{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:19:03Z","timestamp":1787840343545,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>\n                    A\n                    <jats:sc>BSTRACT<\/jats:sc>\n                  <\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction:<\/jats:title>\n                    <jats:p>Primary hyperparathyroidism (PHPT) is a rare disorder in children, predominantly caused by parathyroid adenoma, often leading to delayed diagnosis and significant morbidity.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Subjects and Methods:<\/jats:title>\n                    <jats:p>A prospective analysis of children with PHPT secondary to parathyroid adenoma, study period from 2015 to 2024 at a single institution. Data evaluated included demographics, clinical manifestations, biochemical and radiological features, surgical interventions, and postoperative care.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Six children (4 males, and 2 females) with a mean age of 13.8 years (range 7\u201317) were evaluated. The mean duration from symptom onset to diagnosis was 3 years. All children presented with musculoskeletal deformities and exhibited elevated serum calcium (mean 12.48 mg\/dL) and serum parathyroid hormone levels (1789\u20132500 picograms per milliliter (pg\/mL)). Imaging with ultrasonogram and Isotope scan was successful in confirming the location of parathyroid adenoma with 100% sensitivity. Surgical excision was successful, and all patients developed hungry bone syndrome, requiring calcium supplementation. The mean serum calcium at discharge was 8.68 mg\/dL, with no recurrence noted during an average follow-up of 9 years.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion:<\/jats:title>\n                    <jats:p>Pediatric PHPT necessitates a high index of suspicion for timely diagnosis and intervention to prevent development of permanent disabilities. Effective surgical management and postoperative care can significantly enhance patient outcomes.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jiaps.jiaps_71_25","type":"journal-article","created":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T10:00:14Z","timestamp":1750154414000},"page":"595-599","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Clinical Insights and Surgical Management of Pediatric Parathyroid Adenoma: Outcomes and Challenges"],"prefix":"10.4103","volume":"30","author":[{"given":"A.","family":"Manasa","sequence":"first","affiliation":[{"name":"Department of Pediatric Surgery, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gowri","family":"Shankar","sequence":"additional","affiliation":[{"name":"Department of Pediatric Surgery, Indira Gandhi Institute of Child Health, Bengaluru, Karnataka, 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elevated parathyroid hormone levels after successful parathyroidectomy for sporadic primary hyperparathyroidism","volume":"143","author":"Solorzano","year":"2008","journal-title":"Arch Surg"}],"container-title":["Journal of Indian Association of Pediatric 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