{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:41:34Z","timestamp":1786650094473,"version":"build-2736575974"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Fever is a common symptom encountered in clinical practice. Hyperthermia, though infrequently encountered, can be genetical (malignant hyperthermia) or acquired when the body temperature rises beyond a certain set point that is controlled by the hypothalamus. We report a case of an elderly male who reported to us with hyperthermia, accelerated hypertension, and brain haemorrhage (as a sequelae of uncontrolled hypertension). A thorough clinical history pointed towards neuroleptic malignant syndrome (NMS). A remarkable response was observed with dantrolene and bromocriptine along with the discontinuation of the offending drug. With conservative management, the patient had complete recovery. This case highlights the importance of even sub-therapeutic drug dosage, particularly neuropsychiatric drugs, in the development of neurological catastrophe.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_724_22","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T07:25:32Z","timestamp":1671607532000},"page":"7430-7433","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Hyperthermia and neurological catastrophe: An interesting case report"],"prefix":"10.4103","volume":"11","author":[{"given":"Khyati","family":"Thapliyal","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, BLK-Max Super Speciality Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashutosh","family":"Garg","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, BLK-Max Super Speciality Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek P.","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, BLK-Max Super Speciality Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,12,16]]},"reference":[{"key":"R1-20260109","first-page":"439","article-title":"Neurolept malignant syndrome:Case report and discussion","volume":"169","author":"Geethan","year":"2013","journal-title":"CMAJ"},{"key":"R2-20260109","first-page":"769576","article-title":"Neurolept malignant syndrome:A case aimed at raising clinical awareness","volume":"2015","author":"Jad","year":"2015","journal-title":"Case Rep Med"},{"key":"R3-20260109","first-page":"168","article-title":"Neurolept malignant syndrome (a case report)","volume":"37","author":"Patkar","year":"1991","journal-title":"J Postgrad Med"},{"key":"R4-20260109","doi-asserted-by":"crossref","first-page":"2404","DOI":"10.1002\/ccr3.4049","article-title":"Neurolept malignant syndrome in a patient with moderate intellectual disability treated with olanzapine:A case report","volume":"9","author":"Francesco","year":"2021","journal-title":"Clin Case Rep"},{"key":"R5-20260109","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1176\/ajp.2007.164.6.870","article-title":"Neurolept malignant syndrome","volume":"164","author":"Strawn","year":"2007","journal-title":"Am J Psychiatry"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_724_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:02:11Z","timestamp":1786647731000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_724_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":5,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_724_22","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11]]},"assertion":[{"value":"2022-03-29","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-07-25","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}