{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:01:57Z","timestamp":1787169717803,"version":"build-2736575974"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"abstract":"<jats:p>\n                    Primary pyogenic ventriculitis is more commonly manifested in children. Its presentation in adults due to\n                    <jats:italic toggle=\"yes\">Streptococcus pneumonia<\/jats:italic>\n                    is rarely reported. It is mainly due to adequate vaccination cover and initiation of appropriate antibiotics. Ventriculitis is one of the complications of bacterial meningitis, requires long-term antibiotics and surgical intervention. Here, we are reporting a 67-year-old diabetic lady presented with a decrease in sensorium, seizure, and fever, diagnosed as bacterial ventriculitis. Her cerebro spinal fluid (CSF) picture suggestive of pyogenic meningitis, CSF, blood culture grew\n                    <jats:italic toggle=\"yes\">Streptoccous pneumoniae<\/jats:italic>\n                    ; MRI revealed \u2013ventriculitis. She was treated with Injection Ceftriaxazone for 6 week duration. Serial MRI showed clearing of ventricular debris and she improved. This highlights the atypical presentation of pyogenic meningitis without nuchal rigidity, status epilepticus, and clinical improvement without the need of surgical intervention.\n                  <\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_688_19","type":"journal-article","created":{"date-parts":[[2019,11,18]],"date-time":"2019-11-18T00:29:28Z","timestamp":1574036968000},"page":"3745-3747","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":16,"title":["Primary pyogenic ventriculitis caused by Streptococcal pneumoniae in adults"],"prefix":"10.4103","volume":"8","author":[{"given":"Chavada I.","family":"Jayendrakumar","sequence":"first","affiliation":[{"name":"Department of Medicine- Endocrinology, Pondicherry Institute of Medical Sciences, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh B.","family":"Ganesan","sequence":"additional","affiliation":[{"name":"Department of Medicine- Endocrinology, Pondicherry Institute of Medical Sciences, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddhant J.","family":"Thampi","sequence":"additional","affiliation":[{"name":"Department of Medicine- Endocrinology, Pondicherry Institute of Medical Sciences, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasanthi","family":"Natarajan","sequence":"additional","affiliation":[{"name":"Department of Medicine- Endocrinology, Pondicherry Institute of Medical Sciences, Puducherry, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2019,11]]},"reference":[{"key":"R2-20260528","doi-asserted-by":"crossref","first-page":"e005078","DOI":"10.1099\/jmmcr.0.005078","article-title":"Primary pyogenic ventriculitis caused byNeisseria meningitis: Case report and review of the literature","volume":"4","author":"Gronthoud","year":"2017","journal-title":"JMM Case 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and meningitis caused by Streptococcus acidominimus in humans: A case report","volume":"19","author":"Shah","year":"2018","journal-title":"Am J Case Rep"},{"key":"R10-20260528","doi-asserted-by":"crossref","DOI":"10.1093\/omcr\/omz044","article-title":"Life-threatening pyogenic ventriculitis, complicating endocarditis, presenting as sudden hearing loss","author":"Ito","year":"2019","journal-title":"Oxf Med Case Rep2019"},{"key":"R11-20260528","first-page":"1510","article-title":"CT and MR imaging features of pyogenic ventriculitis","volume":"22","author":"Fukui","year":"2001","journal-title":"Am J Neuroradiol"},{"key":"R12-20260528","first-page":"133","article-title":"The duration of antibiotic therapy in bacterial meningitis with pyogenic ventriculitis","volume":"59","author":"Tokimura","year":"2019","journal-title":"RinshoShinkeigaku"},{"key":"R13-20260528","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1097\/01.ccm.0000551341.38569.86","article-title":"Pyogenic ventriculitis: An unusual complication of streptococcal meningitis","volume":"47","author":"Farooq","year":"2019","journal-title":"Crit Care Med"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_688_19","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T19:12:28Z","timestamp":1787166748000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_688_19"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,11]]},"references-count":12,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2019]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_688_19","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,11]]},"assertion":[{"value":"2019-08-25","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication 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