{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:20:04Z","timestamp":1787775604747,"version":"build-2784847793"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"ABSTRACT<\/jats:title>\n \n Aims:<\/jats:title>\n This study aims to determine the etiology of antenatal hydronephrosis (ANH) and predict need for surgical intervention based on antenatal renal pelvis anteroposterior diameter (APD).<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n Combined prospective and retrospective study (2012\u20132018) of ANH cases with postnatal follow-up. Surgical intervention was correlated with the degree of hydronephrosis (HDN) and pelvis APD measured at the 2\n nd<\/jats:sup>\n trimester, 3\n rd<\/jats:sup>\n trimester, and postnatal 6-week follow-up.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n One hundred and sixty-five patients were studied with a total of 219 ANH units. Transient HDN was seen in 116 units. Surgical intervention included pyeloplasty (\n n<\/jats:italic>\n = 76), sub ureteric dextranomer injection (\n n<\/jats:italic>\n = 8) and nephrectomy (\n n<\/jats:italic>\n = 1). Chances of requiring surgery based on the degree of HDN in 2\n nd<\/jats:sup>\n and 3\n rd<\/jats:sup>\n trimester respectively were mild: 11.32% and 9.52%, moderate: 34.21% and 37.03% and severe: 85.71% and 86.27%. The mean increase in APD between the 2\n nd<\/jats:sup>\n and 3\n rd<\/jats:sup>\n trimester (\n n<\/jats:italic>\n = 50) was lesser in conservatively managed (3.548 \u00b1 4.219 mm) than surgically managed (8.261 \u00b1 5.857 mm) patients (\n P<\/jats:italic>\n = 0.002). In another subset (\n n<\/jats:italic>\n = 37), the mean increase in APD between the 2\n nd<\/jats:sup>\n trimester and postnatal period was less in conservatively managed (1.432 \u00b1 0.612 mm) (\n P<\/jats:italic>\n = 0.088) than surgically managed patients (12.91 \u00b1 3.247 mm) (\n P<\/jats:italic>\n = 0.004). The area under the receiver operating characteristic (ROC) curve showed that an APD of 8.2 mm in the 2\n nd<\/jats:sup>\n trimester and 12.85 mm in the 3\n rd<\/jats:sup>\n trimester correlated with the requirement of postnatal surgery.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n Apart from the degree of HDN, significant changes in APD between 2\n nd<\/jats:sup>\n and 3\n rd<\/jats:sup>\n trimester and cut off value suggested by the ROC curve will help during antenatal counseling with regard to requirement of postnatal surgery.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_65_21","type":"journal-article","created":{"date-parts":[[2024,5,24]],"date-time":"2024-05-24T10:15:56Z","timestamp":1716545756000},"page":"333-339","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Outcome of Patients with Antenatally Diagnosed hydronephrosis with Respect to Postnatal Diagnosis and Need for Surgical Intervention"],"prefix":"10.4103","volume":"27","author":[{"given":"Sandeep Singh","family":"Sen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prema","family":"Menon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muneer Abbas","family":"Malik","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kushaljit Singh","family":"Sodhi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R2-11-20240905","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1016\/0002-9378(91)90099-D","article-title":"Congenital hydronephrosis: Correlation of fetal ultrasonographic findings with infant outcome","volume":"165","author":"Corteville","year":"1991","journal-title":"Am J Obstet Gynecol"},{"key":"R3-11-20240905","doi-asserted-by":"crossref","first-page":"F135","DOI":"10.1136\/fn.80.2.F135","article-title":"Prospective study of outcome in antenatally diagnosed renal pelvis dilatation","volume":"80","author":"Jaswon","year":"1999","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"R4-11-20240905","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1046\/j.1464-4096.2001.woodward.2578.x","article-title":"Postnatal management of antenatal hydronephrosis","volume":"89","author":"Woodward","year":"2002","journal-title":"BJU Int"},{"key":"R5-11-20240905","doi-asserted-by":"crossref","first-page":"1253","DOI":"10.1007\/s00467-005-1989-3","article-title":"Postnatal management of infants with antenatally detected hydronephrosis","volume":"20","author":"Aksu","year":"2005","journal-title":"Pediatr