{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:22:48Z","timestamp":1791616968466,"version":"4.3.4"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Dengue fever is a mosquito borne viral infection caused by a Flavivirus with four serotypes named DENV 1 to 4, is becoming a significant public health hazard. The spectrum of dengue presentation varis from asymptomatic to severe dengue. Neurological manifestation in dengue fever is an unusual presentation, however metabolic encephalopathy\/vascular strokes, resulting with organ dysfunction occurs in severe dengue infection. We report a case series of 12 dengue patients having encephalopathy from Odisha, Bhubaneswar from a total of 2065 diagnosed dengue positive patients during May 2019 to Jan 2024. Clinically dengue encephalopathy patients diagnosed from altered sensorium with metabolic and radiological parameters. In addition, complications of dengue fever had been compiled. We present these 12 cases having dengue encephalopathy with varied complication and managed with immediate clinical interventions to prevent negative outcomes and to improve the quality of life through early detection. Mortality was one out of 12 cases.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_698_24","type":"journal-article","created":{"date-parts":[[2025,1,13]],"date-time":"2025-01-13T09:05:03Z","timestamp":1736759103000},"page":"447-451","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Clinical profile of dengue encephalopathy: A series of twelve cases and a profile of other complications"],"prefix":"10.4103","volume":"14","author":[{"given":"Biswajit","family":"Bhuyan","sequence":"first","affiliation":[{"name":"Department of Hematology, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bandita","family":"Panda","sequence":"additional","affiliation":[{"name":"Department of Research and Development, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rabinarayan","family":"Rout","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lalatendu","family":"Mohanty","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bangam","family":"Rajendra Prasad Rao","sequence":"additional","affiliation":[{"name":"Department of General Medicine, Kalinga Institute of Medical Sciences (KIMS), Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,1,13]]},"reference":[{"key":"R2-20260109","doi-asserted-by":"crossref","first-page":"206","DOI":"10.4103\/0974-777X.81707","article-title":"A case of dengue encephalitis with intracerebral hemorrhage","volume":"3","author":"Khanna","year":"2011","journal-title":"J Glob Infect Dis"},{"key":"R3-20260109","doi-asserted-by":"crossref","first-page":"581","DOI":"10.4103\/0028-3886.68654","article-title":"Neurological complications of dengue infection","volume":"58","author":"Murthy","year":"2010","journal-title":"Neurol India"},{"key":"R4-20260109","doi-asserted-by":"crossref","first-page":"bcr2012008229","DOI":"10.1136\/bcr-2012-008229","article-title":"A rare case of dengue encephalitis","author":"Rao","year":"2013","journal-title":"BMJ Case Rep 2013"},{"key":"R5-20260109","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4103\/jgid.jgid_357_20","article-title":"Dengue encephalitis: A rare but dreaded complication of dengue fever","volume":"13","author":"Singh","year":"2021","journal-title":"J Glob Infect Dis"},{"key":"R6-20260109","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.jns.2011.04.010","article-title":"Dengue encephalitis: Suggestion for case definition","volume":"306","author":"Soares","year":"2011","journal-title":"J Neurol Sci"},{"key":"R7-20260109","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1055\/s-0031-1277983","article-title":"Encephalopathies caused by electrolyte disorders","volume":"31","author":"Samuels","year":"2011","journal-title":"Semin Neurol"},{"key":"R8-20260109","first-page":"948","article-title":"Guillain-Barre syndrome following dengue fever","volume":"41","author":"Sulekha","year":"2004","journal-title":"Indian Pediatr"},{"key":"R9-20260109","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s101560200030","article-title":"Acute disseminated encephalomyelitis following dengue fever","volume":"8","author":"Yamamoto","year":"2002","journal-title":"J Infect Chemother"},{"key":"R10-20260109","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.jns.2006.01.011","article-title":"Neurological manifestations of dengue virus infection","volume":"244","author":"Misra","year":"2006","journal-title":"J Neurol Sci"},{"key":"R11-20260109","doi-asserted-by":"crossref","first-page":"848","DOI":"10.4269\/ajtmh.2001.65.848","article-title":"Prospective case-control study of encephalopathy in children with dengue hemorrhagic fever","volume":"65","author":"Cam","year":"2001","journal-title":"Am J Trop Med Hyg"},{"key":"R12-20260109","doi-asserted-by":"crossref","first-page":"190","DOI":"10.4103\/0972-5229.84896","article-title":"Dengue encephalitis","volume":"15","author":"Borawake","year":"2011","journal-title":"Indian J Crit Care Med"},{"key":"R13-20260109","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1007\/s00234-020-02511-y","article-title":"Bilateral lesions of the basal ganglia and thalami (central grey matter)\u2014Pictorial review","volume":"62","author":"Van Cauter","year":"2020","journal-title":"Neuroradiology"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_698_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:46:50Z","timestamp":1787773610000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_698_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":12,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_698_24","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"2024-04-26","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-12","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}