{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T14:32:33Z","timestamp":1787841153384,"version":"build-2784847793"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,4]]},"abstract":"\n Aim:<\/jats:title>\n To compare the effect of internal hexagonal and internal conical implant-abutment connection (IAC) on peri-implant hard and soft tissues.<\/jats:p>\n <\/jats:sec>\n \n Settings and Design:<\/jats:title>\n Parallel arm, randomized controlled trial.<\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n A total of 44 participants requiring rehabilitation with single implant-supported crown in the posterior region were enrolled and randomly allocated to two groups (\n n<\/jats:italic>\n = 22). Participants in Group 1 were rehabilitated with implants with internal hexagonal IAC while in Group 2 with implants having internal conical IAC. Following delayed loading protocol, implants were restored with single implant-supported crown and baseline data along with subsequent follow up data at 3\n rd<\/jats:sup>\n , 6\n th<\/jats:sup>\n , and 12\n th<\/jats:sup>\n months after occlusal loading were recorded.\n <\/jats:p>\n <\/jats:sec>\n \n Statistical Analysis Used:<\/jats:title>\n \n Data were analyzed using the Statistical Packages for Social Sciences (SPSS) version 29.0. Categorical variables were represented as counts\/percentages, whereas continuous variables were denoted as mean \u00b1 standard deviation. Unpaired\n t<\/jats:italic>\n -tests and Chi-square tests were used for group comparisons.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n At 12 months, crestal bone loss was lower in the internal conical group (0.78 \u00b1 0.03 mm) than the internal hexagonal group (0.81 \u00b1 0.02 mm;\n P<\/jats:italic>\n < 0.001). Probing depth was consistently shallower in the internal conical group (3.17 \u00b1 0.09 mm vs. 3.47 \u00b1 0.17 mm;\n P<\/jats:italic>\n < 0.001). Interleukin-1\u03b2 levels were significantly lower in the internal conical group across all time points, with large effect sizes.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Internal conical IAC showed lower inflammation, improved bone preservation, and shallower probing depths compared to internal hexagonal IAC. Despite small structural effect sizes, the inflammatory response indicated a meaningful biological advantage. Both IAC remain viable, with selection guided by patient-specific needs and long-term outcomes.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jips.jips_248_25","type":"journal-article","created":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T06:00:48Z","timestamp":1775023248000},"page":"160-167","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A comparative evaluation of peri-implant soft and hard tissues between internal hexagonal and internal conical type of implant-abutment connection: A randomized controlled trial"],"prefix":"10.4103","volume":"26","author":[{"given":"Aditi","family":"Mishra","sequence":"first","affiliation":[{"name":"Department of Prosthodontics, Maulana Azad Institute of Dental Sciences, New Delhi, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramashanker","family":"Siddharth","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Crown and Bridge, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balendra Pratap","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Crown and Bridge, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamleshwar","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Crown and Bridge, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mayank","family":"Singh","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Crown and Bridge, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooran","family":"Chand","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics, Crown and Bridge, Faculty of Dental Sciences, King George's Medical University, Lucknow, Uttar Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,4,1]]},"reference":[{"key":"R1-20260416","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1111\/j.1600-0501.2007.01453.x","article-title":"A systematic review of the 5-year survival and complication rates of implant-supported single crowns","volume":"19","author":"Jung","year":"2008","journal-title":"Clin Oral Implants Res"},{"key":"R2-20260416","first-page":"212","article-title":"Cemented single crowns on osseointegrated implants after 5 years: Results from a prospective study on CeraOne","volume":"11","author":"Andersson","year":"1998","journal-title":"Int J Prosthodont"},{"key":"R3-20260416","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1902\/jop.2002.73.3.322","article-title":"The causes of early implant bone loss: Myth or science?","volume":"73","author":"Oh","year":"2002","journal-title":"J Periodontol"},{"key":"R4-20260416","doi-asserted-by":"crossref","first-page":"349","DOI":"10.11138\/orl\/2017.10.4.349","article-title":"Implant-abutment connections on single crowns: A systematic review","volume":"10","author":"Ceruso","year":"2017","journal-title":"Oral Implantol (Rome)"},{"key":"R5-20260416","doi-asserted-by":"crossref","first-page":"814","DOI":"10.1111\/cid.12651","article-title":"The micromechanical behavior of implant-abutment connections under a dynamic load protocol","volume":"20","author":"Zipprich","year":"2018","journal-title":"Clin Implant Dent Relat Res"},{"key":"R6-20260416","first-page":"1","article-title":"Osseointegrated implants in the treatment of the edentulous jaw. 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