{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:39:16Z","timestamp":1787841556082,"version":"build-2784847793"},"reference-count":7,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:p>Diffuse esophageal leiomyomatosis (DEL) is a rare condition characterized by the growth of multiple benign smooth muscle tumors (leiomyomas) in the esophagus. These tumors can cause obstruction and functional impairment of the esophagus, leading to symptoms such as difficulty swallowing, chest pain, and weight loss. The disease can present with leiomyomas or glomerular nephropathy in other body parts, hearing defects, astigmatism, or myopia (Alport\u2019s syndrome). However, isolated cases are also reported in the literature. Surgical management of DEL presents several challenges due to the location and extent of the tumors. Herein, we describe a girl afflicted with DEL and required multiple surgeries for management, highlighting the unique challenges faced by the surgical team in restoring esophageal function and improving the patient\u2019s quality of life.<\/jats:p>","DOI":"10.4103\/jiaps.jiaps_47_24","type":"journal-article","created":{"date-parts":[[2024,8,23]],"date-time":"2024-08-23T22:18:21Z","timestamp":1724451501000},"page":"549-553","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Diffuse Esophageal Leiomyomatosis and the Surgical Challenges Encountered"],"prefix":"10.4103","volume":"29","author":[{"given":"Tanvi","family":"Luthra","sequence":"first","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sachit","family":"Anand","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjan Kumar","family":"Dhua","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devendra","family":"Yadav","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vishesh","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabudh","family":"Goel","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devasenathipathy","family":"Kandasamy","sequence":"additional","affiliation":[{"name":"Department of Radiodiagnosis, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandeep","family":"Agarwala","sequence":"additional","affiliation":[{"name":"Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohan","family":"Malik","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, All India Institute of Medical Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,8,23]]},"reference":[{"key":"R1-20240909","doi-asserted-by":"crossref","first-page":"e29","DOI":"10.1016\/j.jpedsurg.2005.02.016","article-title":"Familial massive leiomyoma with esophageal leiomyomatosis:An unusual presentation in a father and his 2 daughters","volume":"40","author":"Lee","year":"2005","journal-title":"J Pediatr Surg"},{"key":"R2-20240909","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1007\/s11605-008-0701-x","article-title":"Leiomyomatosis of the esophagus:Experience over a decade","volume":"13","author":"Gupta","year":"2009","journal-title":"J Gastrointest Surg"},{"key":"R3-20240909","doi-asserted-by":"crossref","first-page":"2166","DOI":"10.1002\/1097-0142(197611)38:5<2166::AID-CNCR2820380547>3.0.CO;2-B","article-title":"Leiomyomata of the esophagus. An analysis of 838 cases","volume":"38","author":"Seremetis","year":"1976","journal-title":"Cancer"},{"key":"R4-20240909","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1055\/s-0038-1676507","article-title":"Diffuse esophageal leiomyomatosis in pediatric patients:A systematic review and quality of evidence assessment","volume":"29","author":"Ziogas","year":"2019","journal-title":"Eur J Pediatr Surg"},{"key":"R5-20240909","doi-asserted-by":"crossref","first-page":"47","DOI":"10.4103\/1817-1737.58960","article-title":"Thoracoscopic enucleation of esophageal leiomyoma in patient with MEN I syndrome","volume":"5","author":"Saleh","year":"2010","journal-title":"Ann Thorac Med"},{"key":"R6-20240909","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1016\/j.jpedsurg.2020.04.017","article-title":"Gastric pull-up by the retrosternal route for esophageal replacement:Feasibility in a limited-resource scenario","volume":"56","author":"Acharya","year":"2021","journal-title":"J Pediatr Surg"},{"key":"R8-20240909","first-page":"00171","article-title":"Esophageal Reconstruction by Substernal Route:Impact of the Thoracic Inlet Enlargement on Cervical Anastomotic Complications:Leak and Stricture","volume":"5","author":"Abdelkader","year":"2016","journal-title":"Gastroenterol Hepatol"}],"container-title":["Journal of Indian Association of Pediatric Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_47_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:01:01Z","timestamp":1787839261000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.jiaps_47_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,23]]},"references-count":7,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jiaps.jiaps_47_24","relation":{},"ISSN":["0971-9261","1998-3891"],"issn-type":[{"value":"0971-9261","type":"print"},{"value":"1998-3891","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,23]]},"assertion":[{"value":"2024-03-09","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-05-02","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}