{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T20:32:10Z","timestamp":1786739530886,"version":"build-2736575974"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>The aim of this study was to review the clinical profile, management, and outcome of solid tumors in the head-and-neck region in children at our institute.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We retrospectively reviewed children with head-and-neck solid tumors who were treated jointly under the departments of Pediatric Surgery and Otorhinolaryngology at our institute between 2016 and 2019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In the study period, 10 children (6 males, 4 females) with a median age of 9.5 years (range 5 days\u201316 years) were treated by our unit. The patients had four tumors arising from the parotid, 2 from nose\/naso-pharynx, 1 each from the tongue, submandibular gland, para-pharyngeal space, and infratemporal fossa. A majority (90%) of the patients underwent complete surgical excision of the tumor, preserving the loco-regional neurovascular structures to minimize postoperative morbidity. Malignant lesions were seen in 4 patients (2 rhabdomyosarcoma, 1 primitive neuro-ectodermal tumor, 1 mucoepidermoid carcinoma) and 6 patients had benign pathology (3 pleomorphic adenoma, 2 mature teratoma, 1 schwanomma). Additional therapy with chemotherapy and local radiotherapy was required in 3 out of 4 patients with malignant pathology. The median follow-up duration is 15 months. At last follow-up, all patients are alive and 9 out of 10 patients (90%) are disease-free.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Our experience highlights rare and difficult tumors in the head-and-neck region in children. These tumors are not commonly managed by the pediatric surgeon in routine practice. The paper outlines the multi-modality management of these tumors, which is essential for an optimal outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_145_20","type":"journal-article","created":{"date-parts":[[2021,9,16]],"date-time":"2021-09-16T04:48:08Z","timestamp":1631767688000},"page":"299-306","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Head-and-Neck Solid Tumors in Children"],"prefix":"10.4103","volume":"26","author":[{"given":"Ravi Sankar","family":"Manogaran","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankur","family":"Mandelia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Govind","family":"Bhuskute","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arulalan","family":"Mathialagan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20240905","doi-asserted-by":"crossref","first-page":"2536","DOI":"10.12659\/MSM.891052","article-title":"Pediatric head and neck tumors: An intra-demographic analysis using the SEER* database","volume":"20","author":"Cesmebasi","year":"2014","journal-title":"Med Sci Monit"},{"key":"R2-4-20240905","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1542\/peds.58.2.218","article-title":"The incidence of birthmarks in the neonate","volume":"58","author":"Jacobs","year":"1976","journal-title":"Pediatrics"},{"key":"R3-4-20240905","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1001\/archotol.126.12.1435","article-title":"Masses of the salivary gland region in children","volume":"126","author":"Bentz","year":"2000","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R4-4-20240905","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1002\/hed.2890080309","article-title":"Salivary neoplasms: Overview of a 35-year experience with 2,807 patients","volume":"8","author":"Spiro","year":"1986","journal-title":"Head Neck Surg"},{"key":"R5-4-20240905","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1016\/j.ijporl.2007.07.019","article-title":"Pleomorphic adenoma of the parotid gland in children","volume":"71","author":"Rodriguez","year":"2007","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"R6-4-20240905","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1177\/000348948409300304","article-title":"Benign pleomorphic adenomas in children","volume":"93","author":"Malone","year":"1984","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"R7-4-20240905","doi-asserted-by":"crossref","first-page":"566","DOI":"10.3390\/jcm8050566","article-title":"Characteristics of 5015 Salivary Gland Neoplasms Registered in the Hiroshima Tumor Tissue Registry over a Period of 39 Years","volume":"8","author":"Sentani","year":"2019","journal-title":"J Clin Med"},{"key":"R8-4-20240905","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1001\/archotol.132.4.375","article-title":"Mucoepidermoid carcinoma of the parotid gland in children: A 10-year experience","volume":"132","author":"Rahbar","year":"2006","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R9-4-20240905","doi-asserted-by":"crossref","first-page":"849","DOI":"10.1001\/archotol.130.7.849","article-title":"Mucoepidermoid carcinoma of the parotid gland: the Mayo clinic experience","volume":"130","author":"Boahene","year":"2004","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R10-4-20240905","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1002\/hed.21477","article-title":"Mucoepidermoid carcinoma of the parotid gland: Factors affecting outcome","volume":"33","author":"Ghosh-Laskar","year":"2011","journal-title":"Head Neck"},{"key":"R11-4-20240905","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1177\/0194599811417063","article-title":"Head and neck rhabdomyosarcoma: A critical analysis of population-based incidence and survival data","volume":"145","author":"Turner","year":"2011","journal-title":"Otolaryngol Head Neck Surg"},{"key":"R12-4-20240905","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1200\/JCO.1995.13.3.610","article-title":"The third intergroup rhabdomyosarcoma study","volume":"13","author":"Crist","year":"1995","journal-title":"J Clin Oncol"},{"key":"R13-4-20240905","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1001\/archotol.126.4.468","article-title":"Pediatric rhabdomyosarcoma of the head and neck: is there a place for surgical management?","volume":"126","author":"Daya","year":"2000","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R14-4-20240905","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/hed.10260","article-title":"Malignant peripheral primitive neuroectodermal tumor-peripheral neuroepithelioma of the head and neck: a clinicopathologic study of five cases and review of the literature","volume":"25","author":"Nikitakis","year":"2003","journal-title":"Head Neck"},{"key":"R15-4-20240905","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1001\/archotol.1990.01870040097022","article-title":"Extracranial primitive neuroectodermal tumor of the head and neck","volume":"116","author":"Chowdhury","year":"1990","journal-title":"Arch Otolaryngol Head Neck Surg"},{"key":"R16-4-20240905","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1097\/01.pas.0000146006.46468.ef","article-title":"Congenital teratoma: A clinicopathologic study of 22 fetal and neonatal tumors","volume":"29","author":"Heerema-McKenney","year":"2005","journal-title":"Am J Surg Pathol"},{"key":"R17-4-20240905","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1016\/j.ijporl.2017.02.011","article-title":"Teratoma of the neonatal head and neck: A 41-year experience","volume":"97","author":"Brodsky","year":"2017","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"R18-4-20240905","doi-asserted-by":"crossref","first-page":"E12","DOI":"10.1053\/jpsu.2003.50150","article-title":"Ultrasonographic guidance for location of the trachea during the EXIT procedure for cervical teratoma","volume":"38","author":"Myers","year":"2003","journal-title":"J Pediatr Surg"},{"key":"R19-4-20240905","first-page":"137","article-title":"Lingual schwannoma: Case report and review of the literature","volume":"33","author":"Lira","year":"2013","journal-title":"Acta Otorhinolaryngol Ital"}],"container-title":["Journal of Indian Association of Pediatric Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.JIAPS_145_20","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:29:45Z","timestamp":1786735785000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.JIAPS_145_20"}},"subtitle":["A Retrospective Review from a Tertiary Care Institute in North India"],"short-title":[],"issued":{"date-parts":[[2021,9]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2021]]}},"URL":"https:\/\/doi.org\/10.4103\/jiaps.jiaps_145_20","relation":{},"ISSN":["0971-9261"],"issn-type":[{"value":"0971-9261","type":"print"}],"subject":[],"published":{"date-parts":[[2021,9]]}}}