{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T14:51:41Z","timestamp":1786719101972,"version":"build-2736575974"},"reference-count":41,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Indian Soc Periodontol"],"published-print":{"date-parts":[[2019]]},"DOI":"10.4103\/jisp.jisp_173_18","type":"journal-article","created":{"date-parts":[[2019,2,28]],"date-time":"2019-02-28T07:48:52Z","timestamp":1551340132000},"page":"100","source":"Crossref","is-referenced-by-count":5,"title":["Evaluation and comparison of Vitamin D receptors in periodontal ligament tissue of Vitamin D-deficient chronic periodontitis patients before and after supplementation of Vitamin D3"],"prefix":"10.4103","volume":"23","author":[{"given":"VishakhaSarang","family":"Patil","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"RohiniSalil","family":"Mali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"AlpanaSubodh","family":"Moghe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0972-124X.253305-1","first-page":"114","volume-title":"Extrarenal synthesis of 1,25 dihydroxyvitamin D and its health implications","author":"Bikle","year":"2009","journal-title":"Clin Rev Bone Min Metab"},{"key":"key-10.4103\/0972-124X.253305-2","first-page":"2754","volume-title":"Megalin-mediated endocytosis of Vitamin D binding protein correlates with 25-hydroxycholecalciferol actions in human mammary cells","author":"Rowling","year":"2006","journal-title":"J Nutr"},{"key":"key-10.4103\/0972-124X.253305-3","first-page":"552","volume-title":"Vitamin D and inflammation","author":"Guillot","year":"2010","journal-title":"Joint Bone Spine"},{"key":"key-10.4103\/0972-124X.253305-4","first-page":"63","volume-title":"1alpha, 25-dihydroxyvitamin D3 and a variety of its natural metabolites transcriptionally repress nuclear-factor-kappaB-mediated interleukin-8 gene expression","author":"Harant","year":"1997","journal-title":"Eur J Biochem"},{"key":"key-10.4103\/0972-124X.253305-5","first-page":"1359","volume-title":"Vitamin D: Emerging roles in infection and immunity","author":"Bartley","year":"2010","journal-title":"Expert Rev Anti Infect Ther"},{"key":"key-10.4103\/0972-124X.253305-6","first-page":"1188","volume-title":"Target cells for 1,25-dihydroxyvitamin D3 in intestinal tract, stomach, kidney, skin, pituitary, and parathyroid","author":"Stumpf","year":"1979","journal-title":"Science"},{"key":"key-10.4103\/0972-124X.253305-7","first-page":"e90301","volume-title":"Both 25-hydroxyvitamin-D3 and 1,25-dihydroxyvitamin-D3 reduces inflammatory response in human periodontal ligament cells","author":"Andrukhov","year":"2014","journal-title":"PLoS One"},{"key":"key-10.4103\/0972-124X.253305-8","first-page":"625","volume-title":"Osteogenic induction and 1,25-dihydroxyvitamin D3 oppositely regulate the proliferation and expression of RANKL and the Vitamin D receptor of human periodontal ligament cells","author":"Tang","year":"2009","journal-title":"Arch Oral Biol"},{"key":"key-10.4103\/0972-124X.253305-9","first-page":"2250","volume-title":"Vitamin D-mediated induction of innate immunity in gingival epithelial cells","author":"McMahon","year":"2011","journal-title":"Infect Immun"},{"key":"key-10.4103\/0972-124X.253305-10","first-page":"e39878","volume-title":"Characterization of the autocrine\/paracrine function of Vitamin D in human gingival fibroblasts and periodontal ligament cells","author":"Liu","year":"2012","journal-title":"PLoS One"},{"key":"key-10.4103\/0972-124X.253305-11","first-page":"26","volume-title":"Human articular chondrocytes acquire 1,25-(OH)2 vitamin D-3 receptors in culture","author":"Bhalla","year":"1987","journal-title":"Biochim Biophys Acta"},{"key":"key-10.4103\/0972-124X.253305-12","first-page":"700","volume-title":"Immunolocalization of calbindin D28k and Vitamin D receptor during root formation of murine molar