{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:53:57Z","timestamp":1793332437150,"version":"4.5.0"},"reference-count":21,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Surgical site infection (SSI) is one of the common postoperative complications observed after various periodontal surgeries, and sutures play a vital role in its causation. Thus, the aim of this study is to evaluate and compare the efficacy of a novel tetracycline-coated suture with triclosan-coated and nonantibacterial-coated sutures on bacterial load reduction to prevent SSI by measuring the zone of inhibition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>Twenty systemically healthy individuals with moderate chronic periodontitis were included in this study. Fresh unstimulated saliva was collected from each patient and inoculated on three different blood agar plates. Sutures were divided into three groups (Group A: Tetracycline-coated suture, Group B: Triclosan-coated suture, Group C [control group]: Nonantibacterial-coated suture). The antibacterial efficacy of each suture was evaluated by performing agar diffusion test. The zone of inhibition around each suture was calculated, and statistical analysis was performed for the same using Kruskall\u2013Wallis ANOVA test and Mann\u2013Whitney U-test.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      On intergroup comparison, there was a statistically highly significant difference seen for the zone of inhibition between the groups (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01) with the highest values in Group A (14.45 mm), followed by Group B (1.4 mm) and least in Group C (0 mm).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>\n                      Tetracycline-coated suture is more efficacious than triclosan-coated suture to reduce bacterial load and further prevent SSIs. However,\n                      <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                      clinical trial is must to prove the same.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jisp.jisp_453_21","type":"journal-article","created":{"date-parts":[[2022,12,5]],"date-time":"2022-12-05T09:25:50Z","timestamp":1670232350000},"page":"539-543","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":2,"title":["Comparative evaluation of the efficacy of a novel tetracycline-coated suture with triclosan-coated and noncoated sutures on bacterial load reduction: A prospective in vitro study"],"prefix":"10.4103","volume":"26","author":[{"given":"Akshaya Bhupesh","family":"Banodkar","sequence":"first","affiliation":[{"name":"Department of Periodontology, Government Dental College and Hospital, St. George Hospital Campus, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vaibhavi Pandurang","family":"Nandgaonkar","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government Dental College and Hospital, St. George Hospital Campus, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh Prabhakar","family":"Gaikwad","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government Dental College and Hospital, St. George Hospital Campus, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynette Custodio","family":"Fernandes","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government Dental College and Hospital, St. George Hospital Campus, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chitra Laxmikant","family":"Patil","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government Dental College and Hospital, St. George Hospital Campus, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amrita Dharmendra","family":"Batho","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Government Dental College and Hospital, St. George Hospital Campus, Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2022,11,14]]},"reference":[{"key":"B1-20240828","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1089\/sur.2010.9932","article-title":"Perspectives in surgical infections:What does the future hold?","volume":"11","author":"Napolitano","year":"2010","journal-title":"Surg Infect (Larchmt)"},{"key":"B2-20240828","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1097\/00000658-198107000-00007","article-title":"Bacterial adherence to surgical sutures. 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