{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:27:15Z","timestamp":1787840835878,"version":"build-2784847793"},"reference-count":17,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"11","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,11]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by damage to organs and cells, initially mediated by tissue-binding autoantibodies and immune complexes. Lymphomas have been frequently reported, but the association of SLE with acute leukemia is rare and likely coincidental. We report a case of a 40-year-old female admitted for an etiological diagnosis of fever and dyspnea with peripheral edema. She had a history of SLE diagnosed 2 years prior and had been on immunosuppressive therapy since then. Hematological investigations showed leukocytosis, anemia, and thrombocytopenia. Further diagnostic testing could not be done as she passed away 3 days after acute leukemia was diagnosed. This case highlights the challenges of diagnosing hematological malignancies in immunosuppressed SLE patients where symptoms may be obscured.<\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_874_24","type":"journal-article","created":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T04:03:01Z","timestamp":1731729781000},"page":"5402-5406","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Challenges in diagnosing concurrent acute leukemia in an immunosuppressed patient with systemic lupus erythematosus: A case report"],"prefix":"10.4103","volume":"13","author":[{"given":"Shaily","family":"Agrawal","sequence":"first","affiliation":[{"name":"Second-Year MBBS Student, Shri MP Shah Medical College, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit K.","family":"Jangir","sequence":"additional","affiliation":[{"name":"Second-Year MBBS Student, Shri MP Shah Medical College, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M","family":"Yogesh","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Shri MP Shah Medical College, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohankumar","family":"Gandhi","sequence":"additional","affiliation":[{"name":"Department of Community Medicine, Shri MP Shah Medical College, Jamnagar, Gujarat, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,11,18]]},"reference":[{"key":"R1-20250129","doi-asserted-by":"crossref","first-page":"750","DOI":"10.1002\/ajh.21241","article-title":"Combined pure red cell aplasia and autoimmune hemolytic anemia in systemic lupus erythematosus with anti-erythropoietin autoantibodies","volume":"83","author":"Hara","year":"2008","journal-title":"American Journal of 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