{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:26:10Z","timestamp":1787765170891,"version":"build-2784847793"},"reference-count":31,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study aims to compare the outcome of neonatal left congenital diaphragmatic hernia (CDH, Bochdalek type) repair through laparotomy with and without abdominal muscle closure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>This retrospective study was conducted between January 2012 and May 2021 at a neonatal surgical unit of a Tertiary Care Center. Demographic details, preoperative management, Two-dimensional-echo, intra-operative findings, postoperative course, and follow-up data were collected and analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The study group comprised 50 neonates with a mean standard deviation (SD) age at admission: 4.44 (5.12) days, male: female ratio of 3:2, and mean (SD) weight: 2.73 (0.51) kg. Following repair of the diaphragmatic defect through laparotomy, 26 (52%) underwent skin closure alone, whereas 24 (48%) underwent abdominal muscle closure. Postoperatively, there was a significant fall in the level of platelets (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.021), increase in pressure support by at least 4\u20135 cm H\n                      <jats:sub>2<\/jats:sub>\n                      O (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.027), and increase in the blood urea (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001), creatinine (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.005), lactate (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.019), and acidosis (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.048) in the muscle closure group. Although not statistically significant, there was a fall in the urine output and blood pressure in this group. There was no significant difference in the duration of inotropes. Mortality was 8 (32%) in the skin closure group, and 14 (61%) in the muscle closure group (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>Neonates undergoing left CDH repair through the abdominal route with skin closure alone, had better survival, as well as hematological, renal, and ventilatory parameters than those who underwent muscle closure. It is a useful surgical modification to improve outcome in centers with limited facilities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_37_23","type":"journal-article","created":{"date-parts":[[2024,1,17]],"date-time":"2024-01-17T14:01:06Z","timestamp":1705500066000},"page":"43-50","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of the Surgical Outcomes in Neonates with Left-sided Congenital Diaphragmatic Hernia with Only Skin Closure versus Abdominal Muscle Closure"],"prefix":"10.4103","volume":"29","author":[{"given":"Sravanthi","family":"Vutukuru","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, Advanced Pediatric Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prema","family":"Menon","sequence":"additional","affiliation":[{"name":"Department of 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