{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:35:01Z","timestamp":1786988101123,"version":"build-2736575974"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"8","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>Rheumatoid nodules (RNs) are the most common extraarticular manifestation in patients with rheumatoid arthritis, appearing in up to 30%. They are typically localized subcutaneously in pressure points or joints, such as the extensor surface of the elbow. But when they have atypical localizations, they provide a confusing differential diagnosis including the possibility of a malignancy. Herein, we report a 53-year-old female patient with known rheumatoid arthritis who presented with a painless mass in the right cubital fossa. The uncommon site and the presence of cortical disruption made us proceed to computed tomography-guided biopsy to exclude the presence of a malignancy. Biopsy established the RN diagnosis.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_641_20","type":"journal-article","created":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T05:57:47Z","timestamp":1598939867000},"page":"4434-4436","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A giant rheumatoid nodule of the cubital fossa: A mimicker of malignancy"],"prefix":"10.4103","volume":"9","author":[{"given":"Sofia-Chrysovalantou","family":"Zagalioti","sequence":"first","affiliation":[{"name":"General Practitioner, Papageorgiou Hospital, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza","family":"Stavride","sequence":"additional","affiliation":[{"name":"Department of Radiology, Papageorgiou Hospital, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonia","family":"Bintoudi","sequence":"additional","affiliation":[{"name":"Department of Radiology, Papageorgiou Hospital, Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2020,8]]},"reference":[{"key":"R1-20260817","first-page":"286","article-title":"Extra-articular manifestations in rheumatoid arthritis","volume":"5","author":"Cojocaru","year":"2010","journal-title":"Maedica (Buchar)"},{"key":"R2-20260817","doi-asserted-by":"crossref","first-page":"3041","DOI":"10.1007\/s10067-019-04668-1","article-title":"Clinicopathologic features of rheumatoid nodules: A retrospective analysis","volume":"38","author":"Seongsik","year":"2019","journal-title":"Clin Rheumatol"},{"key":"R3-20260817","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1136\/ard.8.4.258","article-title":"Muscle lesions in rheumatoid arthritis","volume":"8","author":"Horwitz","year":"1949","journal-title":"Ann Rheum Dis"},{"key":"R4-20260817","first-page":"127","article-title":"Diffuse rheumatoid nodules in skeletal muscle in rheumatoid arthritis","volume":"32","author":"Cs\u00e1sz\u00e1r","year":"1984","journal-title":"Acta Morphol Hung"},{"key":"R5-20260817","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/art.1780130107","article-title":"Bone erosion in relation to subcutaneous rheumatoid nodules","volume":"13","author":"Dorfman","year":"1979","journal-title":"Arthritis Rheum"},{"key":"R6-20260817","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1136\/ard.57.10.578","article-title":"\u201cRheumatoid nodules\u201d and lymphoma!","volume":"57","author":"Courtney","year":"1998","journal-title":"Ann Rheum Dis"},{"key":"R7-20260817","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1177\/0145561319849379","article-title":"Rheumatoid nodule of the vocal fold with spontaneous regression from immunosuppressant therapy","volume":"99","author":"Timashpolsky","year":"2020","journal-title":"Ear Nose Throat J"},{"key":"R8-20260817","first-page":"3","article-title":"The giant rheumatoid nodule: A case report","volume":"5","author":"Gupta","year":"2017","journal-title":"Gen Med"},{"key":"R9-20260817","doi-asserted-by":"crossref","first-page":"978e15","DOI":"10.1016\/j.crad.2019.08.025","article-title":"Thenar lumps: A review of differentials","volume":"74","author":"Ganguly","year":"2019","journal-title":"Clin Radiol"},{"key":"R10-20260817","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1016\/j.autrev.2019.05.007","article-title":"Challenges in the treatment of rheumatoid arthritis","volume":"18","author":"Conigliaro","year":"2019","journal-title":"Autoimmun Rev"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_641_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T17:01:02Z","timestamp":1786986062000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_641_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,8]]},"references-count":10,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2020]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_641_20","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,8]]},"assertion":[{"value":"2020-04-16","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-26","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}