{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T19:30:58Z","timestamp":1786649458431,"version":"build-2736575974"},"reference-count":36,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:sec>\n                    <jats:title>Aims:<\/jats:title>\n                    <jats:p>The study was aimed to evaluate the effect of prosthodontic rehabilitation on psychological status (PS) and quality of life (QoL) in maxillectomy patients of coronavirus disease 2019-associated mucormycosis (CAM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings and Design:<\/jats:title>\n                    <jats:p>The study was designed as a prospective and clinical study.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Twenty-four CAM patients undergoing maxillectomy and subsequent prosthetic rehabilitation were included. The treatment involved surgical, intermediate, and definitive obturator delivery at various phases of healing. PS was assessed using the Hospital Anxiety and Depression Scale (HADS), QOL using the European Organization for Research and Treatment of Cancer QoL Questionnaire-Head and Neck Module (EORTC QLQ-HandN35), and the functioning of obturator was assessed utilising the Obturator Functioning Scale (OFS) at various time points: before maxillectomy (T1), 2 weeks after maxillectomy (T2), 2 weeks upon usage of intermediate obturator (T3), just before delivery of definitive obturator (T4), and 12 weeks after the usage of definitive obturator (T5).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Analysis Used:<\/jats:title>\n                    <jats:p>\n                      Data were analyzed using a social science statistical analysis program (Stata 14.0; StataCorp LLC, Texas, USA). The significance level was chosen &lt;0.05. Shapiro\u2013Wilk test was used to assess the normality of quantitative data. Student\u2019s\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test was employed (\u03b1 =0.05) to evaluate if the patient\u2019s PS, QOL, and obturator function had changed over time. The Spearman correlation coefficient (\u03b1 =0.05) was utilized to evaluate the correlation coefficient between PS, QOL, and obturator function seen at T3 and T5.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Out of 24 enrolled patients, nine were dropped out. HADS-anxiety score was the highest at T1 (18.6 \u00b1 1.2) and HADS-depression score was the highest at T2 (18.8 \u00b1 1.6). HADS scores decreased significantly (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001) after prosthetic rehabilitation. EORTC QLQ-HandN35 score was the highest at T2 (105.8 \u00b1 29.5), with statistical significance (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.001) after rehabilitation. OFS was the highest at T3 (51.9 \u00b1 3.9) and lowest at T5 (25.4 \u00b1 2.8).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>CAM and maxillectomy deliberately affects the PS and QOL. Prosthetic rehabilitation, psychological motivation, and education create greater improvement in PS and QOL. The progress in parameters showed an upward trend with good obturator quality over a period of time.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jips.jips_156_24","type":"journal-article","created":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T03:00:27Z","timestamp":1728961227000},"page":"351-358","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Impact of prosthodontic rehabilitation on psychological status and quality of life in maxillectomy patients of coronavirus disease 2019-associated mucormycosis at a tertiary care center: A prospective clinical study"],"prefix":"10.4103","volume":"24","author":[{"given":"P.","family":"Vijayabharathi","sequence":"first","affiliation":[{"name":"Department of Dentistry, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surabhi Rambhau","family":"Somkuwar","sequence":"additional","affiliation":[{"name":"Department of Dentistry, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santhosh","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Dentistry, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virat","family":"Galhotra","sequence":"additional","affiliation":[{"name":"Department of Dentistry, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Uvashri","family":"Selvaraj","sequence":"additional","affiliation":[{"name":"Unit of Prosthodontics, Postgraduate Institute of Medical Education and Research, Chandigarh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,10,15]]},"reference":[{"key":"R1-20260427","doi-asserted-by":"crossref","first-page":"265","DOI":"10.3390\/jof6040265","article-title":"Epidemiology and diagnosis of mucormycosis: An update","volume":"6","author":"Skiada","year":"2020","journal-title":"J Fungi (Basel)"},{"key":"R2-20260427","doi-asserted-by":"crossref","first-page":"244","DOI":"10.4103\/ijo.IJO_3774_20","article-title":"Mucor in a viral land: A tale of two pathogens","volume":"69","author":"Sen","year":"2021","journal-title":"Indian J Ophthalmol"},{"key":"R3-20260427","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1111\/myc.13335","article-title":"ECMM\/ISHAM recommendations for clinical management of COVID-19 associated mucormycosis in low-and middle-income countries","volume":"64","author":"Rudramurthy","year":"2021","journal-title":"Mycoses"},{"key":"R4-20260427","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1016\/j.cmi.2023.03.008","article-title":"COVID-19-associated mucormycosis: A systematic review and meta-analysis of 958 cases","volume":"29","author":"\u00d6zbek","year":"2023","journal-title":"Clin Microbiol Infect"},{"key":"R5-20260427","doi-asserted-by":"crossref","first-page":"373","DOI":"10.1007\/s12663-021-01604-2","article-title":"Current understanding in the pathophysiology of SARS-CoV-2-associated rhino-orbito-cerebral mucormycosis: A comprehensive review","volume":"20","author":"Jose","year":"2021","journal-title":"J Maxillofac Oral Surg"},{"key":"R6-20260427","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1007\/s12663-021-01532-1","article-title":"SARS-CoV-2, uncontrolled diabetes and corticosteroids-An unholy trinity in invasive fungal infections of the maxillofacial region? 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