{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T14:42:01Z","timestamp":1786718521916,"version":"build-2736575974"},"reference-count":40,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Indian Soc Periodontol"],"published-print":{"date-parts":[[2018]]},"DOI":"10.4103\/jisp.jisp_320_17","type":"journal-article","created":{"date-parts":[[2018,4,23]],"date-time":"2018-04-23T03:23:11Z","timestamp":1524453791000},"page":"133","source":"Crossref","is-referenced-by-count":11,"title":["Application of bioelectric effect to reduce the antibiotic resistance of subgingival plaque biofilm: An in vitro study"],"prefix":"10.4103","volume":"22","author":[{"given":"Padmini","family":"Hari","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KranthiRaja","family":"Kacharaju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naveen","family":"Anumala","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"KrishnanjaneyaReddy","family":"Pathakota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayakumar","family":"Avula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"key-10.4103\/0972-124X.230836-1","first-page":"7","volume-title":"Dental plaque: Biological significance of a biofilm and community life-style","author":"Marsh","year":"2005","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.230836-2","first-page":"5002","volume-title":"The human oral microbiome","author":"Dewhirst","year":"2010","journal-title":"J Bacteriol"},{"key":"key-10.4103\/0972-124X.230836-3","first-page":"16","volume-title":"Plaque as a biofilm: Pharmacological principles of drug delivery and action in the sub-and supragingival environment","author":"Marsh","year":"2003","journal-title":"Oral Dis"},{"key":"key-10.4103\/0972-124X.230836-4","first-page":"362","volume-title":"Periodontitis as a biofilm infection","author":"Chen","year":"2001","journal-title":"J Calif Dent Assoc"},{"key":"key-10.4103\/0972-124X.230836-5","first-page":"160","volume-title":"Antibiotic resistance in human chronic periodontitis microbiota","author":"Rams","year":"2014","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.230836-6","first-page":"204","volume-title":"The challenge of treating biofilm-associated bacterial infections","author":"del","year":"2007","journal-title":"Clin Pharmacol Ther"},{"key":"key-10.4103\/0972-124X.230836-7","first-page":"79","volume-title":"Susceptibility of oral bacterial biofilms to antimicrobial agents","author":"Wilson","year":"1996","journal-title":"J Med Microbiol"},{"key":"key-10.4103\/0972-124X.230836-8","first-page":"45","volume-title":"Systemic antibiotic therapy in periodontics","author":"van","year":"2000","journal-title":"Periodontol"},{"key":"key-10.4103\/0972-124X.230836-9","first-page":"545","volume-title":"Antibiotics in the treatment of human periodontal diseases","author":"Genco","year":"1981","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.230836-10","first-page":"12","volume-title":"Dental biofilms: Difficult therapeutic targets","author":"Socransky","year":"2000","journal-title":"Periodontol"},{"key":"key-10.4103\/0972-124X.230836-11","first-page":"1318","volume-title":"Bacterial biofilms: A common cause of persistent infections","author":"Costerton","year":"1999","journal-title":"Science"},{"key":"key-10.4103\/0972-124X.230836-12","first-page":"187","volume-title":"Biofilms as complex differentiated communities","author":"Stoodley","year":"2002","journal-title":"Annu Rev Microbiol"},{"key":"key-10.4103\/0972-124X.230836-13","first-page":"2043","volume-title":"Testing the susceptibility of bacteria in biofilms to antibacterial agents","author":"Anwar","year":"1990","journal-title":"Antimicrob Agents Chemother"},{"key":"key-10.4103\/0972-124X.230836-14","first-page":"751","volume-title":"The antibacterial effect of photodynamic therapy in dental plaque-derived biofilms","author":"Fontana","year":"2009","journal-title":"J Periodontal Res"},{"key":"key-10.4103\/0972-124X.230836-15","first-page":"283","volume-title":"Ultrasonic enhancement of antibiotic action on several species of bacteria","author":"Rediske","year":"1999","journal-title":"J Gen Appl Microbiol"},{"key":"key-10.4103\/0972-124X.230836-16","first-page":"3770","volume-title":"Electrical enhancement of biocide efficacy against Pseudomonas aeruginosa biofilms","author":"Blenkinsopp","year":"1992","journal-title":"Appl Environ Microbiol"},{"key":"key-10.4103\/0972-124X.230836-17","first-page":"2803","volume-title":"Mechanism of electrical enhancement of efficacy of antibiotics in killing biofilm bacteria","author":"Costerton","year":"1994","journal-title":"Antimicrob Agents Chemother"},{"key":"key-10.4103\/0972-124X.230836-18","first-page":"6871","volume-title":"Electric current-induced detachment of Staphylococcus epidermidis biofilms from surgical stainless steel","author":"van","year":"2004","journal-title":"Appl Environ Microbiol"},{"key":"key-10.4103\/0972-124X.230836-19","first-page":"333","volume-title":"Antibiotic resistance in anin vitro subgingival biofilm model","author":"Sedlacek","year":"2007","journal-title":"Oral Microbiol Immunol"},{"key":"key-10.4103\/0972-124X.230836-20","first-page":"15016","volume-title":"Effect of electrical energy on the efficacy of biofilm treatment using the bioelectric effect","author":"Kim","year":"2015","journal-title":"NPJ Biofilms Microbiomes"},{"key":"key-10.4103\/0972-124X.230836-21","unstructured":"Dalziel CF. Deleterious Effects of Electric Shock. Meeting of Experts on Electrical Accidents and Related Matters. Geneva; 1961. p. 23-31. Available from: http:\/\/www.electriciancalculators.com\/dalziel\/dalziel_study.pdf. [Last accessed on 2017 Sep 24]."