{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:30:44Z","timestamp":1786728644433,"version":"build-2736575974"},"reference-count":5,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T00:00:00Z","timestamp":1769212800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,3]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Germ cell tumors (GCT) are most commonly observed in the gonads. Extragonadal GCTs (EGCT) are uncommon and are considered metastatic or primary tumors. Histologically and immunophenotypically, EGCTs resemble gonadal GCT. EGCTs in the gastrointestinal tract are extremely rare and are seen more frequently as metastases than primary tumors. Here, we discuss a case of primary mixed GCT of the stomach in a 4-year-old boy to highlight the fact that GCT should be considered in the differential diagnosis of any poorly differentiated epithelioid neoplasm in the pediatric population. The site should not hinder one from thinking of it. Histomorphological appearances, supporting immunohistochemistry, and tumor markers can help in establishing the correct diagnosis and ensuring the appropriate management of patients.<\/jats:p>","DOI":"10.4103\/jiaps.jiaps_343_25","type":"journal-article","created":{"date-parts":[[2026,1,25]],"date-time":"2026-01-25T01:00:06Z","timestamp":1769302806000},"page":"307-309","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Extragonadal Primary Mixed Germ Cell Tumor of the Stomach"],"prefix":"10.4103","volume":"31","author":[{"given":"Basharat","family":"Mubeen","sequence":"first","affiliation":[{"name":"Departments of Pathology, Gastroenterology, Pediatric Surgery and Medical Oncology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roopa Rachel","family":"Paulose","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Gastroenterology, Pediatric Surgery and Medical Oncology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anoop","family":"Koshy","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Gastroenterology, Pediatric Surgery and Medical Oncology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohan K","family":"Abraham","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Gastroenterology, Pediatric Surgery and Medical Oncology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anju","family":"Farsana","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Gastroenterology, Pediatric Surgery and Medical Oncology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keechilat","family":"Pavithran","sequence":"additional","affiliation":[{"name":"Departments of Pathology, Gastroenterology, Pediatric Surgery and Medical Oncology, Amrita Institute of Medical Sciences and Research Centre, Kochi, Kerala, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,1,24]]},"reference":[{"key":"R1-20260311","doi-asserted-by":"crossref","first-page":"1148505","DOI":"10.1155\/crpe\/1148505","article-title":"Primary yolk sac tumor of the stomach in a 2-year-old boy: Case report on a rare site for extragonadal malignant germ cell tumor","author":"Reddy","year":"2025","journal-title":"Case Rep Pediatr, 2025"},{"key":"R2-20260311","doi-asserted-by":"crossref","first-page":"2863","DOI":"10.1007\/s00345-022-04009-z","article-title":"How to classify, diagnose, treat and follow-up extragonadal germ cell tumors?A systematic review of available evidence","volume":"40","author":"Winter","year":"2022","journal-title":"World J Urol"},{"key":"R3-20260311","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1007\/s003830000390","article-title":"Gastric teratoma in children","volume":"16","author":"Gupta","year":"2000","journal-title":"Pediatr Surg Int"},{"key":"R4-20260311","doi-asserted-by":"crossref","first-page":"1004501","DOI":"10.3389\/fped.2022.1004501","article-title":"Preservation of sexual and reproductive function in the treatment of extragonadal yolk sac tumors in the female genital tract","volume":"10","author":"Ma","year":"2022","journal-title":"Front Pediatr"},{"key":"R5-20260311","doi-asserted-by":"crossref","first-page":"3563","DOI":"10.1200\/JCO.2004.01.006","article-title":"Treatment of children and adolescents with stage II testicular and stages I and II ovarian malignant germ cell tumors: A pediatric intergroup study \u2013Pediatric oncology group 9048 and children's cancer group 8891","volume":"22","author":"Rogers","year":"2004","journal-title":"J Clin Oncol"}],"container-title":["Journal of Indian Association of Pediatric Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_343_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:29:46Z","timestamp":1786724986000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_343_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,24]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026]]}},"URL":"https:\/\/doi.org\/10.4103\/jiaps.jiaps_343_25","relation":{},"ISSN":["0971-9261","1998-3891"],"issn-type":[{"value":"0971-9261","type":"print"},{"value":"1998-3891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,24]]},"assertion":[{"value":"2025-10-02","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-10","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}