{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T17:30:04Z","timestamp":1786728604930,"version":"build-2736575974"},"reference-count":26,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:title>Abstract:<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>This study investigates the association between obesity and the prevalence of periodontopathic bacteria in obese\/overweight individuals and healthy\/normal-weight individuals, focusing mainly on the red complex organisms in individuals with and without periodontitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      A cross-sectional study was conducted with 14 participants (7 obese\/overweight and 7 healthy weight individuals), further categorized into periodontitis and healthy periodontium groups. Body mass index and waist-to-hip ratio were measured, total cholesterol level was determined, and probing pocket depth was determined. Subgingival plaque samples were obtained and examined for the presence of\n                      <jats:italic toggle=\"yes\">Tannerella forsythia<\/jats:italic>\n                      ,\n                      <jats:italic toggle=\"yes\">Porphyromonas gingivalis<\/jats:italic>\n                      , and\n                      <jats:italic toggle=\"yes\">Treponema denticola<\/jats:italic>\n                      through the quantitative real-time polymerase chain reaction analysis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Obese patients had a significant association with\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      .\n                      <jats:italic toggle=\"yes\">gingivalis<\/jats:italic>\n                      . In contrast,\n                      <jats:italic toggle=\"yes\">T<\/jats:italic>\n                      .\n                      <jats:italic toggle=\"yes\">forsythia<\/jats:italic>\n                      and\n                      <jats:italic toggle=\"yes\">T<\/jats:italic>\n                      .\n                      <jats:italic toggle=\"yes\">denticola<\/jats:italic>\n                      numbers were not statistically significant. Five out of seven obese participants had periodontitis, compared to four out of seven participants in the healthy weight group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Within the limitations of this pilot cross-sectional study, obesity was associated with an increased prevalence of\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      .\n                      <jats:italic toggle=\"yes\">gingivalis<\/jats:italic>\n                      in individuals with periodontitis. These findings suggest that obesity may have a possible association with alterations in the subgingival red complex bacterial profile. However, results should be interpreted cautiously, and larger longitudinal studies are required to confirm these observations.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jisp.jisp_35_25","type":"journal-article","created":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T15:00:56Z","timestamp":1778684456000},"page":"135-140","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of the relationship between subgingival microbiome in obese and nonobese clinically healthy and periodontitis patients \u2013 An experimental study"],"prefix":"10.4103","volume":"30","author":[{"given":"Supraja","family":"Govindarajan","sequence":"first","affiliation":[{"name":"Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai, Tamil Nadu, 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