{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T20:03:34Z","timestamp":1787169814910,"version":"build-2736575974"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2021,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Benign renal tumors are extremely rare and were studied here. This series also includes a renal teratoma in a horseshoe kidney, probably only the second in the pediatric literature.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Retrospective review of children with benign renal tumors operated between 2006 and 2018 at one center.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Twelve patients (M:F ratio 10:2), age range 3 weeks (31-week gestation) to 13 years presented with large palpable renal swelling (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 12) and hematuria (\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 3). Computed tomography (CT) scan showed features typical of the tumor. Final histopathology (age group [mean]) showed: multilocular cystic nephroma (MLCN) -\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 5 (41.7%), (11\u201316 months [13.6]); congenital mesoblastic nephroma (CMN) -\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 4 (33.3%) (classic 1, cellular 3) (0.75\u20135 months [2.125]); mature cystic teratoma -\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 1 (8.3%): (48 months, in a horseshoe kidney), and angiomyolipoma (AML) -\n                      <jats:italic toggle=\"yes\">n<\/jats:italic>\n                      = 2 (16.7%) (144 months [sporadic] and 156 months [tuberous sclerosis]) One patient with cystic teratoma with no calcification on CT scan received pre-operative chemotherapy as fine-needle aspiration cytology (FNAC) reported malignant small blue cell tumor. Nephroureterectomy with Gerota's fascia could be done easily in all without intraoperative complications. Delay in presentation in MLCN and CMN led to increased symptoms and CT scan changes. All patients did well in 1.5\u201312 years (median 3 years) follow-up including cellular mesoblastic nephroma.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Benign renal tumors often occur in specific age groups but may overlap that of Wilms tumor. Proper interpretation of clinical presentation, CT scan, and FNAC findings help in avoiding preoperative chemotherapy. Upfront nephroureterectomy is curative. Histopathological findings decide further treatment. Children with AML and tuberous sclerosis need lifelong follow-up.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_214_20","type":"journal-article","created":{"date-parts":[[2021,11,12]],"date-time":"2021-11-12T03:59:23Z","timestamp":1636689563000},"page":"380-392","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Benign Renal Tumors in Pediatric Age Group"],"prefix":"10.4103","volume":"26","author":[{"given":"Prema","family":"Menon","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katragadda Lakshmi Narasimha","family":"Rao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saalim","family":"Nazki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saswati","family":"Behera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kirti","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ram","family":"Samujh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shailesh","family":"Solanki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshay","family":"Saxena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Deepak","family":"Bansal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amita","family":"Trehan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-4-20240905","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1002\/mpo.2950210305","article-title":"Epidemiology of Wilms tumor","volume":"21","author":"Breslow","year":"1993","journal-title":"Med Pediatr Oncol"},{"key":"R2-4-20240905","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1016\/j.jpedsurg.2008.02.077","article-title":"Imaging accuracy and incidence of Wilms' and non-Wilms' renal tumors in children","volume":"43","author":"Miniati","year":"2008","journal-title":"J Pediatr Surg"},{"key":"R3-4-20240905","doi-asserted-by":"crossref","first-page":"1130","DOI":"10.1002\/pbc.21389","article-title":"Characteristics and survival of 750 children diagnosed with a renal tumor in the first seven months of life: A collaborative study by the SIOP\/GPOH\/SFOP, NWTSG, and UKCCSG Wilms tumor study groups","volume":"50","author":"van den Heuvel-Eibrink","year":"2008","journal-title":"Pediatr Blood Cancer"},{"key":"R4-4-20240905","doi-asserted-by":"crossref","first-page":"e26437","DOI":"10.1002\/pbc.26437","article-title":"Congenital mesoblastic nephroma 50 years after its recognition: A narrative review","volume":"64","author":"Gooskens","year":"2017","journal-title":"Pediatr Blood Cancer"},{"key":"R5-4-20240905","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1002\/pbc.22871","article-title":"Mesoblastic nephroma: A report of the United Kingdom children's cancer and leukaemia group (CCLG)","volume":"56","author":"England","year":"2011","journal-title":"Pediatr Blood Cancer"},{"key":"R6-4-20240905","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1136\/jcp.44.4.317","article-title":"Congenital mesoblastic nephroma: Possible prognostic and management value of assessing DNA content","volume":"44","author":"Barrantes","year":"1991","journal-title":"J Clin Pathol"},{"key":"R7-4-20240905","doi-asserted-by":"crossref","first-page":"826","DOI":"10.1016\/S0022-3468(82)80451-X","article-title":"Therapy and outcome in 51 children with mesoblastic nephroma: A report of the national Wilms' tumor study","volume":"17","author":"Howell","year":"1982","journal-title":"J Pediatr Surg"},{"key":"R8-4-20240905","doi-asserted-by":"crossref","first-page":"2275","DOI":"10.1002\/cncr.21836","article-title":"Mesoblastic nephroma--a report from the Gesellschaft fur P\u00e4diatrische Onkologie und H\u00e4matologie (GPOH)","volume":"106","author":"Furtwaengler","year":"2006","journal-title":"Cancer"},{"key":"R9-4-20240905","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.1097\/PAS.0b013e318299f2d1","article-title":"The international society of urological pathology (ISUP) Vancouver classification of renal Neoplasia","volume":"37","author":"Srigley","year":"2013","journal-title":"Am J Surg Pathol"},{"key":"R10-4-20240905","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1016\/j.juro.2006.09.011","article-title":"SIOP\/GPOH Study Group. 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