{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T16:43:49Z","timestamp":1787071429530,"version":"build-2736575974"},"reference-count":14,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"5","license":[{"start":{"date-parts":[[2025,9,1]],"date-time":"2025-09-01T00:00:00Z","timestamp":1756684800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2025,9]]},"abstract":"<jats:title>Abstract:<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Maxillary sinus augmentation is a predictable procedure to increase bone height in atrophic posterior maxilla. Different protocols and procedures for sinus lift are available. Many biomaterials are employed in this technique; however, no biomaterial has been proven as the best.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>A single-center, prospective, interventional, single-arm study was done for evaluation of the efficacy of biphasic calcium phosphate mixed in a 1:1 ratio with autogenous bone graft. Patients with \u22645 mm of subantral bone height were recruited. Sinus membrane was elevated using piezosurgical tips and sinus elevators, and a graft was placed to achieve the desired bone height. Lateral window was covered by platelet-rich fibrin membrane, and suturing was done. After 6 months, bone biopsy specimens were harvested, and histomorphometric analysis was performed. Subantral bone height was measured on cone-beam computed tomography at baseline and at 6 months to get the bone height gain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>(1) The mean gain of bone height was 8.53 \u00b1 1.07 which was statistically significant. (2) On histologic evaluation, new bone% was 48.08% \u00b1 2.41%, soft tissue% was 27.25% \u00b1 3.18%, and residual graft% was 24.36% \u00b1 2.91%. (3) The density and distribution of cells were favorable. (4) All patients had pain and swelling in mild range. (5) No major intra- or postoperative complications were noted.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The described surgical technique using a combination of hydroxyapatite + beta-tricalcium phosphate 30\/70 along with autogenous bone in a 1:1 ratio offers a predictable and practical treatment choice in direct sinus augmentation. It provided significant bone height gain, new bone formation, and good implant stability in grafted sites.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jisp.jisp_30_25","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T08:01:38Z","timestamp":1765958498000},"page":"529-536","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of the efficacy of autogenous bone graft in combination with hydroxyapatite and beta-tricalcium phosphate in direct sinus augmentation \u2013 A clinical, radiographic, and histologic study"],"prefix":"10.4103","volume":"29","author":[{"given":"Jaya","family":"Nathani","sequence":"first","affiliation":[{"name":"Department of Periodontology, Bhabha College of Dental Sciences, Bhopal, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaleen","family":"Khetarpal","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madhu Singh","family":"Ratre","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Satyajit Ashok","family":"Tekade","sequence":"additional","affiliation":[{"name":"Department of Oral and Maxillofacial Pathology, Modern Dental College and Research Center, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Verma","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government College of Dentistry, Indore, Madhya Pradesh, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,12,17]]},"reference":[{"key":"R1-20251220","doi-asserted-by":"crossref","first-page":"285","DOI":"10.5051\/jpis.2007220361","article-title":"Factors affecting maxillary sinus pneumatization following posterior maxillary tooth extraction","volume":"51","author":"Lim","year":"2021","journal-title":"J Periodontal Implant Sci"},{"key":"R4-20251220","doi-asserted-by":"crossref","first-page":"464","DOI":"10.1563\/aaid-joi-D-21-00310","article-title":"Bone graft osseous changes after maxillary sinus floor augmentation:A systematic review","volume":"48","author":"Al-Moraissi","year":"2022","journal-title":"J Oral Implantol"},{"key":"R5-20251220","first-page":"55","article-title":"An opportunity in peri-implantology:PRF","volume":"42","author":"Choukroun","year":"2001","journal-title":"Implant dentistry"},{"key":"R6-20251220","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1097\/ID.0b013e3181faa8af","article-title":"Simultaneous sinus-lift and implantation using microthreaded implants and leukocyte- and platelet-rich fibrin as sole grafting material:A six-year experience","volume":"20","author":"Simonpieri","year":"2011","journal-title":"Implant Dent"},{"key":"R7-20251220","first-page":"432","article-title":"Maxillary sinus floor augmentation using a beta-tricalcium phosphate (Cerasorb) alone compared to autogenous bone grafts","volume":"20","author":"Zijderveld","year":"2005","journal-title":"Int J Oral Maxillofac Implants"},{"key":"R8-20251220","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1002\/jbm.b.30199","article-title":"HA\/TCP compounding of a porous CaP biomaterial improves bone formation and scaffold degradation \u2013A long-term histological study","volume":"74","author":"Schopper","year":"2005","journal-title":"J Biomed Mater Res B Appl Biomater"},{"key":"R9-20251220","doi-asserted-by":"crossref","first-page":"65","DOI":"10.11607\/jomi.3709","article-title":"Effect of different hydroxyapatite:\u03b2-tricalcium phosphate ratios on the osteoconductivity of biphasic calcium phosphate in the rabbit sinus model","volume":"30","author":"Lim","year":"2015","journal-title":"Int J Oral Maxillofac Implants"},{"key":"R10-20251220","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1902\/annals.2003.8.1.328","article-title":"Effect of maxillary sinus augmentation on the survival of endosseous dental implants. A systematic review","volume":"8","author":"Wallace","year":"2003","journal-title":"Ann Periodontol"},{"key":"R11-20251220","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1111\/j.1600-051X.2008.01272.x","article-title":"A systematic review of the success of sinus floor elevation and survival of implants inserted in combination with sinus floor elevation:Part I:Lateral approach","volume":"35","author":"Pjetursson","year":"2008","journal-title":"J Clin Periodontol"},{"key":"R12-20251220","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1111\/j.1600-0501.2009.01821.x","article-title":"The use of straumann bone ceramic in a maxillary sinus floor elevation procedure:A clinical, radiological, histological and histomorphometric evaluation with a 6-month healing period","volume":"21","author":"Frenken","year":"2010","journal-title":"Clin Oral Implants Res"},{"key":"R13-20251220","doi-asserted-by":"crossref","first-page":"462","DOI":"10.3390\/coatings10050462","article-title":"The use of autogenous bone mixed with a biphasic calcium phosphate in a maxillary sinus floor elevation procedure with a 6-month healing time:A clinical, radiological, histological and histomorphometric evaluation","volume":"10","author":"Bouwman","year":"2020","journal-title":"Coatings"},{"key":"R14-20251220","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.11607\/jomi.8211","article-title":"Sinus floor elevation with biphasic calcium phosphate or deproteinized bovine bone mineral:Clinical and histomorphometric outcomes of a randomized controlled clinical trial","volume":"35","author":"Kraus","year":"2020","journal-title":"Int J Oral Maxillofac Implants"},{"key":"R15-20251220","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1111\/j.1600-0501.2007.01498.x","article-title":"Osteotomy and membrane elevation during the maxillary sinus augmentation procedure. A comparative study:Piezoelectric device versus conventional rotative instruments","volume":"19","author":"Barone","year":"2008","journal-title":"Clin Oral Implants Res"},{"key":"R16-20251220","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1097\/ID.0000000000000001","article-title":"Comparison of piezosurgery and conventional rotative instruments in direct sinus lifting","volume":"22","author":"Delilbasi","year":"2013","journal-title":"Implant Dent"}],"container-title":["Journal of Indian Society of Periodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jisp.jisp_30_25","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T15:46:03Z","timestamp":1787067963000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jisp.jisp_30_25"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2025]]}},"URL":"https:\/\/doi.org\/10.4103\/jisp.jisp_30_25","relation":{},"ISSN":["0972-124X","0975-1580"],"issn-type":[{"value":"0972-124X","type":"print"},{"value":"0975-1580","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9]]},"assertion":[{"value":"2025-01-21","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-01","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}