{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T14:18:01Z","timestamp":1793110681742,"version":"4.5.0"},"reference-count":32,"publisher":"Ovid Technologies (Wolters Kluwer Health)","issue":"4","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":["lww.com","ovid.com"],"crossmark-restriction":true},"short-container-title":[],"published-print":{"date-parts":[[2024,10]]},"abstract":"<jats:title>ABSTRACT<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>Smart burs and chemo-mechanical caries removal (CMCR) systems are considered viable alternatives to traditional cavity preparation techniques. Numerous clinical studies have been conducted to assess and compare the impact of these two techniques; nevertheless, these studies have demonstrated considerable variability in their findings. The objectives of the present systematic review and meta-analysis were to compare the efficacy, efficiency, and patient comfort of CMCR systems and smart burs in primary molars.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methodology:<\/jats:title>\n                    <jats:p>\n                      The review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analysis 2020 guidelines. Ten electronic databases up to May 30, 2024 were searched for\n                      <jats:italic toggle=\"yes\">in vivo<\/jats:italic>\n                      clinical studies comparing at least one CMCR system with smart burs in terms of clinical and\/or microbiological efficacy, efficiency (time taken for complete caries removal), and patient comfort in primary molars. Reviews, abstracts, case series and reports, letters to the editor, animal studies, and unpublished data were excluded. The risk of bias (ROB) assessment was conducted using the ROBINS-I and Cochrane ROB tools for nonrandomized and randomized clinical studies, respectively. The analysis was performed using Review Manager version 5.4.1 provided by the Cochrane Collaboration. The standardized mean difference served as the summary with a random effects model (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 154 studies were identified and screened out of which five were included in the qualitative synthesis and four studies were deemed suitable for a meta-analysis. The overall quality assessment revealed a presence of moderate-to-low ROB. The data extracted from the five studies were tabulated. The summary odds ratio for clinical efficacy (0.43 [95% confidence interval (CI) = 0.13\u20131.49]) showed no statistically significant difference between CMCR systems and Smart burs (Z = 1.33 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.18). A statistically significant difference ([Z = 5.85 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.00001] and [Z = 2.84 and\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.005]) in terms of microbiological efficacy (446.46 [95% CI = 296.89\u2013596.02]) and efficiency (\u22120.68 [95% CI = \u22121.16\u2013\u22120.21]) was observed between CMCR systems and smart burs. Smart burs performed better in terms of microbiological efficacy and efficiency. Due to variability in the scales used to evaluate patient comfort, meta-analysis was not possible.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Within the limitations of this study, Smart burs performed better in terms of microbiological efficacy and efficiency and hence can be used as an alternative to CMCR systems in primary molars.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.4103\/jisppd.jisppd_308_24","type":"journal-article","created":{"date-parts":[[2025,1,11]],"date-time":"2025-01-11T13:00:21Z","timestamp":1736600421000},"page":"257-266","update-policy":"https:\/\/doi.org\/10.1097\/lww.0000000000001000","source":"Crossref","is-referenced-by-count":3,"title":["Comparison of smart burs and chemo-mechanical caries removal systems in primary molars \u2013 A systematic review and meta-analysis"],"prefix":"10.4103","volume":"42","author":[{"given":"Deepshikha","family":"Mehrotra","sequence":"first","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, D. Y. Patil University School of Dentistry, Navi Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjana R.","family":"Kodical","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, D. Y. Patil University School of Dentistry, Navi Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shilpa Shetty","family":"Naik","sequence":"additional","affiliation":[{"name":"Department of Pediatric and Preventive Dentistry, D. Y. Patil University School of Dentistry, Navi Mumbai, Maharashtra, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"276","published-online":{"date-parts":[[2025,1,11]]},"reference":[{"key":"R1-20250111","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1177\/0022034519837252","article-title":"A