{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:26:35Z","timestamp":1787765195144,"version":"build-2784847793"},"reference-count":9,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"\n A\n BSTRACT<\/jats:sc>\n <\/jats:title>\n \n Aim:<\/jats:title>\n The aim is to study intrahepatic biliary architecture in patients following Kasai\u2019s portoenterostomy for extrahepatic biliary atresia using magnetic resonance cholangiopancreatography (MRCP).<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n It is a prospective observational study in a cohort of patients who have survived with a complete jaundice-free period for at least 1 year. MRCP was done to look for various intrahepatic architectural changes during their last visit. Findings were correlated with liver functions and growth and development.<\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n Twenty-one patients were included in the study. The male-to-female sex ratio was 1.6:1, the median age at surgery was 75 days (18\u2013140 days), and the median age at magnetic resonance imaging (MRI) was 4 years (18 months\u201318 years). More than 2 years of follow-up was in seven patients. Left lobe hypertrophy was observed in six patients, right lobe hypertrophy was in three patients, intrahepatic biliary tract dilatation was in five patients, and altered signal intensity between intrahepatic ducts was seen in five patients. In addition, hypointense foci in the spleen were seen in one patient. Twelve children had normal weight for their age, ten children had the normal height for their age, and gamma-glutamyl transferase was elevated in all children. Only four children had a history of fever and jaundice.<\/jats:p>\n <\/jats:sec>\n \n Conclusions:<\/jats:title>\n The patients who survive after successful surgical intervention have near-normal liver gross architecture as on MRI\/MRCP. Occasional findings of dilatation and lobar atrophy\/hypertrophy are possible, especially in those with a history of cholangitis. The survivors also have acceptable growth parameters and normal liver functions.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_24_23","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T14:00:52Z","timestamp":1705500052000},"page":"23-27","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Study of Intrahepatic Biliary Architecture in Patients Operated for Extrahepatic Biliary Atresia using Magnetic Resonance Cholangiopancreatography"],"prefix":"10.4103","volume":"29","author":[{"given":"Ajay","family":"Verma","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjan Kumar","family":"Dhua","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devasenathipathy","family":"Kandasamy","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis and Interventional Radiology, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Veereshwar","family":"Bhatnagar","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, ESIC Medical College and Hospital, Faridabad, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,1,12]]},"reference":[{"key":"R1-20240905","first-page":"430","article-title":"Long-term survival following Kasai portoenterostomy:Is chronic liver disease inevitable?","volume":"37","author":"Hadzi\u0107","year":"2003","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"R2-20240905","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1016\/j.jpedsurg.2008.11.054","article-title":"Histologic features of the portal plate in extrahepatic biliary atresia and their impact on prognosis \u2013A Danish study","volume":"44","author":"Mirza","year":"2009","journal-title":"J Pediatr Surg"},{"key":"R3-20240905","doi-asserted-by":"crossref","first-page":"1364","DOI":"10.1016\/S0022-3468(99)90012-X","article-title":"Incidence of intrahepatic biliary cysts in biliary atresia after hepatic portoenterostomy and associated histopathologic findings in the liver and porta hepatis at diagnosis","volume":"34","author":"Takahashi","year":"1999","journal-title":"J Pediatr Surg"},{"key":"R4-20240905","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/0022-3468(94)90728-5","article-title":"Cystic dilatation of the intrahepatic biliary system in biliary atresia after hepatic portoenterostomy","volume":"29","author":"Tsuchida","year":"1994","journal-title":"J Pediatr Surg"},{"key":"R5-20240905","doi-asserted-by":"crossref","first-page":"1797","DOI":"10.1016\/j.jpedsurg.2004.08.021","article-title":"Cholangitis as a late complication in long-term survivors after surgery for biliary atresia","volume":"39","author":"Nio","year":"2004","journal-title":"J Pediatr Surg"},{"key":"R6-20240905","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1111\/j.1478-3231.2011.02668.x","article-title":"Biliary atresia and survival into adulthood without transplantation:A collaborative multicentre clinic review","volume":"32","author":"Kumagi","year":"2012","journal-title":"Liver Int"},{"key":"R7-20240905","doi-asserted-by":"crossref","first-page":"2595","DOI":"10.1007\/s00261-021-02958-4","article-title":"Imaging rediction with ultrasound and MRI of long-term medical outcome in native liver survivor patients with biliary atresia after Kasai portoenterostomy:A pilot study","volume":"46","author":"Caruso","year":"2021","journal-title":"Abdom Radiol (NY)"},{"key":"R8-20240905","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1620\/tjem.181.193","article-title":"MRI findings in the liver in biliary atresia patients after the Kasai operation","volume":"181","author":"Takahashi","year":"1997","journal-title":"Tohoku J Exp Med"},{"key":"R9-20240905","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1111\/j.1442-200X.2008.02657.x","article-title":"Time-course changes in the liver of biliary atresia patients on magnetic resonance imaging","volume":"51","author":"Takahashi","year":"2009","journal-title":"Pediatr Int"}],"container-title":["Journal of Indian Association of Pediatric Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_24_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:03:45Z","timestamp":1787763825000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_24_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":9,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jiaps.jiaps_24_23","relation":{},"ISSN":["0971-9261","1998-3891"],"issn-type":[{"value":"0971-9261","type":"print"},{"value":"1998-3891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"assertion":[{"value":"2023-01-30","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-08-22","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}