{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T20:42:57Z","timestamp":1786653777601,"version":"build-2736575974"},"reference-count":50,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Aim:<\/jats:title>\n                    <jats:p>This study aimed to systematically review the frequency and type of intraoral prosthetic rehabilitation in patients with rhino-orbital-cerebral-mucormycosis (ROCM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Settings and Design:<\/jats:title>\n                    <jats:p>Systematic review following Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>An electronic search was conducted in databases including PubMed, Web of Science, Scopus, and Google Scholar. Case reports that documented prosthetic rehabilitation following surgery in patients with ROCM were included. This review was registered under the International Prospective Register of Systematic Reviews CRD42021262284. Assessment of the quality of the included studies was done using the Joanna Briggs Institute Critical Appraisal Checklist for Case reports, which comprised of an eight-item checklist. The recorded observations were organized and subjected to analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Statistical Analysis Used:<\/jats:title>\n                    <jats:p>Qualitative analysis was used.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Among the 25 case reports, type IId defect was the most common. Three types of prosthetic treatments were rendered, with the obturator being the most common choice of rehabilitation, followed by implant-retained obturator overdenture and fixed implant-supported prosthesis. Patients undergoing implant-based rehabilitation exhibited a 100% survival rate for implants, with follow-up periods spanning from 6 months to 3 years. No prosthetic complications were reported in any of the included case reports.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The prevailing defect type identified was IId (48%), while the treatment of choice most frequently employed was an obturator (84%). However, with limited evidence available at present, further research is required to draw more definitive conclusions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jips.jips_305_23","type":"journal-article","created":{"date-parts":[[2024,8,8]],"date-time":"2024-08-08T12:54:03Z","timestamp":1723121643000},"page":"36-45","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Prosthetic rehabilitation of intraoral defects in patients with rhino-orbital-cerebral-mucormycosis: A systematic review"],"prefix":"10.4103","volume":"24","author":[{"given":"Samiksha","family":"Wadhwa","sequence":"first","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Christian Dental College, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit Sunny","family":"Mathew","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Christian Dental College, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Angleena Y.","family":"Daniel","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Christian Dental College, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirmal","family":"Kurian","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Christian Dental College, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin George","family":"Varghese","sequence":"additional","affiliation":[{"name":"Department of Prosthodontics and Crown and Bridge, Christian Dental College, Ludhiana, Punjab, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,1,24]]},"reference":[{"key":"R1-20260504","doi-asserted-by":"crossref","first-page":"e405","DOI":"10.1016\/S1473-3099(19)30312-3","article-title":"Global guideline for the diagnosis and management of mucormycosis: An initiative of the European confederation of medical mycology in cooperation with the mycoses study group education and research consortium","volume":"19","author":"Cornely","year":"2019","journal-title":"Lancet Infect Dis"},{"key":"R2-20260504","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1128\/CMR.13.2.236","article-title":"Zygomycetes in human disease","volume":"13","author":"Ribes","year":"2000","journal-title":"Clin Microbiol Rev"},{"key":"R3-20260504","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1055\/s-2008-1063850","article-title":"Pulmonary zygomycosis","volume":"29","author":"Pyrgos","year":"2008","journal-title":"Semin Respir Crit Care Med"},{"key":"R4-20260504","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1469-0691.2006.01604.x","article-title":"Mucormycosis: An emerging disease?","volume":"12","author":"Bouza","year":"2006","journal-title":"Clin Microbiol Infect"},{"issue":"Suppl 1","key":"R5-20260504","doi-asserted-by":"crossref","first-page":"S23","DOI":"10.1093\/cid\/cir866","article-title":"Epidemiology and clinical manifestations of mucormycosis","volume":"54","author":"Petrikkos","year":"2012","journal-title":"Clin Infect Dis"},{"issue":"Suppl 1","key":"R6-20260504","doi-asserted-by":"crossref","first-page":"S126","DOI":"10.1093\/clinids\/14.Supplement_1.S126","article-title":"Mucormycosis","volume":"14","author":"Sugar","year":"1992","journal-title":"Clin Infect Dis"},{"key":"R7-20260504","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/S0022-3913(82)80095-4","article-title":"Mucormycosis: Oral and prosthodontic implications. 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