{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:42:42Z","timestamp":1786650162709,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Helicobacter pylori<\/jats:italic>\n                      (\n                      <jats:italic toggle=\"yes\">H. pylori<\/jats:italic>\n                      ) is one of the most common human infections worldwide particularly in the developing countries. We aimed to study an association of\n                      <jats:italic toggle=\"yes\">H. Pylori<\/jats:italic>\n                      infection with endoscopic and histological findings in the Nepalese population.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>We conducted a study between Oct 2014 and Jan 2015 after meeting inclusion and exclusion criteria. Institutional Review Board approval was obtained from National Academy of Medical Sciences. Endoscopic findings and histopathological diagnosis were documented and data were analysed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 113 patients who had complete endoscopy were enrolled. The prevalence of\n                      <jats:italic toggle=\"yes\">H. pylori<\/jats:italic>\n                      infections recorded was 27 (23.9%) patients. There were 17 (62%) male and 10 (37%) female infected with\n                      <jats:italic toggle=\"yes\">H. pylori<\/jats:italic>\n                      (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.33). All biopsied specimens were sent to pathology lab for examination. The most common endoscopic findings was erythematous antral gastritis (40.7%) followed by erosive gastritis 34 (30.1%), pangastritis 10 (8.8%), duodenal ulcer 13 (11.5%), gastric ulcer 9 (8%), erosive fundal gastritis 2 (1.8%), reflux esophagitis 10 (37%) (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.04). Histology revealed that 23 (85.2%) patients had chronic active gastritis (CAG); (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>\n                      Our study revealed that\n                      <jats:italic toggle=\"yes\">H. pylori<\/jats:italic>\n                      infection is strongly associated with chronic active gastritis (CAG) and Reflux esophagitis in Nepalese adults.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_82_19","type":"journal-article","created":{"date-parts":[[2019,3,28]],"date-time":"2019-03-28T01:06:00Z","timestamp":1553735160000},"page":"1227-1231","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["An association of Helicobacter pylori infection with endoscopic and histological findings in the Nepalese population"],"prefix":"10.4103","volume":"8","author":[{"given":"Amrendra Kumar","family":"Mandal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paritosh","family":"Kafle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pradeep","family":"Puri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baikuntha","family":"Chaulagai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasdeep S.","family":"Sidhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukesh 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