{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T01:28:37Z","timestamp":1792718917187,"version":"4.5.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"9","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"\n Background:<\/jats:title>\n Infectious Keratitis (Ik) Is A Potential Vision-Threatening Ocular Infection Caused By A Variety Of Microorganisms.<\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n To Explore Risk Factors And Etiological Agents Associated With Ik.<\/jats:p>\n <\/jats:sec>\n \n Design:<\/jats:title>\n A Prospective Cross-Sectional Study In Which Corneal Scrapings From 120 Suspected Cases Were Evaluated At A Tertiary Health Care Institute From January To December 2019.<\/jats:p>\n <\/jats:sec>\n \n Methods:<\/jats:title>\n Scrapings Were Subjected To Direct Microscopy, Culture, And Identification By Both Conventional Methods And Maldi-Tof-Ms. The Patient's Demographic Data And Predisposing Factors, If Any Were Recorded.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n The Mean Age Of Patients Was 48.9 Years And Predisposing Factors Were Documented In 46% (55\/120) Of Cases. Overall, Infective Etiology Could Be Established In 51% (\n N<\/jats:italic>\n = 61\/120) Of Cases. Fungal Growth In 26% (\n N<\/jats:italic>\n = 31\/120) Of Cases And Bacterial Growth In 22% (\n N<\/jats:italic>\n = 27\/120) Of Cases Was Obtained. Growth Of More Than One Species Of Fungi Or Growth Of Bacteria Along With Fungus Were Observed In 2% (\n N<\/jats:italic>\n = 3\/120) Of Cases. Of All The Fungal Isolates Obtained (\n N<\/jats:italic>\n = 34), The Most Common Isolate Was\n Fusarium<\/jats:italic>\n (18\/34) Followed By\n Aspergillus<\/jats:italic>\n (8\/34),\n Curvularia<\/jats:italic>\n (4\/34),\n Pseudallescheria Boydii<\/jats:italic>\n (3\/34), And\n Geotrichum<\/jats:italic>\n (1\/34). Among The Gram-Positive Bacterial Isolates (\n N<\/jats:italic>\n = 16),\n Staphyloccus Species<\/jats:italic>\n (15\/16) Were Isolated In Maximum Number Followed By\n Streptococcus Pneumoniae<\/jats:italic>\n (1\/16). Among The Gram-Negative Isolates (\n N<\/jats:italic>\n = 13),\n Pseudomonas<\/jats:italic>\n Species (8\/13) Were Isolated In Maximum Number Of Cases, Followed By\n Acinetobacter<\/jats:italic>\n (3\/13),\n Klebsiella Pneumoniae<\/jats:italic>\n (1\/13), And\n Escherichia Coli<\/jats:italic>\n (1\/13).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n For Initiating Appropriate Empirical Therapy, The Knowledge Of The Epidemiological Pattern Of Infectious Keratitis Of A Particular Geographical Region Is Crucial.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_630_20","type":"journal-article","created":{"date-parts":[[2020,9,27]],"date-time":"2020-09-27T08:49:53Z","timestamp":1601196593000},"page":"4576-4581","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":16,"title":["Etiological spectrum of infectious keratitis in the era of MALDI-TOF-MS at a tertiary care hospital"],"prefix":"10.4103","volume":"9","author":[{"given":"Ranjana","family":"Rohilla","sequence":"first","affiliation":[{"name":"Senior Resident, Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suneeta","family":"Meena","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aroop","family":"Mohanty","sequence":"additional","affiliation":[{"name":"Assistant Professor, Department of Microbiology, All India Institute of Medical Sciences, Rishikesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neeti","family":"Gupta","sequence":"additional","affiliation":[{"name":"Associate Professor, Department of Ophthalmology, All India Institute of Medical Sciences, Rishikesh, 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