{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:34:49Z","timestamp":1787070889343,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Systemic lupus erythematosus (SLE) is the prototype of an autoimmune disease with various manifestations in the skin and several other organs. Subacute cutaneous lupus erythematosus may present with annular and psoriasiform lesions. There have been case reports of pustular lesions in SLE. Herein, we describe a known case of SLE, who developed pustular and crusted lesions which complicated the course of the disease. We considered Acute Generalised Exanthematous Pustulosis, Subcorneal Pustular Dermatosis, Pustular Psoriasis, Pustular Vasculitis, and Pustular Folliculitis as our initial differential diagnosis. A potassium hydroxide mount from crusted lesions showed scabies mites. With these findings, a diagnosis of SLE complicated with crusted scabies was made. She was managed with multiple systemic immunosuppressant and antiscabetic measures following which clinical improvement was seen with remission of her lesions.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_569_24","type":"journal-article","created":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T04:01:35Z","timestamp":1731729695000},"page":"5374-5377","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Pustular and crusted lesions in systemic lupus erythematosus: A case report"],"prefix":"10.4103","volume":"13","author":[{"given":"Allam P.","family":"Reddy","sequence":"first","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy, SRM Medical College and Research Centre, Chengalpattu, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramachandran","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy, SRM Medical College and Research Centre, Chengalpattu, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murali","family":"Narasimhan","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Venereology and Leprosy, SRM Medical College and Research Centre, Chengalpattu, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"R1-20250129","doi-asserted-by":"crossref","first-page":"e7475","DOI":"10.1002\/ccr3.7475","article-title":"Annular pustular crusted plaques as unusual cutaneous presentation of systemic lupus erythematosus","volume":"11","author":"Gheisari","year":"2023","journal-title":"Clin Case Rep"},{"key":"R3-20250129","doi-asserted-by":"crossref","first-page":"1904","DOI":"10.1038\/jid.2013.44","article-title":"Rare variations in IL36RN in severe adverse drug reactions manifesting as acute generalized exanthematous pustulosis","volume":"133","author":"Navarini","year":"2013","journal-title":"J Investig Dermatol"},{"key":"R4-20250129","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1016\/j.ijwd.2020.02.003","article-title":"SPD:Comprehensive review and report of a case presenting during pregnancy","volume":"6","author":"Bhargava","year":"2020","journal-title":"Int J Women's Dermatol"},{"key":"R5-20250129","doi-asserted-by":"crossref","first-page":"e66","DOI":"10.1111\/ijd.14332","article-title":"Generalized pustular psoriasis complicated with bullous pemphigoid","volume":"58","author":"Tsuchida","year":"2019","journal-title":"Int J Dermatol"},{"key":"R6-20250129","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1111\/exd.13699","article-title":"Generalized pustular psoriasis - A model disease for specific targeted immunotherapy, systematic review","volume":"27","author":"Boehner","year":"2018","journal-title":"Exp Dermatol"},{"key":"R7-20250129","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1111\/j.1365-4362.1976.tb00173.x","article-title":"Crusted scabies alias Norwegian scabies","volume":"15","author":"Parish","year":"1976","journal-title":"Int J Dermatol"},{"key":"R8-20250129","first-page":"565","article-title":"Histocompatibility (HLA) antigens in Egyptians with two parasitic skin diseases (scabies and leishmaniasis)","volume":"20","author":"Morsy","year":"1990","journal-title":"J Egypt Soc Parasitol"},{"key":"R9-20250129","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.jinf.2004.08.033","article-title":"Crusted scabies:Clinical and immunological findings in seventy-eight patients and a review of the literature","volume":"50","author":"Roberts","year":"2005","journal-title":"J Infect"},{"key":"R10-20250129","first-page":"243","article-title":"Crusted scabies in Dakar apropos of 11 cases seen in a year","volume":"44","author":"Dia","year":"1999","journal-title":"Dakar Med"},{"key":"R12-20250129","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.1111\/jdv.14351","article-title":"European guideline for the management of scabies","volume":"31","author":"Salavastru","year":"2017","journal-title":"J Eur Acad Dermatol Venereol"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_569_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:38:18Z","timestamp":1787067498000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_569_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":10,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_569_24","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"2024-04-05","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-06-03","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}