{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:32:22Z","timestamp":1787772742031,"version":"build-2784847793"},"reference-count":39,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Marginal tissue recession is a frequent clinical scenario that creates substantial compromise in esthetic appearance of the patient. The current randomized, double-blind interventional trial aims to evaluate the effectiveness of the combination of \u201cplatelet rich fibrin (PRF)\u201d membrane with bioresorbable guided tissue regeneration (GTR) membrane as compared to GTR membrane alone utilizing \u201cdouble lateral sliding bridge flap (DLSBF) technique\u201d for the management of simultaneous GR defects in human subjects.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Twenty subjects were randomly allotted in two groups: Group 1 (test): 10 subjects treated with PRF + GTR membrane using DLSBF technique and Group 2 (control): 10 subjects treated with GTR membrane alone using DLSBF technique. Clinical measurements such as relative gingival marginal level, \u201crelative clinical attachment level (R-CAL),\u201d \u201cprobing pocket depth (PPD),\u201d \u201cgingival recession (GR),\u201d and \u201cwidth of keratinized gingiva (WKG) and gingival thickness (GT)\u201d were evaluated at the initiation of the study and 6 months thereafter.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Two groups showed statistically significant differences with respect to probing depth reduction, CAL gain, and increase in WKG and GT. No significant result was observed with mean root coverage (RC) and complete RC for test (84.80% \u00b1 19.53% and 54.99% \u00b1 38.53%) and control group (75.69% \u00b1 18.86% and 35.83% \u00b1 39.29%), respectively.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The combination of PRF membrane used along with GTR membrane provides no additional benefits over GTR membrane alone. However, the DLSBF technique convincingly shows simultaneous elimination of multiple problems associated with GR, shallow vestibule, hypersensitivity, and aberrant frenum pull in a single stage with meticulous performance.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jisp.jisp_322_21","type":"journal-article","created":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T23:10:37Z","timestamp":1651446637000},"page":"245-253","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":5,"title":["Platelet rich fibrin in combination with bioabsorbable guided tissue regeneration (GTR) membrane and GTR membrane alone using double lateral sliding bridge flap for treatment of multiple gingival recession defects in humans"],"prefix":"10.4103","volume":"26","author":[{"given":"Kiran Rajesh","family":"Sethiya","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prasad","family":"Dhadse","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pavan","family":"Bajaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khushboo","family":"Durge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitrika","family":"Subhadarsanee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safiya","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-10-20240828","doi-asserted-by":"crossref","first-page":"411","DOI":"10.4103\/0972-124X.100921","article-title":"A comparative clinical evaluation of acellular dermal matrix allograft and sub-epithelial connective tissue graft for the treatment of multiple gingival recessions","volume":"16","author":"Koudale","year":"2012","journal-title":"J Indian Soc Periodontol"},{"key":"R2-10-20240828","first-page":"653","article-title":"Minimally invasive treatment of maxillary anterior gingival recession defects by vestibular incision subperiosteal tunnel access and platelet derived growth factor BB","volume":"31","author":"Zadeh","year":"2011","journal-title":"Int J Periodontics Restorative Dent"},{"key":"R3-10-20240828","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1111\/j.1600-051X.2009.01492.x","article-title":"Treatment of class III multiple gingival recessions: A randomized-clinical trial","volume":"37","author":"Aroca","year":"2010","journal-title":"J Clin Periodontol"},{"key":"R4-10-20240828","first-page":"395","article-title":"Tunneling procedure for root coverage using acellular dermal matrix: A case series","volume":"29","author":"Modaressi","year":"2009","journal-title":"Int J Periodontics Restorative Dent"},{"key":"R5-10-20240828","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1902\/jop.2009.080253","article-title":"Clinical evaluation of a modified coronally advanced flap alone or in combination with a platelet-rich fibrin membrane for the treatment of adjacent multiple gingival recessions: A 6-month study","volume":"80","author":"Aroca","year":"2009","journal-title":"J Periodontol"},{"key":"R6-10-20240828","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1902\/annals.2003.8.1.303","article-title":"Surgical therapies for the treatment of gingival recession. 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