century of change towards prevention and minimal intervention in cariology","volume":"98","author":"Innes","year":"2019","journal-title":"J Dent Res"},{"key":"R2-20250111","doi-asserted-by":"crossref","first-page":"3407","DOI":"10.3390\/jcm9113407","article-title":"Efficacy and patient's acceptance of alternative methods for caries removal-a systematic review","volume":"9","author":"Cardoso","year":"2020","journal-title":"J Clin Med"},{"key":"R3-20250111","doi-asserted-by":"crossref","first-page":"134","DOI":"10.4103\/JCDE.JCDE_274_23","article-title":"Minimal intervention dentistry:What is its clinical application and effectiveness in different continents?A scoping review","volume":"27","author":"Perrone","year":"2024","journal-title":"J Conserv Dent Endod"},{"key":"R4-20250111","doi-asserted-by":"crossref","first-page":"163","DOI":"10.4103\/JCD.JCD_269_20","article-title":"Comparative evaluation of BRIX3000, CARIE CARE, and SMART BURS in caries excavation:An in vivo study","volume":"23","author":"Inamdar","year":"2020","journal-title":"J Conserv Dent"},{"key":"R5-20250111","first-page":"12","article-title":"Comparative evaluation of efficiency, efficacy, and patient perception of caries excavation burs in pediatric patients:A randomized clinical trial","volume":"5","author":"Goyal","year":"2022","journal-title":"J South Asian Assoc Pediatr Dent"},{"key":"R6-20250111","doi-asserted-by":"crossref","first-page":"103280","DOI":"10.1016\/j.jdent.2020.103280","article-title":"Comparing the efficacies of two chemo-mechanical caries removal agents (2.25% sodium hypochlorite gel and brix 3000), in caries removal and patient cooperation:A randomized controlled clinical trial","volume":"93","author":"Alkhouli","year":"2020","journal-title":"J Dent"},{"key":"R7-20250111","doi-asserted-by":"crossref","first-page":"E167","DOI":"10.2341\/14-021-LIT","article-title":"Systematic review and meta-analysis of randomized clinical trials on chemomechanical caries removal","volume":"40","author":"Hamama","year":"2015","journal-title":"Oper Dent"},{"key":"R8-20250111","doi-asserted-by":"crossref","first-page":"266","DOI":"10.7126\/cumudj.920058","article-title":"Comparison of two aerosol-free caries removal methods:A split-mouth randomized clinical trial","volume":"24","author":"Duman","year":"2021","journal-title":"Cumhuriyet Dent J"},{"key":"R9-20250111","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/s40368-014-0140-1","article-title":"A comparative clinical study of various methods of caries removal in children","volume":"16","author":"Soni","year":"2015","journal-title":"Eur Arch Paediatr Dent"},{"key":"R10-20250111","first-page":"444","article-title":"Evaluation of the efficacy of caries removal using papain gel (Brix 3000) and smart preparation bur (in vivo comparative study)","volume":"11","author":"Ismail","year":"2019","journal-title":"J Pharm Sci Res"},{"key":"R12-20250111","doi-asserted-by":"crossref","first-page":"n71","DOI":"10.1136\/bmj.n71","article-title":"The PRISMA 2020 statement:An updated guideline for reporting systematic reviews","volume":"372","author":"Page","year":"2021","journal-title":"BMJ"},{"key":"R13-20250111","doi-asserted-by":"crossref","first-page":"i4919","DOI":"10.1136\/bmj.i4919","article-title":"ROBINS-I:A tool for assessing risk of bias in non-randomised studies of interventions","volume":"355","author":"Sterne","year":"2016","journal-title":"BMJ"},{"key":"R14-20250111","doi-asserted-by":"crossref","first-page":"l4898","DOI":"10.1136\/bmj.l4898","article-title":"RoB 2:A revised tool for assessing risk of bias in randomised trials","volume":"366","author":"Sterne","year":"2019","journal-title":"BMJ"},{"key":"R15-20250111","article-title":"Review Manager (RevMan) \u2013Computer Program. Ver. 5.3","year":"2012","journal-title":"Copenhagen:The Nordic Cochrane Centre"},{"key":"R16-20250111","doi-asserted-by":"crossref","first-page":"357","DOI":"10.5005\/jp-journals-10005-1956","article-title":"Clinical and microbiological assessment of carisolv and polymer bur for selective caries removal in primary molars","volume":"14","author":"Asal","year":"2021","journal-title":"Int J Clin Pediatr Dent"},{"key":"R17-20250111","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4103\/2393-8692.184732","article-title":"Clinical evaluation of caries removal in primary teeth using carie-care and SmartPrep burs:An in vivo study","volume":"2","author":"Shivasharan","year":"2016","journal-title":"Indian J Oral Health Res"},{"key":"R18-20250111","doi-asserted-by":"crossref","first-page":"3516","DOI":"10.53730\/ijhs.v6nS8.12882","article-title":"Comparative evaluation