{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:34:51Z","timestamp":1787070891795,"version":"build-2736575974"},"reference-count":13,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Snake bite is a well-known occupational hazard amongst farmers, plantation workers, and other outdoor workers and results in much morbidity and mortality throughout the world. The complications related to kidneys are observed in most patients with snake bites admitted to a hospital. The current study aimed to study the renal involvement in patients with snake bites with reference to clinical features and the time of onset of acute renal failure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A prospective clinical study of 68 patients of snake bite was done to know the clinical profile and outcome in Gandhi Hospital Secunderabad and cases were particularly looked for development of acute kidney injury. Later each case was studied and investigated with respect to onset, clinical features, course in the hospital, need for renal replacement therapy including dialysis, and mortality due to AKI. Patients were followed up till discharge or death. They were treated as per protocol.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The incidence of AKI was 29.1%. Common signs and symptoms were fang mark (100%), swelling (91.2%), tenderness (91.2%), bleeding manifestations (79.4%) oliguria (26.47%), anuria (5.8%), and haematuria (8.8%). Hypotension was present in 73%, which may be the cause of AKI. All the AKI patients showed coagulation abnormalities in the form of prolonged BT, CT, PT, and aPTT. Thrombocytopenia was seen in 29.4%. All the AKI patients were given ASV for 2 to 3 days. The mean ASV vials used in the present study is 15 \u00b1 5. Hemodialysis was done in 29.4% of patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The cause of AKI in snakebite was multifactorial in origin. Bleeding and hypotension were among the important causes. Thrombocytopenia was significantly related to clinical bleeding. The type of snakebite is an important factor in the development of AKI and Russell\u2019s viper bite is more commonly associated with it. AKI is usually associated with oliguria and generally occurs within 48 hours.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_784_24","type":"journal-article","created":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T04:02:01Z","timestamp":1731729721000},"page":"5301-5305","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":6,"title":["A study of clinical profile and outcome of patients with snake bite-induced acute kidney injury"],"prefix":"10.4103","volume":"13","author":[{"given":"Avunoori","family":"Pushpalatha","sequence":"first","affiliation":[{"name":"Department of General Medicine, Government Medical College, Bhadradri Kothagudem, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afreen Begum H.","family":"Itagi","sequence":"additional","affiliation":[{"name":"Department of Physiology, All India Institute of Medical Sciences (AIIMS), Mangalagiri, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Immadi S.","family":"Vamshidhar","sequence":"additional","affiliation":[{"name":"Department of Physiology, All India Institute of Medical Sciences (AIIMS), Mangalagiri, Andhra Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S. S. Sabitha","family":"Rani","sequence":"additional","affiliation":[{"name":"Department of Pathology, Government Medical College, Bhadradri Kothagudem, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Medala","family":"Kalpana","sequence":"additional","affiliation":[{"name":"Department of Physiology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ganji","family":"Vidya","sequence":"additional","affiliation":[{"name":"Department of Physiology, All India Institute of Medical Sciences (AIIMS), Bibinagar, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"R2-20250129","first-page":"515","article-title":"Snake-bites:Appraisal of the global situation","volume":"76","author":"Chippaux","year":"1998","journal-title":"Bull World Health Organ"},{"key":"R3-20250129","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/S0272-6386(84)80023-2","article-title":"Acute renal failure following poisonous snakebite","volume":"4","author":"Chugh","year":"1984","journal-title":"Am J Kidney Dis"},{"key":"R4-20250129","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4065\/76.1.67","article-title":"Acute renal failure:A practical update","volume":"76","author":"Albright","year":"2001","journal-title":"Mayo Clin Proc"},{"key":"R5-20250129","doi-asserted-by":"crossref","first-page":"594","DOI":"10.4103\/1947-2714.120795","article-title":"Clinical predictors of acute kidney injury following snake bite envenomation","volume":"5","author":"Dharod","year":"2013","journal-title":"N Am J Med Sci"},{"key":"R6-20250129","first-page":"123","article-title":"Acute renal failure following poisonous snake bite","volume":"40","author":"Mittal","year":"1994","journal-title":"J Postgrad Med"},{"key":"R7-20250129","doi-asserted-by":"crossref","first-page":"197","DOI":"10.4103\/0975-2870.110314","article-title":"Vasculotoxic snake bite presenting with sepsis, acute renal failure, disseminated intravascular coagulation, and acute respiratory distress syndrome","volume":"6","author":"Bhausaheb","year":"2013","journal-title":"Med J Dr. D. 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Patil Univ"},{"key":"R8-20250129","first-page":"311","article-title":"Clinical profile of Snake Bite in a Tertiary care Hospital in South India","volume":"6","author":"Raghavendra","year":"2017","journal-title":"Int J Sci Res"},{"key":"R9-20250129","doi-asserted-by":"crossref","first-page":"48","DOI":"10.9790\/0853-1605054850","article-title":"Epidemiology, clinical profile of snake bite cases treated in Theni medical college hospital, in South India","volume":"16","author":"Vallidevi","year":"2017","journal-title":"IOSR J Dent Med Sci"},{"key":"R10-20250129","first-page":"853","article-title":"A study on the acute kidney injury in snake bite victims in a tertiary care center","volume":"7","author":"Harshvardhan","year":"2013","journal-title":"J Clin Diagn Res"},{"key":"R11-20250129","doi-asserted-by":"crossref","first-page":"18","DOI":"10.36106\/ijar\/8915693","article-title":"Epidemiology and Clinical features of snakebite induced acute kidney injury patients in last decade and its long term outcome. A single-entry experience","volume":"12","author":"Banerjee","year":"2022","journal-title":"Indian J Appl Res"},{"key":"R12-20250129","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1136\/emj.2007.051136","article-title":"Snakebite envenoming in Kerala, South India:Clinical profile and factors involved in adverse outcomes","volume":"25","author":"Suchithra","year":"2008","journal-title":"Emerg Med J"},{"key":"R13-20250129","doi-asserted-by":"crossref","first-page":"19117","DOI":"10.18535\/jmscr\/v5i3.129","article-title":"Early prediction of acute kidney injury by clinical and biochemical parameters in snakebite patients","volume":"5","author":"Panchalwar","year":"2017","journal-title":"J Med Sci Clin Res"},{"key":"R14-20250129","first-page":"7","article-title":"Acute Renal failure in patients with Venomous snakebite","volume":"9","author":"Srilatha","year":"1997","journal-title":"Indian J Trop Med"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_784_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:38:25Z","timestamp":1787067505000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_784_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11]]},"references-count":13,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_784_24","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11]]},"assertion":[{"value":"2024-05-09","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}