teeth","author":"Onishi","year":"2003","journal-title":"Anat Rec A Discov Mol Cell Evol Biol"},{"key":"key-10.4103\/0972-124X.253305-13","first-page":"453","volume-title":"1\u03b1,25-dihydroxyvitamin D3 inhibits osteoblastic differentiation of mouse periodontal fibroblasts","author":"Chen","year":"2012","journal-title":"Arch Oral Biol"},{"key":"key-10.4103\/0972-124X.253305-14","first-page":"1080S","volume-title":"Vitamin D deficiency: A worldwide problem with health consequences","author":"Holick","year":"2008","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/0972-124X.253305-15","first-page":"729","volume-title":"Vitamin D deficiency in India: Prevalence, causalities and interventions","author":"Ritu","year":"2014","journal-title":"Nutrients"},{"key":"key-10.4103\/0972-124X.253305-16","first-page":"239","volume-title":"Vitamin D & bone mineral density of healthy school children in Northern India","author":"Marwaha","year":"2008","journal-title":"Indian J Med Res","ISSN":"https:\/\/id.crossref.org\/issn\/0971-5916","issn-type":"print"},{"key":"key-10.4103\/0972-124X.253305-17","first-page":"680","volume-title":"Vitamin D deficiency in rural girls and pregnant women despite abundant sunshine in Northern India","author":"Sahu","year":"2009","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key-10.4103\/0972-124X.253305-18","first-page":"755","volume-title":"Vitamin D deficiency in Indian adolescents","author":"Khadilkar","year":"2010","journal-title":"Indian Pediatr"},{"key":"key-10.4103\/0972-124X.253305-19","first-page":"55","volume-title":"Evaluation of 25(OH)D3 levels in chronic periodontitis and periodontally healthy subjects","author":"Patil","year":"2017","journal-title":"Int J Periodontol Implantol"},{"key":"key-10.4103\/0972-124X.253305-20","first-page":"195","volume-title":"Vitamin D status and periodontal disease among pregnant women","author":"Boggess","year":"2011","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.253305-21","first-page":"e24","volume-title":"Population-based 5-year follow-up study in Taiwan of osteoporosis and risk of periodontitis","author":"Chang","year":"2014","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.253305-22","first-page":"274","volume-title":"Low serum level of 1,25(OH)2 D is associated with chronic periodontitis","author":"Antonoglou","year":"2015","journal-title":"J Periodontal Res"},{"key":"key-10.4103\/0972-124X.253305-23","first-page":"89","volume-title":"Low Vitamin D status strongly associated with periodontitis in Puerto Rican adults","author":"Abreu","year":"2016","journal-title":"BMC Oral Health"},{"key":"key-10.4103\/0972-124X.253305-24","first-page":"4","volume-title":"Efficacy and safety of cholecalciferol supplementation in Vitamin D deficient subjects based on endocrine society clinical practice guidelines","author":"Harinarayan","year":"2012","journal-title":"Endocrinol Metabol Syndr"},{"key":"key-10.4103\/0972-124X.253305-25","first-page":"4709","volume-title":"Skeletal muscle strength in young Asian Indian females after Vitamin D and calcium supplementation: A double-blind randomized controlled clinical trial","author":"Goswami","year":"2012","journal-title":"J Clin Endocrinol Metab"},{"key":"key-10.4103\/0972-124X.253305-26","first-page":"694","volume-title":"The case against ergocalciferol (Vitamin D2) as a Vitamin supplement","author":"Houghton","year":"2006","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/0972-124X.253305-27","first-page":"981","volume-title":"Evaluation of ergocalciferol or cholecalciferol dosing, 1,600 IU daily or 50,000 IU monthly in older adults","author":"Binkley","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"key-10.4103\/0972-124X.253305-28","first-page":"854","volume-title":"Evidence that Vitamin D3 increases serum 25-hydroxyvitamin D more efficiently than does Vitamin