{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T02:05:47Z","timestamp":1793325947734,"version":"4.5.0"},"reference-count":20,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,7]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Posterior urethral valves (PUV) are the most common obstructive anomaly of the lower urinary tract in children. End-stage renal disease (ESRD) in 17% of the children is due to PUV. The present study helps know the spectrum of the disease, management options, and the outcome in these children.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>The present study is a descriptive type of study by review of medical records of all the children presented to the hospital from 2015 to 2019. Profile of PUV includes any abnormality in antenatal ultrasonography (USG), age at presentation, presenting complaints, general condition at the time of presentation, biochemical investigations like serum creatinine and electrolytes at admission, clinical progression during hospital stay and the type of intervention. Outcome variables studied were improvement in the stream and overall well-being of the child, renal function, recurrent urinary tract infections (UTIs). Follow-up period varied from 1 to 6 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 73 patients were included in the study. The mean age of presentation was 3.4 years. The most common presenting complaints were poor urinary stream and dribbling of urine. Antenatal USG showed abnormality in 23 patients. Renal function was abnormal in 28 patients. Out of 73 patients, 51 underwent endoscopic ablation of valves, 19 underwent vesicostomy, and three patients underwent supravesical diversion. During the follow-up recurrent UTI was observed in 11 patients, 15 patients progressed to chronic kidney disease, and 15% of patients were hypertensive. Mortality in the present study was 4%.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>PUV includes a spectrum of diseases from mild form to lethal conditions. Early intervention by relieving obstruction may prevent or delay the ESRD; hence, timely intervention is necessary in these children.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_27_24","type":"journal-article","created":{"date-parts":[[2024,7,6]],"date-time":"2024-07-06T15:00:14Z","timestamp":1720278014000},"page":"364-369","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Profile, Management, and Outcome of Posterior Urethral Valves in Children \u2013 Experience from a Tertiary Care Hospital"],"prefix":"10.4103","volume":"29","author":[{"given":"Gali","family":"Divya","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay Kumar","family":"Kundal","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, All India Institute of Medical Sciences, Vijaypur, Jammu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajasekhar","family":"Addagatla","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Prathima Institute of Medical Sciences, Karimanagar, Telangana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritesh","family":"Kumar","sequence":"additional","affiliation":[{"name":"Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar, Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep Kumar","family":"Jaglan","sequence":"additional","affiliation":[{"name":"Rainbow Hospital, Model Town, Panipat, Haryana, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinaki Ranjan","family":"Debnath","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences, Dr. Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atul Kumar","family":"Meena","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences, Dr. Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shalu","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Atal Bihari Vajpayee Institute of Medical Sciences, Dr. Ram Manohar Lohia Hospital, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,7,6]]},"reference":[{"key":"R1-20240905","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1100\/tsw.2009.127","article-title":"Posterior urethral valves","volume":"9","author":"Hodges","year":"2009","journal-title":"ScientificWorldJournal"},{"key":"R2-20240905","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s12519-011-0289-1","article-title":"Posterior urethral valve","volume":"7","author":"Nasir","year":"2011","journal-title":"World J Pediatr"},{"key":"R3-20240905","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1016\/S0090-4295(02)01621-7","article-title":"Current trends in the management of posterior urethral valves in the pediatric population","volume":"60","author":"Yohannes","year":"2002","journal-title":"Urology"},{"key":"R5-20240905","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nrneph.2011.14","article-title":"Classification and staging of acute kidney injury:Beyond the RIFLE and AKIN criteria","volume":"7","author":"Ricci","year":"2011","journal-title":"Nat Rev Nephrol"},{"key":"R6-20240905","doi-asserted-by":"crossref","first-page":"825","DOI":"10.1007\/s00383-008-2163-3","article-title":"Clinical and radiological characteristics