{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:25:43Z","timestamp":1787772343754,"version":"build-2784847793"},"reference-count":11,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>\n                    Malignant phyllodes, along with ductal carcinoma, is known as metaplastic cancer of the breast. This tumor is additionally known as breast carcinosarcoma. Malignant phyllodes in conjunction with ductal carcinoma is a rare finding in routine clinical practice. We describe the case report of a 47-year-old female patient who arrived with a large right breast mass. A core biopsy was performed, and histopathological examination indicated that the tumor was a malignant phyllodes tumor. A positron emission tomography (PET) scan revealed hyper-metabolic and hypo-metabolic tumors with perilesional stranding and satellite nodularity. There were a few metastatic right axillary nodes visible. There was no indication of distant metastases. Due to the presence of both components, a modified radical mastectomy surgery with axillary dissection was undertaken for this patient. Histopathological analysis of paraffin sections revealed ductal carcinoma\n                    <jats:italic toggle=\"yes\">in situ<\/jats:italic>\n                    (DCIS) comedo-epithelial component and spindle-shaped cells with hyper-chromatic oval nuclei and scanty cytoplasm.\n                  <\/jats:p>","DOI":"10.4103\/jfmpc.jfmpc_983_23","type":"journal-article","created":{"date-parts":[[2024,5,23]],"date-time":"2024-05-23T06:02:08Z","timestamp":1716444128000},"page":"2149-2151","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Carcinosarcoma of breast \u2013 A chimera among breast neoplasms"],"prefix":"10.4103","volume":"13","author":[{"given":"Vandana","family":"Tomey","sequence":"first","affiliation":[{"name":"Department of Surgery, Datta Meghe Medical College and Shalinitai Meghe Hospital and Research Centre, Wanadongri, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raj Kumar","family":"Ashwini Kumar","sequence":"additional","affiliation":[{"name":"Department of Surgery, Datta Meghe Medical College and Shalinitai Meghe Hospital and Research Centre, Wanadongri, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pravin","family":"Nikhade","sequence":"additional","affiliation":[{"name":"Department of Surgery, Datta Meghe Medical College and Shalinitai Meghe Hospital and Research Centre, Wanadongri, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anil","family":"Akulwar","sequence":"additional","affiliation":[{"name":"Department of Surgery, Datta Meghe Medical College and Shalinitai Meghe Hospital and Research Centre, Wanadongri, Nagpur, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,5,24]]},"reference":[{"key":"R1-20240828","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4103\/njs.NJS_27_18","article-title":"Rare breast malignancy subtypes:A cytological, histological, and immunohistochemical correlation","volume":"25","author":"Kaur","year":"2019","journal-title":"Niger J Surg"},{"key":"R2-20240828","first-page":"193","article-title":"Biologic distinctions and therapeutic implications of sarcomatoid metaplasia of epithelial carcinoma of the breast","volume":"180","author":"Gutman","year":"1995","journal-title":"J Am Coll Surg"},{"key":"R3-20240828","first-page":"e28551","article-title":"Metaplastic breast cancer:Characteristics and survival outcomes","volume":"14","author":"Thapa","year":"2022","journal-title":"Cureus"},{"key":"R4-20240828","first-page":"128","article-title":"Sarcomatoid neoplasms of the breast:Proposed definitions for 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Cancer"},{"key":"R8-20240828","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1093\/annonc\/mdl006","article-title":"Biphasic metaplastic sarcomatoid carcinoma of the breast","volume":"17","author":"Hennessy","year":"2006","journal-title":"Ann Oncol"},{"key":"R9-20240828","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1136\/jcp.2004.025163","article-title":"Metaplastic breast carcinomas are negative for Her-2 but frequently express EGFR (Her-1):Potential relevance to adjuvant treatment with EGFR tyrosine kinase inhibitors?","volume":"58","author":"Leibl","year":"2005","journal-title":"J Clin Pathol"},{"key":"R10-20240828","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1038\/sj.bjc.6601504","article-title":"Additive antitumour effect of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (Iressa, ZD1839) and the antioestrogen fulvestrant (Faslodex, ICI 182,780) in breast cancer cells","volume":"90","author":"Okubo","year":"2004","journal-title":"Br J Cancer"},{"key":"R11-20240828","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1186\/s13058-020-01353-z","article-title":"A comprehensive overview of metaplastic breast cancer:Clinical features and molecular aberrations","volume":"22","author":"Reddy","year":"2020","journal-title":"Breast Cancer Res"}],"container-title":["Journal of Family Medicine and Primary 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History"}},{"value":"2023-12-08","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}