{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:32:43Z","timestamp":1787758363665,"version":"build-2784847793"},"reference-count":19,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>\n                      <jats:italic toggle=\"yes\">Myristica fragrans<\/jats:italic>\n                      , commonly known as nutmeg, has been shown to have many medicinal properties including reduction of plaque and oral halitosis. In the present study, a mouthwash was prepared from nutmeg oil to compare its effectiveness with 0.2% chlorhexidine (CHX) gluconate mouthwash on halitosis and plaque control.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods:<\/jats:title>\n                    <jats:p>\n                      A total of 60 participants having plaque and plaque-induced oral halitosis were enrolled and randomly divided into two groups as Group A (30) and Group B (30). Nutmeg and 0.2% CHX gluconate mouthwash were administered in Group A and Group B, respectively, for 21 days twice daily. Plaque index and organoleptic score were recorded at baseline, 14\n                      <jats:sup>th<\/jats:sup>\n                      day, and 21\n                      <jats:sup>st<\/jats:sup>\n                      day. The data were collected, tabulated in Microsoft Excel Sheet, and subjected to statistical analysis using appropriate statistical tests.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      The percentage of change in plaque score between baseline and 14\n                      <jats:sup>th<\/jats:sup>\n                      day was 12.3% and 9.44% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.741), between baseline and 21\n                      <jats:sup>st<\/jats:sup>\n                      day 39.2% and 39.4% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.889), and between 14\n                      <jats:sup>th<\/jats:sup>\n                      and 21\n                      <jats:sup>st<\/jats:sup>\n                      day 27.7% and 29.9% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.805) for Group A and Group B, respectively, while the percentage of change in halitosis score between baseline and 14\n                      <jats:sup>th<\/jats:sup>\n                      day was 24.7% and 16.3% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.201), between baseline and 21\n                      <jats:sup>st<\/jats:sup>\n                      day 54.5% and 56.3% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.487), and between 14\n                      <jats:sup>th<\/jats:sup>\n                      and 21\n                      <jats:sup>st<\/jats:sup>\n                      day 34.9% and 40.0% (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.393) for Group A and Group B, respectively.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Nutmeg mouthwash is organic, economical, and equally effective as compared to 0.2% CHX gluconate mouthwash (Clinical Trials Registry-India\/2020\/10\/028540).<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jisp.jisp_868_20","type":"journal-article","created":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T01:12:10Z","timestamp":1661476330000},"page":"384-389","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":10,"title":["Comparative evaluation of nutmeg mouthwash and 0.2% chlorhexidine gluconate mouthwash on halitosis and plaque control"],"prefix":"10.4103","volume":"26","author":[{"given":"Monika Vasantrao","family":"Padol","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashanth","family":"Vishwakarma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arun Suresh","family":"Dodamani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anup Wamanrao","family":"Gore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karina Shyamlal","family":"Chachlani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shradha Pramod","family":"Kharkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-13-20240828","doi-asserted-by":"crossref","first-page":"468","DOI":"10.1177\/2156587216679532","article-title":"Comparative evaluation of triphala and ela 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