{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:27:50Z","timestamp":1787772470973,"version":"build-2784847793"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"\n Objective:<\/jats:title>\n To study the possibility of creating mucosal valve mechanism at ureteric orifice without obstructing the urine outflow but preventing the urine backflow into the ureters.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n Ethical waiver was obtained from the institutional ethical committee. Prospective experimental study was conducted on the post-mortem specimen of intact bladder with urethra and bilateral ureters retrieved from the already slaughtered lamb available in the meat market. Feeding tube inserted via urethral opening into the bladder lumen and bladder inflated with saline demonstrated no reflux of urine via transverse cut opening of ureters. Bladder lumen opened, ureteric orifices incised backwards to eliminate the obliquity. After closing the bladder opening, saline inflation test demonstrated bilateral reflux of saline via cut openings of bilateral ureters. Bladder was re-opened. The upper limb of horizontal U started 10 mm lateral and 8 mm above the refluxing ureteric orifice. Distal most curvature of horizontal U was kept 5 mm medial to ureteric orifice continuing along the lower limb of horizontal U terminating 10 mm lateral and 8 mm below the refluxing ureteric orifice, mucosal flaps from superior and inferior incision mobilized and edges joined to cover the ureteric orifice creating a flap valve mechanism. Influx of saline via cut end of ureters demonstrated no obstruction. Bladder was closed. Saline inflation test and contrast study demonstrated abolition of reflux on flap side and persistence of reflux on another side.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Five such experiments were conducted. On the side where the valve was created, Vesicoureteral reflux was abolished in four but in one minimal reflux still persisted.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Creating a mucosal flap valve around the ureteric orifice can prevent reflux in 80% of cases without obstruction and without the necessity of ureteric mobilization or creating submucosal tunnel.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_143_21","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T10:14:36Z","timestamp":1716545676000},"page":"462-465","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Study the Possibility of Creating Mucosal Valve Mechanism at Ureteric Orifice without Obstructing the Urine Outflow but Preventing the Urine Backflow into the Ureters"],"prefix":"10.4103","volume":"27","author":[{"given":"Nirpex","family":"Tyagi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiv","family":"Kureel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Archika","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gurmeet","family":"Singh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Rai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nitin","family":"Pant","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-16-20240905","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/S0022-5347(17)68223-5","article-title":"Vesico-ureteral reflux in the paraplegic: Cause and correction","volume":"68","author":"Hutch","year":"1952","journal-title":"J Urol"},{"key":"R2-16-20240905","doi-asserted-by":"crossref","first-page":"932","DOI":"10.1016\/S0022-5347(17)66369-9","article-title":"An operative technique for the correction of vesicoureteral reflux","volume":"79","author":"Politano","year":"1958","journal-title":"The Journal of urology"},{"key":"R3-16-20240905","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/S0022-5347(17)65934-2","article-title":"Ureterovesical anastomosis: The description and evaluation of a technique","volume":"82","author":"Paquin","year":"1959","journal-title":"J Urol"},{"key":"R4-16-20240905","doi-asserted-by":"crossref","first-page":"554","DOI":"10.1016\/S0022-5347(17)65219-4","article-title":"Recurrent urosepsis in children","volume":"86","author":"Lich","year":"1961","journal-title":"J Urol"},{"key":"R5-16-20240905","first-page":"431","article-title":"The surgical treatment of congenital vesico-ureteral reflux","volume":"63","author":"Gregoir","year":"1964","journal-title":"Acta Chir Belg"},{"key":"R6-16-20240905","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/S0022-5347(17)63089-1","article-title":"Distal tunnel ureteral reimplantation","volume":"97","author":"Glenn","year":"1967","journal-title":"J Urol"},{"key":"R7-16-20240905","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/S0022-5347(17)50447-4","article-title":"A new technique for surgical correction of vesicoureteral reflux","volume":"131","author":"Gil-Vernet","year":"1984","journal-title":"J Urol"},{"key":"R8-16-20240905","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1111\/j.1464-410X.1986.tb05894.x","article-title":"Endoscopic correction of primary vesicoureteric reflux","volume":"58","author":"O\u2019Donnell","year":"1986","journal-title":"Br J Urol"},{"key":"R11-16-20240905","doi-asserted-by":"crossref","first-page":"17","DOI":"10.4103\/0971-9261.125949","article-title":"Creation of effective antireflux mechanism without creation of submucosal tunnel in surgical correction of vesicoureteric reflux: Myth or reality?-An experimental study","volume":"19","author":"Gupta","year":"2014","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"R12-16-20240905","doi-asserted-by":"crossref","first-page":"70","DOI":"10.4103\/jiaps.JIAPS_81_17","article-title":"Technique of antireflux procedure without creating submucosal tunnel for surgical correction of vesicoureteric reflux during bladder closure in exstrophy","volume":"23","author":"Sunil","year":"2018","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"R13-16-20240905","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1097\/01.ju.0000135673.28496.70","article-title":"Extracellular matrix degradation and reduced nerve supply in refluxing ureteral endings","volume":"172","author":"Oswald","year":"2004","journal-title":"J Urol"},{"key":"R14-16-20240905","first-page":"1","article-title":"Ureterocutaneoustomy. Anew antireflux technique","volume":"6","author":"Cohen","year":"1975","journal-title":"Current Urology"}],"container-title":["Journal of Indian Association of Pediatric Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_143_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:47:55Z","timestamp":1787770075000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_143_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,7]]},"references-count":12,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jiaps.jiaps_143_21","relation":{},"ISSN":["0971-9261"],"issn-type":[{"value":"0971-9261","type":"print"}],"subject":[],"published":{"date-parts":[[2022,7]]}}}