{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:54:04Z","timestamp":1793332444888,"version":"4.5.0"},"reference-count":16,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The prevalence of inherited bleeding disorders (BDs) is low in the general population (10\u201320 per 100,000 individuals), particularly hemophilia B cases, which may remain undiagnosed for a very long time until exposed to some surgical procedure. The dental professional must be aware of the possibility that patients with no previous history of abnormal bleeding may manifest their first bleeding episode in the dental office. Particularly as periodontists, we often encounter patients with bleeding gums and severe bleeding complications may precipitate while performing routine periodontal procedures. Hence, we must have a thorough knowledge of BDs and their management in challenging hemorrhagic situations. Management of such patients necessitates a multidisciplinary approach by involving the patient\u2019s hematologist and advanced laboratory facilities. The present case report is an attempt to discuss the diagnosis and management of a bleeding episode that occurred post periodontal flap surgery in an undiagnosed hemophilia B patient.<\/jats:p>","DOI":"10.4103\/jisp.jisp_308_23","type":"journal-article","created":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T17:10:57Z","timestamp":1725124257000},"page":"258-261","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Spontaneous postoperative bleeding after periodontal procedure: An alarming sign of bleeding disorder"],"prefix":"10.4103","volume":"28","author":[{"given":"Shivani","family":"Mishra","sequence":"first","affiliation":[{"name":"Department of Periodontology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhu Singh","family":"Ratre","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Parul","family":"Jain","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,8,31]]},"reference":[{"key":"R1-20240831","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1111\/j.1600-0757.2006.00203.x","article-title":"Bleeding disorders and periodontology","volume":"44","author":"Vassilopoulos","year":"2007","journal-title":"Periodontol 2000"},{"key":"R2-20240831","first-page":"19","article-title":"Epidemiology and social costs of haemophilia in India","volume":"140","author":"Kar","year":"2014","journal-title":"Indian J Med Res"},{"key":"R3-20240831","first-page":"827","article-title":"Bleeding disorders: Characterization, dental considerations and management","volume":"72","author":"Israels","year":"2006","journal-title":"J Can Dent Assoc"},{"key":"R4-20240831","doi-asserted-by":"crossref","first-page":"1935","DOI":"10.1111\/jth.12672","article-title":"Definitions in hemophilia: Communication from the SSC of the ISTH","volume":"12","author":"Blanchette","year":"2014","journal-title":"J Thromb Haemost"},{"key":"R5-20240831","first-page":"628","article-title":"Treatment of gingival enlargement","year":"2019","journal-title":"Newman and Carranza's Clinical Periodontology"},{"key":"R6-20240831","doi-asserted-by":"crossref","first-page":"281","DOI":"10.4103\/jisp.jisp_461_18","article-title":"Dental management of a patient with incidentally detected hemophilia: Report of a clinical case","volume":"23","author":"Nagarakanti","year":"2019","journal-title":"J Indian Soc Periodontol"},{"key":"R7-20240831","article-title":"Dental management of a child with incidentally detected hemophilia: Report of a clinical case","author":"Mart\u00ednez-Rider","year":"2017","journal-title":"Case Rep Dent 2017"},{"key":"R8-20240831","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1186\/s12903-022-02074-9","article-title":"Uncontrollable bleeding after tooth extraction from asymptomatic mild hemophilia patients: Two case reports","volume":"22","author":"Fan","year":"2022","journal-title":"BMC Oral Health"},{"key":"R9-20240831","doi-asserted-by":"crossref","first-page":"779","DOI":"10.12998\/wjcc.v3.i9.779","article-title":"Gingival enlargements: Differential diagnosis and review of literature","volume":"3","author":"Agrawal","year":"2015","journal-title":"World J Clin Cases"},{"key":"R10-20240831","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1038\/sj.bdj.4810526","article-title":"General medicine and surgery for dental practitioners part 9: Haematology and patients with bleeding problems","volume":"195","author":"Meechan","year":"2003","journal-title":"Br Dent J"},{"key":"R11-20240831","doi-asserted-by":"crossref","first-page":"445","DOI":"10.2147\/TACG.S288256","article-title":"The clinical genetics of hemophilia B (factor IX deficiency)","volume":"14","author":"Miller","year":"2021","journal-title":"Appl Clin Genet"},{"key":"R12-20240831","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/adj.12813","article-title":"Inherited bleeding disorders in oral procedures. Assessment of prophylactic and therapeutic protocols: A scoping review","volume":"66","author":"de Azevedo Kinalski","year":"2021","journal-title":"Aust Dent J"},{"key":"R13-20240831","first-page":"454","article-title":"Bleeding and clotting disorders","author":"Patton","year":"2003","journal-title":"Burket's Oral Medicine: Diagnosis and Treatment"},{"key":"R14-20240831","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1080\/17474086.2023.2293092","article-title":"National strategic advocacy to manage patients with inherited bleeding disorders in low and lower-middle income countries","volume":"16","author":"Chuansumrit","year":"2023","journal-title":"Expert Rev Hematol"},{"key":"R15-20240831","first-page":"77","article-title":"Bleeding disorders of importance in dental care and related patient management","volume":"73","author":"Gupta","year":"2007","journal-title":"J Can Dent Assoc"},{"issue":"Suppl 6","key":"R16-20240831","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/hae.14046","article-title":"WFH guidelines for the management of hemophilia, 3rd edition","volume":"26","author":"Srivastava","year":"2020","journal-title":"Haemophilia"}],"container-title":["Journal of Indian Society of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jisp.jisp_308_23","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:17:28Z","timestamp":1787771848000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jisp.jisp_308_23"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":16,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jisp.jisp_308_23","relation":{},"ISSN":["0972-124X","0975-1580"],"issn-type":[{"value":"0972-124X","type":"print"},{"value":"0975-1580","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"assertion":[{"value":"2023-06-14","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-07-10","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}