{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:27:56Z","timestamp":1786739276060,"version":"build-2736575974"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Varicella-zoster virus (VZV) is a DNA virus belonging to the Herpesviridae family. Primary infection causes chickenpox followed by latency in the sensory ganglia, which can sometimes reactivate leading to herpes zoster. Chicken pox is generally a mild disease of childhood with a secondary attack rate of &gt;85%, but disseminated VZV infection with visceral involvement and fatal outcome may occur in immunocompromised individuals. Indian Academy of Pediatrics recommends two doses of live-attenuated varicella vaccine in healthy unexposed children at 15\u201318 months and then at 4\u20136 years of age. The effectiveness of a single dose of vaccine is around 85% and with a two-dose schedule is as high as 92%. Despite the vaccine-induced protection, community-acquired VZV infections still remain a problem in immunocompromised population. We hereby report a case of a previously immunized pediatric liver-transplant recipient who acquired VZV infection. This case report clearly highlights the importance of strict environmental infection control practices, early suspicion, diagnosis, and management in such cases.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jgid.jgid_233_20","type":"journal-article","created":{"date-parts":[[2021,8,18]],"date-time":"2021-08-18T06:34:27Z","timestamp":1629268467000},"page":"142-144","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Varicella Infection in an Immunized Pediatric Living Donor Liver-Transplant Recipient"],"prefix":"10.4103","volume":"13","author":[{"given":"Vibha","family":"Mehta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krithiga","family":"Ramachandran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reshu","family":"Agarwal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seema","family":"Alam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viniyendra","family":"Pamecha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ekta","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-7-20240828","first-page":"714","article-title":"Age related seroprevalence of antibodies to varicella in India","volume":"37","author":"Lokeshwar","year":"2000","journal-title":"Indian Pediatr"},{"key":"R3-7-20240828","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/j.ijid.2003.09.006","article-title":"A review of the varicella vaccine in immunocompromised individuals","volume":"8","author":"Sartori","year":"2004","journal-title":"Int J Infect Dis"},{"key":"R4-7-20240828","doi-asserted-by":"crossref","first-page":"785","DOI":"10.1007\/s13312-014-0504-y","article-title":"Indian Academy of Pediatrics (IAP) recommended immunization schedule for children aged 0 through 18 years \u2013 India, 2014 and updates on immunization","volume":"51","author":"Vashishtha","year":"2014","journal-title":"Indian Pediatr"},{"key":"R5-7-20240828","first-page":"e44","article-title":"2013 IDSA clinical practice guideline for vaccination of the immunocompromised host","volume":"58","author":"Rubin","year":"2014","journal-title":"ClinInfect Dis"},{"key":"R6-7-20240828","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1111\/j.1600-6143.2012.04273.x","article-title":"Varicella-zoster immunization in pediatric liver transplant recipients: Safe and immunogenic","volume":"12","author":"Posfay-Barbe","year":"2012","journal-title":"Am J Transplant"},{"key":"R7-7-20240828","doi-asserted-by":"crossref","first-page":"e13622","DOI":"10.1111\/ctr.13622","article-title":"On behalf of the AST Infectious Diseases Community of Practice. Varicella zoster virus in solid organ transplantation: Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice","volume":"33","author":"Pergam","year":"2019","journal-title":"Clin Transplant"},{"key":"R8-7-20240828","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1016\/S0377-1237(09)80028-2","article-title":"Chickenpox appearing in previously vaccinated individuals","volume":"65","author":"Suryam","year":"2009","journal-title":"Med J Armed Forces India"},{"key":"R9-7-20240828","doi-asserted-by":"crossref","first-page":"S214","DOI":"10.1016\/j.mjafi.2014.03.011","article-title":"Reinfection of Varicella zoster in a vaccinated adult","volume":"71","author":"Dubey","year":"2015","journal-title":"Med J Armed Forces India"},{"key":"R10-7-20240828","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.phoj.2019.07.001","article-title":"Varicella vaccination in children with acute lymphoblastic leukemia: Experience from a pediatric cancer centre in India","volume":"4","author":"Guru","year":"2019","journal-title":"Pediatric Hematol Oncol J"}],"container-title":["Journal of Global Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jgid.jgid_233_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:27:31Z","timestamp":1786735651000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jgid.jgid_233_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7]]},"references-count":9,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jgid.jgid_233_20","relation":{},"ISSN":["0974-777X"],"issn-type":[{"value":"0974-777X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7]]}}}