{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:30:08Z","timestamp":1786728608188,"version":"build-2736575974"},"reference-count":25,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract:<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Nonsurgical periodontal treatment improves clinical parameters; however, the procedure is often associated with patient discomfort. Pain control should be considered during periodontal instrumentation. This study evaluated pain perception during periodontal instrumentation using computerized anesthesia versus a noninvasive lidocaine\/prilocaine gel.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      A parallel, blinded, randomized, clinical trial included 76 volunteers receiving either invasive anesthesia with a computerized device, or noninvasive anesthesia with lidocaine\/prilocaine gel during nonsurgical periodontal instrumentation. Pain perception was assessed using an 11-point Numerical Rating Scale and anxiety with the Modified Dental Anxiety Scale. Anesthetic supplementation needs were recorded, and hemodynamic parameters were measured before and after anesthesia. Statistical analyses used the\n                      <jats:italic toggle=\"yes\">t<\/jats:italic>\n                      -test or Mann\u2013Whitney test for quantitative variables. Qualitative variables were analyzed using the Chi-square test (\u03b1 = 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Participants included 45 women and 31 men (mean age of 44.2 \u00b1 12.9 years), with no significant differences in age or sex between groups. Pain intensity was similar between groups. Anxiety was similar among participants, most having low anxiety (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05). The need for supplementary anesthesia differed significantly between groups. All patients (38; 100%) in the noninvasive group required additional anesthesia. In the invasive group, only nine patients (24%) required additional anesthesia (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.001). Systolic and diastolic blood pressure, along with oxygen saturation, remained stable, with no relevant variations among the study groups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Both techniques provided similar pain control during periodontal instrumentation; however, the noninvasive gel required significantly more supplementary anesthesia in comparison with the computerized-controlled system. Pretreatment anxiety levels were low and comparable between groups.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jisp.jisp_321_25","type":"journal-article","created":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:01:21Z","timestamp":1778684481000},"page":"94-99","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["Comparative efficacy of different anesthetic techniques on pain perception during nonsurgical periodontal treatment: A parallel, blinded, randomized controlled trial"],"prefix":"10.4103","volume":"30","author":[{"given":"Gabriel Andreani","family":"Cabral","sequence":"first","affiliation":[{"name":"Department of Dentistry, Ponta Grossa State University \u2013 UEPG, Ponta Grossa, Paran\u00e1, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Huller","sequence":"additional","affiliation":[{"name":"Department of Dentistry, Ponta Grossa State 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