{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T18:23:08Z","timestamp":1787768588810,"version":"build-2784847793"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"6","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Hereditary gingival fibromatosis (HGF) is an uncommon slow-growing fibrous overgrowth characterized by connective tissue accumulation. It presents as an isolated feature or as a manifestation of any syndrome. Various syndromes associated with HGF are inherited by autosomal dominant\/recessive\/X-linked traits. Zimmermann\u2013Laband syndrome (ZLS) is a rare, autosomal dominant inherited disease manifested with gingival fibromatosis (GF), nose and ears abnormalities, and hypoplastic\/dysplastic nails or terminal phalanges of hand and feet. Although the pattern of inheritance was found to be both autosomal dominant and recessive traits, the molecular basis is still unclear. This report presents a possible case of ZLS-associated HGF in a 25-year-old female patient who presents with GF, hypertrichosis, and other syndrome-related features. Her father was similarly affected whereas her mother and sibling were asymptomatic. The patient and her family members were explained about the condition and surgical periodontal therapy was carried out for the patient to improve esthetics and was followed up regularly. Esthetics was significantly improved and no recurrence was noted at the end of 6 months.<\/jats:p>","DOI":"10.4103\/jisp.jisp_582_22","type":"journal-article","created":{"date-parts":[[2024,1,25]],"date-time":"2024-01-25T16:00:55Z","timestamp":1706198455000},"page":"645-650","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":1,"title":["Zimmermann\u2013Laband syndrome-associated hereditary gingival fibromatosis"],"prefix":"10.4103","volume":"27","author":[{"given":"Jaishree Tukaram","family":"Kshirsagar","sequence":"first","affiliation":[{"name":"Department of Periodontology, Tamil Nadu Government Dental College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kalaiselvan","family":"Dharani","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Tamil Nadu Government Dental College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyangha","family":"Thangavel","sequence":"additional","affiliation":[{"name":"Department of Periodontology, Tamil Nadu Government Dental College and Hospital, Chennai, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2024,1,24]]},"reference":[{"key":"R1-20240828","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1902\/jop.2006.050379","article-title":"Hereditary gingival fibromatosis:A systematic review","volume":"77","author":"Coletta","year":"2006","journal-title":"J Periodontol"},{"issue":"Suppl 1","key":"R2-20240828","first-page":"S1","article-title":"A new classification scheme for periodontal and peri-implant diseases and conditions \u2013Introduction and key changes from the 1999 classification","volume":"89","author":"Caton","year":"2018","journal-title":"J Periodontol"},{"key":"R3-20240828","doi-asserted-by":"crossref","first-page":"1758","DOI":"10.1177\/00220345000790100501","article-title":"Evidence of genetic heterogeneity for hereditary gingival fibromatosis","volume":"79","author":"Hart","year":"2000","journal-title":"J Dent Res"},{"key":"R4-20240828","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/0030-4220(94)90118-X","article-title":"Laband syndrome. 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