{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T12:46:45Z","timestamp":1791377205390,"version":"4.3.2"},"reference-count":8,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2025,1,2]],"date-time":"2025-01-02T00:00:00Z","timestamp":1735776000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>In closed gastroschisis, the initial herniation of the intestines through the abdominal wall defect subsequently leads to spontaneous closure of the defect during fetal development, even before the migration of the intestines back to the abdominal domain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This study investigates the clinical presentation, diagnostic challenges, and management strategies of closed gastroschisis through a retrospective review of six cases presented at our clinic between 2009 and 2024. Data were prospectively collected and analyzed to gain insights into the varied presentations and outcomes of this rare condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In this cohort of six patients with closed gastroschisis, none had undergone antenatal ultrasonographic examination, and all presented to the emergency department immediately after birth with a mass protruding from the abdominal wall. Each patient underwent evaluation and laparotomy for definitive management. Five of the six children showed favorable outcomes at the 48-month follow-up, while one patient succumbed to postoperative sepsis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Abdominal wall defects, including closed gastroschisis, are congenital anomalies requiring prompt diagnosis and treatment. This rare variant presents unique challenges in management due to its atypical features. The findings from this study contribute to a better understanding of closed gastroschisis and its management, highlighting the importance of early diagnosis and intervention in improving patient outcomes in pediatric surgical practice. Antenatal diagnosis and prompt surgical intervention as early as possible after birth are the mainstays of treatment.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_224_24","type":"journal-article","created":{"date-parts":[[2025,1,3]],"date-time":"2025-01-03T01:01:28Z","timestamp":1735866088000},"page":"183-189","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["Challenges in Managing Closed Gastroschisis: Addressing a Rare and Complex Variant of Abdominal Wall Defect"],"prefix":"10.4103","volume":"30","author":[{"given":"Ajay","family":"Verma","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devendra K.","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jitendra K.","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, M.L.N. Medical College, Allahabad, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachit","family":"Anand","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,1,2]]},"reference":[{"key":"R1-20250304","first-page":"72","article-title":"A proposed classification for the spectrum of vanishing gastroschisis","volume":"23","author":"Kumar","year":"2013","journal-title":"Eur J Pediatr Surg"},{"key":"R2-20250304","doi-asserted-by":"crossref","first-page":"bcr2017223846","DOI":"10.1136\/bcr-2017-223846","article-title":"Closed gastroschisis with left defect: A rare variant","volume":"2018","author":"Singh","year":"2018","journal-title":"BMJ Case Rep"},{"key":"R3-20250304","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1016\/j.jpedsurg.2008.02.023","article-title":"Closed gastroschisis:Total parenteral nutrition-free survival with aggressive attempts at bowel preservation and intestinal adaptation","volume":"43","author":"Vogler","year":"2008","journal-title":"J Pediatr Surg"},{"key":"R4-20250304","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1055\/s-0030-1261884","article-title":"Midgut atresia and spontaneously closed gastroschisis: Support for a mechanical explanation","volume":"21","author":"Dahl","year":"2011","journal-title":"Eur J Pediatr Surg"},{"key":"R5-20250304","doi-asserted-by":"crossref","first-page":"65","DOI":"10.21699\/jns.v5i4.416","article-title":"Closed gastroschisis with vanished small bowel and jejunal atresia","volume":"5","author":"Sisodiya","year":"2016","journal-title":"J Neonatal Surg"},{"key":"R6-20250304","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.jpedsurg.2008.10.084","article-title":"Closing gastroschisis: Diagnosis, management, and outcomes","volume":"44","author":"Houben","year":"2009","journal-title":"J Pediatr Surg"},{"key":"R7-20250304","doi-asserted-by":"crossref","first-page":"719","DOI":"10.7863\/jum.1994.13.9.719","article-title":"Gastroschisis followed by absorption of the small bowel and closure of the abdominal wall defect","volume":"13","author":"Pinette","year":"1994","journal-title":"J Ultrasound Med"},{"key":"R8-20250304","doi-asserted-by":"crossref","first-page":"1288","DOI":"10.1016\/S0022-3468(96)90253-5","article-title":"Gastroschisis complicated by midgut atresia and closure of the defect in utero","volume":"31","author":"Bhatia","year":"1996","journal-title":"J Pediatr Surg"}],"container-title":["Journal of Indian Association of Pediatric Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_224_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T19:27:11Z","timestamp":1786735631000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_224_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,2]]},"references-count":8,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jiaps.jiaps_224_24","relation":{},"ISSN":["0971-9261","1998-3891"],"issn-type":[{"value":"0971-9261","type":"print"},{"value":"1998-3891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,2]]},"assertion":[{"value":"2024-09-29","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-16","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}