{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T20:20:39Z","timestamp":1787775639986,"version":"build-2784847793"},"reference-count":18,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2022,10,1]],"date-time":"2022-10-01T00:00:00Z","timestamp":1664582400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2022,10]]},"abstract":"ABSTRACT<\/jats:title>\n \n Background:<\/jats:title>\n To overcome some of the disadvantages of the current primary root canal obturating materials, there is a continued interest in search for chemical compounds with broader and more effective antibacterial action and less cytotoxicity.<\/jats:p>\n <\/jats:sec>\n \n Aim:<\/jats:title>\n \n This study aimed to evaluate and compare\n in vivo<\/jats:italic>\n the clinical and radiographic success of mixtures of zinc oxide\u2013\n Ocimum<\/jats:italic>\n sanctum<\/jats:italic>\n extract, zinc oxide\u2013ozonated oil, and zinc oxide\u2013eugenol (ZOE) as obturating materials in pulpectomy of primary molars.\n <\/jats:p>\n <\/jats:sec>\n \n Settings and Design:<\/jats:title>\n \n This was an\n in vivo<\/jats:italic>\n randomized controlled clinical trial.\n <\/jats:p>\n <\/jats:sec>\n \n Materials and Methods:<\/jats:title>\n \n Ninety primary molars selected were randomly divided into three groups. Group A was obturated with zinc oxide\u2013\n O<\/jats:italic>\n .\n sanctum<\/jats:italic>\n extract, Group B with zinc oxide\u2013ozonated oil, and Group C with ZOE. All the groups were evaluated for success or failure based on clinical and radiographic criteria at the end of 1, 6, and 12 months.\n <\/jats:p>\n <\/jats:sec>\n \n Statistical Analysis Used:<\/jats:title>\n \n The intra- and inter-examiner reliability of the first and the second co-investigators was calculated by Cohen\u2019s kappa statistic. The data were analyzed using Chi-square test,\n P \u2264<\/jats:italic>\n 0.05 (indicates statistical significance).\n <\/jats:p>\n <\/jats:sec>\n \n Results:<\/jats:title>\n By the end of 12 months, the overall clinical success rate was 88%, 95.7%, and 90.9% in Groups A, B, and C, respectively; whereas the radiographic success rate was found to be 80%, 91.3%, and 86.4% in Groups A, B, and C, respectively.<\/jats:p>\n <\/jats:sec>\n \n Conclusion:<\/jats:title>\n \n On the basis of the overall success rates of all the three obturating materials, the following order of performance can be concluded: zinc oxide\u2013ozonated oil > ZOE > zinc oxide\u2013\n O<\/jats:italic>\n .\n sanctum<\/jats:italic>\n extract.\n <\/jats:p>\n <\/jats:sec>","DOI":"10.4103\/jisppd.jisppd_204_22","type":"journal-article","created":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T05:27:33Z","timestamp":1716269253000},"page":"398-403","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":4,"title":["An in vivo comparative clinical and radiographic evaluation of a mixture of zinc oxide\u2013Ocimum sanctum extract, zinc oxide\u2013ozonated oil, and zinc oxide\u2013eugenol as obturating materials in primary molars"],"prefix":"10.4103","volume":"40","author":[{"given":"Krishnaben","family":"Vachhani","sequence":"first","affiliation":[{"name":"Department of Paediatric Dentistry, Pacific Dental College and Hospital, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dinesh","family":"Rao","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry, Pacific Dental College and Hospital, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunil","family":"Panwar","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry, Pacific Dental College and Hospital, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Surabhi","family":"Gupta","sequence":"additional","affiliation":[{"name":"Department of Paediatric Dentistry, Pacific Dental College and Hospital, Udaipur, Rajasthan, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2023,2,23]]},"reference":[{"key":"R1-20260803","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1111\/iej.12478","article-title":"Pulpectomies in primary mandibular molars:A comparison of outcomes using three root filling materials","volume":"49","author":"Pramila","year":"2016","journal-title":"Int Endod J"},{"key":"R2-20260803","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/0030-4220(92)90020-Q","article-title":"Biologic properties of eugenol and zinc oxide-eugenol. 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