Nephrol"},{"key":"R6-11-20240905","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1542\/peds.2006-0120","article-title":"ANH as a predictor of postnatal outcome: A meta-analysis","volume":"118","author":"Lee","year":"2006","journal-title":"Pediatrics"},{"key":"R7-11-20240905","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1016\/j.jpurol.2010.09.007","article-title":"The predictive value of the first postnatal ultrasound in children with antenatal hydronephrosis","volume":"7","author":"Passerotti","year":"2011","journal-title":"J Pediatr Urol"},{"key":"R8-11-20240905","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1002\/uog.1879","article-title":"Outcome of fetal renal pelvic dilatation diagnosed during the third trimester","volume":"25","author":"Wollenberg","year":"2005","journal-title":"Ultrasound Obstet Gynecol"},{"key":"R9-11-20240905","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1148\/radiology.160.3.3526402","article-title":"Urinary tract dilatation in utero: Classification and clinical applications","volume":"160","author":"Grignon","year":"1986","journal-title":"Radiology"},{"key":"R10-11-20240905","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1046\/j.1469-0705.2001.00333.x","article-title":"Natural history of fetal hydronephrosis diagnosed on mid-trimester ultrasound","volume":"17","author":"Sairam","year":"2001","journal-title":"Ultrasound Obstet Gynecol"},{"key":"R11-11-20240905","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1259\/bjr.72.855.10396216","article-title":"The four year outcome following the demonstration of bilateral renal pelvic dilatation on prenatal renal ultrasound","volume":"72","author":"Broadley","year":"1999","journal-title":"Br J Radiol"},{"key":"R12-11-20240905","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.1016\/j.urology.2012.01.007","article-title":"Diagnostic value of anteroposterior diameter of fetal renal pelvis during second and third trimesters in predicting postnatal surgery among Korean population: Useful information for antenatal counseling","volume":"79","author":"Kim","year":"2012","journal-title":"Urology"},{"key":"R13-11-20240905","doi-asserted-by":"crossref","first-page":"724","DOI":"10.1016\/j.juro.2006.03.079","article-title":"The magnitude of fetal renal pelvic dilatation can identify obstructive postnatal hydronephrosis, and direct postnatal evaluation and management","volume":"176","author":"Coplen","year":"2006","journal-title":"J Urol"},{"key":"R14-11-20240905","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1016\/j.urology.2007.01.062","article-title":"Antenatal hydronephrosis and the risk of pyelonephritis hospitalization during the first year of life","volume":"69","author":"Walsh","year":"2007","journal-title":"Urology"},{"key":"R15-11-20240905","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1148\/radiology.187.1.8451404","article-title":"Incidental vesicoureteral reflux in neonates with antenatally detected hydronephrosis and other renal abnormalities","volume":"187","author":"Zerin","year":"1993","journal-title":"Radiology"},{"key":"R16-11-20240905","doi-asserted-by":"crossref","first-page":"490","DOI":"10.1016\/S0022-5347(17)38793-1","article-title":"Coexisting ureteropelvic junction obstruction and vesicoureteric reflux: Diagnostic and therapeutic indication","volume":"142","author":"Hollowell","year":"1989","journal-title":"J Urol"},{"key":"R17-11-20240905","doi-asserted-by":"crossref","first-page":"109","DOI":"10.4103\/jiaps.JIAPS_37_18","article-title":"Co-existing pediatric ureteropelvic junction obstruction and vesicoureteric reflux: Prevalence and implications","volume":"24","author":"Hegde","year":"2019","journal-title":"J Indian Assoc Pediatr Surg"}],"container-title":["Journal of Indian Association of Pediatric Surgeons"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.JIAPS_65_21","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:35:01Z","timestamp":1787772901000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jiaps.JIAPS_65_21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,5]]},"references-count":16,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022]]}},"URL":"https:\/\/doi.org\/10.4103\/jiaps.jiaps_65_21","relation":{},"ISSN":["0971-9261"],"issn-type":[{"value":"0971-9261","type":"print"}],"subject":[],"published":{"date-parts":[[2022,5]]}}}