{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T20:36:54Z","timestamp":1790800614595,"version":"4.1.0"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Background:<\/jats:title>\n Tuberculosis (TB) is still a global health issue. While the lungs are the most commonly affected, infections can also affect other organs. Because of the rise in immunocompromised hosts, the number of opportunistic infections has skyrocketed. In instances of aspergilloma and chronic pulmonary aspergillosis (CPA), pulmonary tuberculosis (PTB) is the most usually linked condition.<\/jats:p>\n <\/jats:sec>\n \n Material and Methods:<\/jats:title>\n The current cross-sectional study was conducted on 42 study participants from January 2018 to June 2019.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n Aspergilloma was observed in two participants (4.8%) of the study population.\n Candida<\/jats:italic>\n growth was observed in five participants (11.9%) of the study population on sputum fungal culture.\n Aspergillus<\/jats:italic>\n growth and\n Candida<\/jats:italic>\n growth was observed in three (7.1%) and two (4.8%) participants of the study population, respectively, on bronchoalveolar lavage (BAL) fungal culture.\n Aspergillus<\/jats:italic>\n IgG antibody was positive in four particpants (9.5%) of study population. Out of the 42 participants, four were diagnosed with CPA.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Since CPA and PTB patients present similar symptoms, it is virtually impossible to distinguish between the two unless serological test is performed. There has been a significant burden of patients with CPA, especially in post tuberculosis fibro-cavitation. CPA patients requires long-term anti-fungal therapy; hence an improved case detection should be undertaken.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jfmpc.jfmpc_846_22","type":"journal-article","created":{"date-parts":[[2023,2,16]],"date-time":"2023-02-16T08:20:08Z","timestamp":1676535608000},"page":"106-110","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":8,"title":["Prevalence of chronic pulmonary aspergillosis in fibrocavitary pulmonary tuberculosis patients"],"prefix":"10.4103","volume":"12","author":[{"given":"Rakesh","family":"Rajpurohit","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, BYL and Nair Hospital, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj","family":"Wagh","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, JNMC, Wardha, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mamta","family":"Heda","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Dr. PDMMC, Amravati, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gaurav","family":"Dubey","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Dr. PDMMC, Amravati, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pankaj S.","family":"Gujar","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Dr. PDMMC, Amravati, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,2,15]]},"reference":[{"key":"R2-20240828","first-page":"621","article-title":"Pulmonary aspergilloma:Analysis of cavitating invasive pulmonary aspergillosis in immunocompromised patients","volume":"53","author":"Jewkes","year":"1983","journal-title":"Ann ThoracSurg"},{"key":"R3-20240828","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/j.ijid.2009.07.011","article-title":"Clinical characteristics and treatment outcomes of chronic necrotizing pulmonary aspergillosis:A review of 43 cases","volume":"14","author":"Nam","year":"2010","journal-title":"Int J Infect Dis"},{"key":"R4-20240828","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s10096-003-0970-y","article-title":"Significance of aspergillusfumigatus isolation from respiratory specimens of nongranulocytopenic patients","volume":"22","author":"Uffredi","year":"2003","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"R5-20240828","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1183\/09031936.00054810","article-title":"Underlying conditions in chronic pulmonary aspergillosis including simple aspergilloma","volume":"37","author":"Smith","year":"2011","journal-title":"Eur Respir J"},{"issue":"(Sup 1)","key":"R6-20240828","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1080\/13693780400025179","article-title":"The invasive and saprophytic syndromes due to Aspergillus spp","volume":"43","author":"Hope","year":"2005","journal-title":"Med Mycol"},{"key":"R7-20240828","first-page":"201","article-title":"Prevalence of aspergillosis in chronic lung diseases","volume":"19","author":"Shahid","year":"2001","journal-title":"Indian J Med Microbiol"},{"key":"R8-20240828","doi-asserted-by":"crossref","first-page":"74","DOI":"10.4103\/ijaai.ijaai_18_18","article-title":"Clinical, radiological, and microbiological profile of pulmonary aspergillosis in treated cases of pulmonary tuberculosis","volume":"32","author":"Jain","year":"2018","journal-title":"Indian J Allergy Asthma Immunol"},{"key":"R9-20240828","doi-asserted-by":"crossref","first-page":"e000155","DOI":"10.1136\/bmjresp-2016-000155","article-title":"Clinical manifestations and outcomes of pulmonary aspergillosis:Experience from Pakistan","volume":"3","author":"Iqbal","year":"2016","journal-title":"BMJ Open Respir Res"},{"key":"R10-20240828","doi-asserted-by":"crossref","first-page":"850","DOI":"10.5588\/ijtld.13.0838","article-title":"Prevalence of Aspergillussensitisation in pulmonary tuberculosis-related fibrocavitary disease","volume":"18","author":"Dhooria","year":"2014","journal-title":"Int J Tuberc Lung Dis"},{"key":"R11-20240828","first-page":"201","article-title":"Prevalence of aspergillosis in chronic lung diseases","volume":"19","author":"Shahid","year":"2001","journal-title":"Indian J Med Microbiol."},{"key":"R12-20240828","first-page":"23","article-title":"Serodiagnosis of pulmonary aspergillosis","volume":"15","author":"Vijayachari","year":"1997","journal-title":"Indian J Med Microbiol"}],"container-title":["Journal of Family Medicine and Primary Care"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_846_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T16:06:51Z","timestamp":1787760411000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jfmpc.jfmpc_846_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":11,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/jfmpc.jfmpc_846_22","relation":{},"ISSN":["2249-4863","2278-7135"],"issn-type":[{"value":"2249-4863","type":"print"},{"value":"2278-7135","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"2022-04-12","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-09","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}