D2","author":"Trang","year":"1998","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/0972-124X.253305-29","first-page":"5387","volume-title":"Vitamin D2 is much less effective than Vitamin D3 in humans","author":"Armas","year":"2004","journal-title":"J Clin Endocrinol Metab"},{"key":"key-10.4103\/0972-124X.253305-30","first-page":"E447","volume-title":"Vitamin D (3) is more potent than Vitamin D(2) in humans","author":"Heaney","year":"2011","journal-title":"J Clin Endocrinol Metab"},{"key":"key-10.4103\/0972-124X.253305-31","first-page":"649","volume-title":"The urgent need to recommend an intake of Vitamin D that is effective","author":"Vieth","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/0972-124X.253305-32","first-page":"6","volume-title":"Risk assessment for Vitamin D","author":"Hathcock","year":"2007","journal-title":"Am J Clin Nutr"},{"key":"key-10.4103\/0972-124X.253305-33","first-page":"445","volume-title":"Effect of cholecalciferol and calcium supplementation on muscle strength and energy metabolism in vitamin D-deficient Asian Indians: A randomized, controlled trial","author":"Gupta","year":"2010","journal-title":"Clin Endocrinol (Oxf)"},{"key":"key-10.4103\/0972-124X.253305-34","first-page":"173","volume-title":"Vitamin D discovery outpaces FDA decision making","author":"Marshall","year":"2008","journal-title":"Bioessays"},{"key":"key-10.4103\/0972-124X.253305-35","first-page":"757","volume-title":"Reversing bacteria-induced Vitamin D receptor dysfunction is key to autoimmune disease","author":"Waterhouse","year":"2009","journal-title":"Ann N Y Acad Sci"},{"key":"key-10.4103\/0972-124X.253305-36","unstructured":"Waterhouse JC, Marshall TG, Fenter B, Mangin M, Blaney G. High levels of active 1,25-dihydroxyvitamin D despite low levels of the 25-hydroxyvitamin D precursor-implications of dysregulated Vitamin D for diagnosis and treatment of chronic disease. In: Veronica D, editors. Vitamin D: New Research. Vol. 1. New York: Nova Science Publishers; 2006. p. 1-23."},{"key":"key-10.4103\/0972-124X.253305-37","first-page":"1686","volume-title":"1,25-dihydroxyvitamin D3 increases nuclear Vitamin D3 receptors by blocking ubiquitin\/proteasome-mediated degradation in human skin","author":"Li","year":"1999","journal-title":"Mol Endocrinol"},{"key":"key-10.4103\/0972-124X.253305-38","first-page":"e96695","volume-title":"Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+T cells","author":"Kongsbak","year":"2014","journal-title":"PLoS One"},{"key":"key-10.4103\/0972-124X.253305-39","first-page":"2203","volume-title":"Regulation of 1,25-dihydroxyvitamin D3 receptors by Vitamin D analogs in cultured mammalian cells","author":"Costa","year":"1985","journal-title":"Endocrinology"},{"key":"key-10.4103\/0972-124X.253305-40","first-page":"1844","volume-title":"Distinct, tissue-specific regulation of Vitamin D receptor in the intestine, kidney, and skin by dietary calcium and Vitamin D","author":"Zineb","year":"1998","journal-title":"Endocrinology"},{"key":"key-10.4103\/0972-124X.253305-41","first-page":"20082","volume-title":"Up-regulation of the Vitamin D receptor in response to 1,25-dihydroxyvitamin D3 results from ligand-induced stabilization","author":"Wiese","year":"1992","journal-title":"J Biol Chem"}],"container-title":["Journal of Indian Society of Periodontology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:43:51Z","timestamp":1786715031000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jisp.jisp_173_18"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019]]},"references-count":41,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2019]]}},"alternative-id":["253305"],"URL":"https:\/\/doi.org\/10.4103\/jisp.jisp_173_18","relation":{},"ISSN":["0972-124X"],"issn-type":[{"value":"0972-124X","type":"print"}],"subject":[],"published":{"date-parts":[[2019]]}}}