy, however, the one with pneumococcal sepsis could not be revived.\n                  <\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_529_20","type":"journal-article","created":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T08:49:53Z","timestamp":1601196593000},"page":"5058-5061","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Atypical case presentations of Streptococcus pneumoniae from level 1 trauma centre in India -A case series"],"prefix":"10.4103","volume":"9","author":[{"given":"Aishwarya","family":"Govindaswamy","sequence":"first","affiliation":[{"name":"Department of Microbiology, KMCH Institute of Health Sciences and Research, Coimbatore, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sushma","family":"Sagar","sequence":"additional","affiliation":[{"name":"Department of Trauma and Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek","family":"Trikha","sequence":"additional","affiliation":[{"name":"Orthopedics, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samarth","family":"Mittal","sequence":"additional","affiliation":[{"name":"Orthopedics, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Orthopedics, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Purva","family":"Mathur","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Jai Prakash Narayan Apex Trauma Centre, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020,9]]},"reference":[{"key":"R1-20260813","doi-asserted-by":"crossref","first-page":"12S","DOI":"10.1016\/S0002-9343(99)00103-5","article-title":"Unusual manifestations of invasive pneumococcal infection","volume":"107","author":"Taylor","year":"1999","journal-title":"Am J Med"},{"key":"R2-20260813","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1093\/clinids\/22.6.993","article-title":"Tuboovarian abscess and peritonitis caused by Streptococcus pneumoniae serotype 1 in young girls","volume":"22","author":"Sirotnak","year":"1996","journal-title":"Clin Infect Dis Off Publ Infect Dis Soc 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prognosis","volume":"7","author":"Burman","year":"1985","journal-title":"Rev Infect Dis"},{"key":"R16-20260813","first-page":"216","article-title":"Pneumococcal disease burden from an Indian perspective: Need for its prevention in pulmonology practice","volume":"36","author":"Koul","year":"2019","journal-title":"Lung India Off Organ Indian Chest Soc"}],"container-title":["Journal of Family Medicine and Primary 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