{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:28:04Z","timestamp":1787772484235,"version":"build-2784847793"},"reference-count":10,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The aim of the present study is to report a case of periodontal Ehlers\u2013Danlos syndrome (pEDS) in early childhood. A 3-year-old child, complaining of severe tooth mobility, gingival bleeding, and early loss of deciduous teeth sought the dental clinics. The patient was diagnosed with pEDS, and no other systematic health impairments were diagnosed. It was implemented a strict supragingival biofilm control, using mechanical and chemical strategies. However, during the treatment, the patient had to receive multiple dental extractions. Scaling and root planing were performed in the remaining teeth, and the patient is included in the periodontal maintenance program to prevent recurrence of the disease. It was concluded that, although rare, severe cases of periodontitis may occur in deciduous teeth. Strict supragingival biofilm control and periodontal maintenance are strongly recommended in those patients, along with familial monitoring.<\/jats:p>","DOI":"10.4103\/jisp.jisp_266_22","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T15:59:48Z","timestamp":1717084788000},"page":"99-103","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Periodontal Ehlers\u2013Danlos syndrome in early childhood: A case report of loss of deciduous teeth"],"prefix":"10.4103","volume":"27","author":[{"given":"Ricardo Souza","family":"Martins","sequence":"first","affiliation":[{"name":"Department of Dental Clinics, School of Pharmacy, Dentistry and Nursing, Federal University of Cear\u00e1, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Wilker Mustafa Gomes","family":"Muniz","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Federal University of Pelotas, Pelotas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juliana Oliveira","family":"Gondim","sequence":"additional","affiliation":[{"name":"Department of Dental Clinics, School of Pharmacy, Dentistry and Nursing, Federal University of Cear\u00e1, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lu\u00edsa De Souza","family":"Maurique","sequence":"additional","affiliation":[{"name":"School of Medicine, Lutheran University of Brazil, Canoas, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cl\u00e9lia Maria","family":"Nolasco-Lopes","sequence":"additional","affiliation":[{"name":"Department of Dental Clinics, School of Pharmacy, Dentistry and Nursing, Federal University of Cear\u00e1, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bibiana Mello De","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Programa De P\u00f3s-Gradua\u00e7\u00e3o Em Gen\u00e9tica E Biologia Molecular, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosimary De Sousa","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Department of Dental Clinics, School of Pharmacy, Dentistry and Nursing, Federal University of Cear\u00e1, Fortaleza, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,1,3]]},"reference":[{"issue":"Suppl 20","key":"R1-20240828","first-page":"S162","article-title":"Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45","author":"Papapanou","year":"2018","journal-title":"J Clin Periodontol"},{"issue":"Suppl 20","key":"R2-20240828","first-page":"S171","article-title":"Manifestations of systemic diseases and conditions that affect the periodontal attachment apparatus: Case definitions and diagnostic considerations","volume":"45","author":"Albandar","year":"2018","journal-title":"J Clin Periodontol"},{"key":"R3-20240828","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1111\/prd.12072","article-title":"Periodontal disease in children and adolescents of Latin America","volume":"67","author":"Botero","year":"2015","journal-title":"Periodontol 2000"},{"key":"R4-20240828","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.ajhg.2016.08.019","article-title":"Periodontal Ehlers-Danlos syndrome is caused by mutations in C1R and C1S, which encode subcomponents C1r and C1s of complement","volume":"99","author":"Kapferer-Seebacher","year":"2016","journal-title":"Am J Hum Genet"},{"key":"R5-20240828","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1111\/hae.13800","article-title":"An update on the new classification of Ehlers-Danlos syndrome and review of the causes of bleeding in this population","volume":"25","author":"Jesudas","year":"2019","journal-title":"Haemophilia"},{"key":"R6-20240828","doi-asserted-by":"crossref","first-page":"1088","DOI":"10.1111\/jcpe.12807","article-title":"Periodontal manifestations of Ehlers-Danlos syndromes: A systematic review","volume":"44","author":"Kapferer-Seebacher","year":"2017","journal-title":"J Clin Periodontol"},{"issue":"Suppl 20","key":"R7-20240828","first-page":"S219","article-title":"Periodontal manifestations of systemic diseases and developmental and acquired conditions: Consensus report of workgroup 3 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45","author":"Jepsen","year":"2018","journal-title":"J Clin Periodontol"},{"key":"R8-20240828","doi-asserted-by":"crossref","first-page":"152","DOI":"10.1111\/prd.12201","article-title":"Nonsurgical and surgical treatment of periodontitis: How many options for one 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A case report and literature review","volume":"73","author":"Perez","year":"2002","journal-title":"J Periodontol"},{"key":"R10-20240828","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/ajmg.c.31552","article-title":"The 2017 international classification of the Ehlers-Danlos syndromes","volume":"175","author":"Malfait","year":"2017","journal-title":"Am J Med Genet C Semin Med Genet"}],"container-title":["Journal of Indian Society of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jisp.jisp_266_22","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:48:58Z","timestamp":1787770138000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jisp.jisp_266_22"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023]]}},"URL":"https:\/\/doi.org\/10.4103\/jisp.jisp_266_22","relation":{},"ISSN":["0972-124X","0975-1580"],"issn-type":[{"value":"0972-124X","type":"print"},{"value":"0975-1580","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,1]]},"assertion":[{"value":"2022-05-26","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-18","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}