{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:24:09Z","timestamp":1787844249972,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Oral cavity involvement in tuberculosis (TB), particularly palatine, is extremely rare and mostly described in case reports. Management of these cases usually responds to classic antitubercular therapy. Some serious complications such as paradoxical reactions (PRs) may however occur, making it more challenging for physicians to treat and to manage. We present a case of a 30-year-old female patient with a history of juvenile idiopathic arthritis and systemic lupus erythematosus who presented a bifocal form of TB involving the palate and the cervical lymph nodes. Follow-up after 2 months of proper antitubercular treatment revealed a PR of the lymph nodes contrasting with a favorable outcome of the oral lesions. It seems useful to raise all clinicians' awareness to suspect TB when they deal with chronic drug-resistant oral erosions and to keep in mind the diagnosis of PR when there is a worsening of one lesion and a favorable outcome of another.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jgid.jgid_266_20","type":"journal-article","created":{"date-parts":[[2021,5,31]],"date-time":"2021-05-31T10:58:13Z","timestamp":1622458693000},"page":"94-96","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Palate Tuberculosis with Paradoxical Lymphadenitis"],"prefix":"10.4103","volume":"13","author":[{"given":"Ines","family":"Kechaou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rym","family":"Abida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohamed Salah","family":"Hamdi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lamia Ben","family":"Hassine","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-7-20240828","first-page":"521","article-title":"Tuberculosis of the oral cavity","volume":"56","author":"Neme\u015f","year":"2015","journal-title":"Rom J Morphol Embryol"},{"key":"R2-7-20240828","first-page":"32","article-title":"Primary tuberculosis of palate","volume":"10","author":"Chen","year":"2015","journal-title":"Malays Fam Physician"},{"key":"R3-7-20240828","doi-asserted-by":"crossref","first-page":"803","DOI":"10.1007\/s10096-002-0821-2","article-title":"Clinical spectrum of paradoxical deterioration during antituberculosis therapy in non-HIV-infected patients","volume":"21","author":"Cheng","year":"2002","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"R4-7-20240828","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ijid.2014.12.030","article-title":"Paradoxical reaction and immune reconstitution inflammatory syndrome in tuberculosis","volume":"32","author":"Bell","year":"2015","journal-title":"Int J Infect Dis"},{"key":"R5-7-20240828","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1007\/s15010-017-1112-2","article-title":"Vacuum-assisted closure therapy of paradoxical reaction in tuberculous lymphadenopathy caused by Mycobacterium africanum","volume":"46","author":"Geerdes-Fenge","year":"2018","journal-title":"Infection"},{"key":"R6-7-20240828","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.ijid.2016.10.025","article-title":"Paradoxical reaction associated with cervical lymph node tuberculosis: Predictive factors and therapeutic management","volume":"54","author":"Chahed","year":"2017","journal-title":"Int J Infect Dis"},{"key":"R7-7-20240828","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.pneumo.2016.09.002","article-title":"Paradoxical reaction following antituberculosis therapy in immunocompetent patient","volume":"72","author":"Bacha","year":"2016","journal-title":"Rev Pneumol Clin"},{"key":"R8-7-20240828","doi-asserted-by":"crossref","first-page":"e706","DOI":"10.1097\/MJT.0b013e3181fa0dc0","article-title":"A unique paradoxical reaction to tuberculosis therapy: Case report and brief review of the literature","volume":"20","author":"Singh","year":"2013","journal-title":"Am J Ther"},{"key":"R9-7-20240828","doi-asserted-by":"crossref","first-page":"318","DOI":"10.1016\/j.pneumo.2010.11.006","article-title":"Paradoxical lymphadenopathy during treatment of cavitary tuberculosis in an immunocompetent patient","volume":"67","author":"Rakotoson","year":"2011","journal-title":"Rev Pneumol Clin"}],"container-title":["Journal of Global Infectious Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jgid.jgid_266_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T15:15:40Z","timestamp":1787843740000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jgid.jgid_266_20"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jgid.jgid_266_20","relation":{},"ISSN":["0974-777X"],"issn-type":[{"value":"0974-777X","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4]]}}}