},{"key":"key-10.4103\/0972-124X.230836-22","first-page":"152","volume-title":"Anin vitro biofilm model of subgingival plaque","author":"Walker","year":"2007","journal-title":"Oral Microbiol Immunol"},{"key":"key-10.4103\/0972-124X.230836-23","first-page":"511","volume-title":"Electrical enhancement of chlorhexidine efficacy against periodontal pathogen porphyromonas gingivalis within a biofilm","author":"Lasserre","year":"2015","journal-title":"New Microbiol"},{"key":"key-10.4103\/0972-124X.230836-24","first-page":"110","volume-title":"Artificial dental plaque biofilm model systems","author":"Sissons","year":"1997","journal-title":"Adv Dent Res"},{"key":"key-10.4103\/0972-124X.230836-25","first-page":"450","volume-title":"Continuous culture of mixed oral flora on hydroxyapatite-coated glass beads","author":"Sudo","year":"1977","journal-title":"Appl Environ Microbiol"},{"key":"key-10.4103\/0972-124X.230836-26","first-page":"261","volume-title":"An apparatus for the continuous culture of micro-organisms on solid surfaces with special reference to dental plaque","author":"Dibdin","year":"1976","journal-title":"J Appl Bacteriol"},{"key":"key-10.4103\/0972-124X.230836-27","first-page":"4662","volume-title":"Aradio frequency electric current enhances antibiotic efficacy against bacterial biofilms","author":"Caubet","year":"2004","journal-title":"Antimicrob Agents Chemother"},{"key":"key-10.4103\/0972-124X.230836-28","first-page":"165","volume-title":"Inhibition of SA-1 tumor growth in mice by human leukocyte interferon alpha combined with low-level direct current","author":"Sersa","year":"1990","journal-title":"Mol Biother"},{"key":"key-10.4103\/0972-124X.230836-29","first-page":"e34","volume-title":"Electrical stimulation in bone healing: Critical analysis by evaluating levels of evidence","author":"Griffin","year":"2011","journal-title":"Eplasty"},{"key":"key-10.4103\/0972-124X.230836-30","first-page":"177","volume-title":"Electric shock and human body","author":"Prasad","year":"2010","journal-title":"Int J Elec Power Eng"},{"key":"key-10.4103\/0972-124X.230836-31","first-page":"1285","volume-title":"Pharmacokinetic profile of a locally administered doxycycline gel in crevicular fluid, blood, and saliva","author":"Kim","year":"2002","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.230836-32","first-page":"1085","volume-title":"The pharmacokinetic profile of a biodegradable controlled-release delivery system containing doxycycline compared to systemically delivered doxycycline in gingival crevicular fluid, saliva, and serum","author":"Stoller","year":"1998","journal-title":"J Periodontol"},{"key":"key-10.4103\/0972-124X.230836-33","first-page":"286","volume-title":"Comparison of the pharmacokinetic profiles of two locally administered doxycycline gels in crevicular fluid and saliva","author":"Kim","year":"2004","journal-title":"J Clin Periodontol"},{"key":"key-10.4103\/0972-124X.230836-34","first-page":"25","volume-title":"A comparative evaluation of the clinical effects of systemic and local doxycycline in the treatment of chronic periodontitis","author":"Akalin","year":"2004","journal-title":"J Oral Sci"},{"key":"key-10.4103\/0972-124X.230836-35","first-page":"6364","volume-title":"Removal and inactivation of Staphylococcus epidermidis biofilms by electrolysis","author":"Rabinovitch","year":"2006","journal-title":"Appl Environ Microbiol"},{"key":"key-10.4103\/0972-124X.230836-36","first-page":"6379","volume-title":"Assessment of the ability of the bioelectric effect to eliminate mixed-species biofilms","author":"Shirtliff","year":"2005","journal-title":"Appl Environ Microbiol"},{"key":"key-10.4103\/0972-124X.230836-37","first-page":"41","volume-title":"The electricidal effect: Reduction of Staphylococcus and Pseudomonas biofilms by prolonged exposure to low-intensity electrical current","author":"del","year":"2009","journal-title":"Antimicrob Agents Chemother"},{"key":"key-10.4103\/0972-124X.230836-38","first-page":"292","volume-title":"Electrolytic generation of oxygen partially explains electrical enhancement of tobramycin efficacy against Pseudomonas aeruginosa biofilm","author":"Stewart","year":"1999","journal-title":"Antimicrob Agents Chemother"},{"key":"key-10.4103\/0972-124X.230836-39","first-page":"1876","volume-title":"Influence of electric fields and pH on biofilm structure as related to the bioelectric effect","author":"Stoodley","year":"1997","journal-title":"Antimicrob Agents Chemother"},{"key":"key-10.4103\/0972-124X.230836-40","first-page":"786","volume-title":"Bioelectric effect and bacterial biofilms.A systematic review","author":"Del","year":"2008","journal-title":"Int J Artif Organs"}],"container-title":["Journal of Indian Society of Periodontology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T13:36:02Z","timestamp":1786714562000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jisp.jisp_320_17"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018]]},"references-count":40,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2018]]}},"alternative-id":["230836"],"URL":"https:\/\/doi.org\/10.4103\/jisp.jisp_320_17","relation":{},"ISSN":["0972-124X"],"issn-type":[{"value":"0972-124X","type":"print"}],"subject":[],"published":{"date-parts":[[2018]]}}}