{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T19:57:55Z","timestamp":1792180675737,"version":"4.4.0"},"reference-count":24,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,3]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>The aim of this study is to determine the surgical outcome of ileostomy closure at low body weight (&lt;1500 g) and to find any differences in complications and growth of infants whose ileostomy was reversed early (4\u20136 weeks) versus late (8\u201310 weeks).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A prospective comparative study was conducted on patients who underwent ileostomy reversal created for necrotizing enterocolitis from January 2017 to December 2019. The patients were divided into two groups: group 1 (early ileostomy closure) between 4 and 6 weeks and Group 2 (late closure) between 8 and 10 weeks. The primary outcome was expressed as the presence of anastomotic leak, obstruction, perforation, wound infection, sepsis, and death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A cohort of 31 patients with 16 patients in Group 1 and 15 in Group 2 were studied. The mean duration between ostomy creation and reversal was 5.1 \u00b1 0.63 weeks in Group 1 and 8.9 \u00b1 0.66 weeks in Group 2. The mean weight at reversal was 1435.5 \u00b1 163.8 g for patients in Group 1 and 1405 \u00b1 99.93 g for patients in Group 2. Weight gain at 90 days in Group 1 was 895 \u00b1 85.2 g and in Group 2 was 455 \u00b1 34.6 g, which was statistically significant (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.00001). Parenteral nutrition, ability to reach full enteral nutrition, and total ventilator days, mortality rate, and complications were not statistically different between the groups. The overall survival rate was 87.27%.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Ileostomy reversal at a lower weight and within 6 weeks was not associated with an increased risk of complications. Early stoma reversal may help in weight gain.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_369_20","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T10:16:51Z","timestamp":1716545811000},"page":"204-208","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["The Outcome of Late versus Early Ileostomy Closure at Low Body Weight (&lt;1500 g) in Babies with Necrotizing Enterocolitis"],"prefix":"10.4103","volume":"27","author":[{"given":"Pradyumna","family":"Pan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-15-20240905","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1053\/j.sempedsurg.2008.02.005","article-title":"Neonatal necrotizing enterocolitis","volume":"17","author":"Henry","year":"2008","journal-title":"Semin Pediatr 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