of Nigerian boys with posterior urethral valves","volume":"24","author":"Ikuerowo","year":"2008","journal-title":"Pediatr Surg Int"},{"key":"R7-20240905","doi-asserted-by":"crossref","first-page":"4","DOI":"10.4103\/jiaps.JIAPS_148_18","article-title":"Consensus on the management of posterior urethral valves from antenatal period to puberty","volume":"24","author":"Sharma","year":"2019","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"R9-20240905","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1464-410X.1988.tb04267.x","article-title":"Long-term outcome of boys with posterior urethral valves","volume":"62","author":"Parkhouse","year":"1988","journal-title":"Br J Urol"},{"key":"R10-20240905","doi-asserted-by":"crossref","first-page":"133","DOI":"10.4103\/0971-9261.136459","article-title":"Posterior urethral valve:Prognostic factors and renal outcome","volume":"19","author":"Bhadoo","year":"2014","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"R11-20240905","doi-asserted-by":"crossref","first-page":"18","DOI":"10.4103\/0189-6725.150937","article-title":"Presentation, management, and outcome of posterior urethral valves in a Nigerian tertiary hospital","volume":"12","author":"Orumuah","year":"2015","journal-title":"Afr J Paediatr Surg"},{"key":"R12-20240905","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/j.jpedsurg.2012.11.016","article-title":"Posterior urethral valves:Creatinine velocity, a new early predictor of renal insufficiency","volume":"48","author":"Coleman","year":"2013","journal-title":"J Pediatr Surg"},{"key":"R13-20240905","doi-asserted-by":"crossref","first-page":"3.e1","DOI":"10.1016\/j.jpurol.2015.04.007","article-title":"Combined creatinine velocity and nadir creatinine:A reliable predictor of renal outcome in neonatally diagnosed posterior urethral valves","volume":"11","author":"Coleman","year":"2015","journal-title":"J Pediatr Urol"},{"key":"R14-20240905","first-page":"531","article-title":"Posterior urethral valves;A single center experience","volume":"23","author":"Mirshemirani","year":"2013","journal-title":"Iran J Pediatr"},{"key":"R15-20240905","first-page":"148","article-title":"Clinical spectrum of posterior urethral valve obstruction in children","volume":"8","author":"Choudhury","year":"2003","journal-title":"J Indian Assoc Paed Surg"},{"key":"R16-20240905","doi-asserted-by":"crossref","first-page":"2222","DOI":"10.1016\/j.jpedsurg.2010.07.003","article-title":"Surgical complications of posterior urethral valve ablation:20 years experience","volume":"45","author":"Sarhan","year":"2010","journal-title":"J Pediatr Surg"},{"key":"R17-20240905","doi-asserted-by":"crossref","first-page":"37","DOI":"10.4103\/0970-1591.41011","article-title":"Advantages of fulguration of posterior urethral valves by Nd:YAG laser","volume":"17","author":"Gupta","year":"2000","journal-title":"Indian J Urol"},{"key":"R18-20240905","doi-asserted-by":"crossref","first-page":"80","DOI":"10.4103\/0971-9261.71744","article-title":"Posterior urethral valves:Morphological normalization of posterior urethra after fulguration is a significant factor in prognosis","volume":"15","author":"Menon","year":"2010","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"R19-20240905","doi-asserted-by":"crossref","first-page":"1252048","DOI":"10.3389\/fped.2023.1252048","article-title":"Editorial:Posterior urethral valves:Advances in diagnosis, management, and long-term follow up","volume":"11","author":"Garriboli","year":"2023","journal-title":"Front Pediatr"},{"key":"R20-20240905","doi-asserted-by":"crossref","first-page":"435","DOI":"10.4103\/0970-1591.36719","article-title":"A review of urodynamic evaluation in children and its role in the management of boys with posterior urethral valves","volume":"23","author":"Desai","year":"2007","journal-title":"Indian J Urol"},{"key":"R21-20240905","first-page":"1","article-title":"KDIGO 2012 clinical practice guideline for the evaluation and management of chronic kidney disease","volume":"3","year":"2013","journal-title":"Kidney Int Suppl"},{"key":"R22-20240905","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/s43159-020-00035-x","article-title":"The posterior urethral valves revisited:Embryological correlation, clinical classification, and risk stratification of the spectrum","volume":"16","author":"Sarma","year":"2020","journal-title":"Ann Pediatr Surg"}],"container-title":["Journal of Indian Association of Pediatric Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_27_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T13:54:40Z","timestamp":1787838880000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_27_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":20,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jiaps.jiaps_27_24","relation":{},"ISSN":["0971-9261","1998-3891"],"issn-type":[{"value":"0971-9261","type":"print"},{"value":"1998-3891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"2024-02-02","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-03-21","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}