{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T15:22:52Z","timestamp":1787757772222,"version":"build-2784847793"},"reference-count":12,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"3","content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title\/>\n                    <jats:p>Gingival enlargement may be a result of multifactorial etiology which includes local factors such as calculus, food lodgement, overhanging restorations, and overextended dentures as well as systemic conditions such as hormonal disturbances and blood dyscrasias. Acquired immune deficiency is a manifestation of immune disorder caused by a retrovirus Human Immunodeficiency Virus (HIV). The association of Acquired Immunodeficiency Syndrome or HIV with oral and periodontal lesions is highly significant. Seropositive patients usually present with periodontal diseases and atypical periodontal lesions. These clinical findings may prove to be a link for probing patients\u2019 systemic health. This case report describes one such case of a patient, unaware of HIV infection with localized gingival overgrowth, wherein detailed probing and investigation led to the diagnosis of underlying systemic condition as acquired immunodeficiency. Subsequently, antiretroviral therapy was started, and nonsurgical periodontal therapy was performed to resolve the gingival overgrowth.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jisp.jisp_886_20","type":"journal-article","created":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T23:10:37Z","timestamp":1651446637000},"page":"283-286","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":0,"title":["A curious case of gingival enlargement - From seropositive diagnosis for human immunodeficiency virus to periodontal management"],"prefix":"10.4103","volume":"26","author":[{"given":"Sonal Vasudev","family":"Kakarmath","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajesh Prabhakar","family":"Gaikwad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshaya Bhupesh","family":"Banodkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priyanka Ganpatrao","family":"Awasare","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","reference":[{"key":"R1-15-20240828","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1902\/annals.1999.4.1.1","article-title":"Development of a classification system for periodontal diseases and conditions","volume":"4","author":"Armitage","year":"1999","journal-title":"Ann Periodontol"},{"key":"R2-15-20240828","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1111\/jcpe.12646","article-title":"Prevalence of periodontal diseases in a multicentre cohort of perinatally HIV-infected and HIV-exposed and uninfected youth","volume":"44","author":"Ryder","year":"2016","journal-title":"J Clin Periodontol"},{"key":"R3-15-20240828","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/0030-4220(92)90186-T","article-title":"Periodontal disease associated with HIV infection","volume":"73","author":"Winkler","year":"1992","journal-title":"Oral Surg Oral Med Oral Pathol"},{"key":"R4-15-20240828","first-page":"1","article-title":"Guidelines for performing single-platform absolute CD4+ T-cell determinations with CD45 gating for persons infected with human immunodeficiency virus. 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