{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T14:01:05Z","timestamp":1790863265328,"version":"4.1.0"},"reference-count":28,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T00:00:00Z","timestamp":1790812800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,10]]},"abstract":"Abstract<\/jats:title>\n \n Aim:<\/jats:title>\n This study aimed to compare the marginal and internal adaptation of monolithic computer-aided design and computer-aided manufacturing (CAD\/CAM) zirconia crowns and heat-pressed ceramic-veneered zirconia crowns fabricated using a standardized digital workflow.<\/jats:p>\n <\/jats:sec>\n \n Settings and Design:<\/jats:title>\n \n An\n in vitro<\/jats:italic>\n laboratory study was conducted using standardized epoxy resin dies and zirconia crowns fabricated by two different laboratory workflows.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n Twenty zirconia crowns were fabricated from a single STL dataset with a 50-\u00b5m cement space and divided into two groups (\n n<\/jats:italic>\n = 10): monolithic CAD\/CAM zirconia (MZ) and bilayer heat-pressed ceramic-on-zirconia (PVZ). All crowns were fabricated on epoxy resin dies replicated from a CAD\/CAM-milled stainless-steel master die. After cementation with glass ionomer cement under a controlled seating load of 50 N, the specimens were sectioned buccolingually. Marginal and internal gaps were measured using scanning electron microscopy at eight predetermined sites.\n <\/jats:p>\n <\/jats:sec>\n \n Statistical Analysis Used:<\/jats:title>\n \n Data were evaluated for normality using the Shapiro\u2013Wilk test. Intergroup comparisons were performed using the Mann\u2013Whitney U-test, with statistical significance set at\n P<\/jats:italic>\n < 0.05. Bonferroni adjustment was applied for exploratory multiple comparisons.\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n \n For the primary outcome, composite internal adaptation was lower in the monolithic CAD\/CAM zirconia crown group than in the heat-pressed ceramic-veneered zirconia crown group (103.07 vs. 111.38 \u00b5m;\n P<\/jats:italic>\n = 0.019), with a moderate effect size (\n r<\/jats:italic>\n = 0.53). Composite marginal adaptation did not differ significantly between the groups (88.90 vs. 95.73 \u00b5m;\n P<\/jats:italic>\n = 0.226).\n <\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n Both fabrication workflows produced zirconia crowns with marginal and internal adaptations within clinically acceptable limits. Monolithic CAD\/CAM zirconia crowns showed slightly smaller internal discrepancies than heat-pressed ceramic-veneered zirconia crowns; however, the magnitude of this difference is unlikely to affect clinical seating or cementation.<\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jips.jips_289_26","type":"journal-article","created":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T10:01:03Z","timestamp":1790848863000},"page":"397-404","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Marginal and internal adaptation of monolithic computer-aided design and computer-aided manufacturing zirconia crowns and heat-pressed ceramic veneered zirconia crowns: An in vitro study"],"prefix":"10.4103","volume":"26","author":[{"given":"Smruti","family":"Nanda","sequence":"first","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirna","family":"Garhnayak","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhijita","family":"Mohapatra","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sangram","family":"Panda","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhilash","family":"Mohapatra","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopal Krishna","family":"Choudhury","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha \u2018O\u2019 Anusandhan (Deemed to be) University, Bhubaneswar, Odisha, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2026,10,1]]},"reference":[{"key":"R1-20261001","doi-asserted-by":"crossref","first-page":"4956","DOI":"10.1016\/j.jmrt.2019.06.043","article-title":"Zirconia in dental prosthetics: A literature review","volume":"8","author":"Grech","year":"2019","journal-title":"J Mater Res Technol"},{"key":"R2-20261001","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1038\/s41415-024-7616-0","article-title":"Emerging trends and clinical recommendations for zirconia ceramic crowns: A concise review","volume":"237","author":"Vijan","year":"2024","journal-title":"Br Dent J"},{"key":"R3-20261001","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/s41405-024-00214-7","article-title":"Fifteen-year recall period on zirconia-based single crowns and fixed dental prostheses. A prospective observational study","volume":"10","author":"Khijmatgar","year":"2024","journal-title":"BDJ Open"},{"key":"R4-20261001","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1186\/s12903-025-05947-x","article-title":"Marginal and internal adaptation and absolute marginal discrepancy of 3D-printed, milled, and prefabricated crowns for primary molar teeth: An in vitro comparative study","volume":"25","author":"Akta\u015f","year":"2025","journal-title":"BMC Oral Health"},{"key":"R5-20261001","first-page":"2029","article-title":"Comparison of marginal adaptation and internal fit of monolithic lithium disilicate crowns produced by four different CAD\/CAM systems","volume":"25","author":"Duarte","year":"2020","journal-title":"Clin Oral Investig"},{"key":"R6-20261001","doi-asserted-by":"crossref","first-page":"54","DOI":"10.4103\/njcp.njcp_410_23","article-title":"Evaluation of marginal and internal adaptation of crowns fabricated with three different zirconia CAD\/CAM 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