of microhardness of residual dentin in primary molars following caries removal with chemomechanical agent (BRIX 3000) and polymer burs (ss white): In vitro study","volume":"6","author":"Gunjal","year":"2022","journal-title":"Int J Health Sci"},{"key":"R19-20250111","doi-asserted-by":"crossref","first-page":"6","DOI":"10.4103\/0970-4388.199232","article-title":"Comparison of efficacy of caries removal using polymer bur and chemomechanical caries removal agent:A clinical and microbiological assessment \u2013An in vivo study","volume":"35","author":"Aswathi","year":"2017","journal-title":"J Indian Soc Pedod Prev Dent"},{"key":"R20-20250111","doi-asserted-by":"crossref","first-page":"386","DOI":"10.4103\/1305-7456.184151","article-title":"Chemomechanical caries removal method versus mechanical caries removal methods in clinical and community-based setting:A comparative in vivo study","volume":"10","author":"Kumar","year":"2016","journal-title":"Eur J Dent"},{"key":"R21-20250111","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1159\/000016513","article-title":"Clinical evaluation of efficacy and safety of a new method for chemo-mechanical removal of caries. A multi-centre study","volume":"33","author":"Ericson","year":"1999","journal-title":"Caries Res"},{"key":"R22-20250111","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1038\/s41415-023-5515-4","article-title":"Minimally invasive selective caries removal:A clinical guide","volume":"234","author":"Lim","year":"2023","journal-title":"Br Dent J"},{"key":"R23-20250111","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1177\/0022034516639271","article-title":"Managing carious lesions:Consensus recommendations on carious tissue removal","volume":"28","author":"Schwendicke","year":"2016","journal-title":"Adv Dent Res"},{"key":"R24-20250111","first-page":"CD014546","article-title":"Visual or visual-tactile examination to detect and inform the diagnosis of enamel caries","volume":"6","author":"Macey","year":"2021","journal-title":"Cochrane Database Syst Rev"},{"key":"R25-20250111","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1159\/000261571","article-title":"Microbiological validation of assessments of caries activity during cavity preparation","volume":"27","author":"Kidd","year":"1993","journal-title":"Caries Res"},{"key":"R26-20250111","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.sdentj.2023.01.010","article-title":"Chemomechanical caries removal methods:A literature review","volume":"35","author":"Maashi","year":"2023","journal-title":"Saudi Dent J"},{"key":"R27-20250111","doi-asserted-by":"crossref","first-page":"256","DOI":"10.2341\/05-24","article-title":"Efficiency of the polymer bur SmartPrep compared with conventional tungsten carbide bud bur in dentin caries excavation","volume":"31","author":"Dammaschke","year":"2006","journal-title":"Oper Dent"},{"key":"R28-20250111","first-page":"77","article-title":"An evaluation of polymer rotary instruments'ability to remove healthy, non-carious dentine","volume":"15","author":"Hauman","year":"2007","journal-title":"Eur J Prosthodont Restor Dent"},{"key":"R29-20250111","doi-asserted-by":"crossref","first-page":"583","DOI":"10.2334\/josnusd.16-0225","article-title":"Histological evaluation of three techniques for caries removal","volume":"58","author":"Medioni","year":"2016","journal-title":"J Oral Sci"},{"key":"R30-20250111","doi-asserted-by":"crossref","first-page":"462","DOI":"10.2174\/1874210601509010462","article-title":"Caries removal by chemomechanical (Carisolv\u2122) versus Rotary Drill:A systematic review","volume":"9","author":"Maru","year":"2015","journal-title":"Open Dent J"},{"key":"R31-20250111","doi-asserted-by":"crossref","first-page":"2937","DOI":"10.3390\/jcm11102937","article-title":"Diagnostic validity in occlusal caries detection of ICDAS II, DIAGNOdent, radiography and a combination of the three methods:An in vitro study","volume":"11","author":"Minuesa-Garc\u00eda","year":"2022","journal-title":"J Clin Med"},{"key":"R32-20250111","doi-asserted-by":"crossref","first-page":"232","DOI":"10.3390\/dj11100232","article-title":"Use of digital diagnostic aids for initial caries detection:A review","volume":"11","author":"Chan","year":"2023","journal-title":"Dent J (Basel)"},{"key":"R33-20250111","first-page":"195","article-title":"Caries-detector dyes \u2013How accurate and useful are they?","volume":"66","author":"McComb","year":"2000","journal-title":"J Can Dent Assoc"}],"container-title":["Journal of Indian Society of Pedodontics and Preventive Dentistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.ovid.com\/10.4103\/jisppd.jisppd_308_24","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T19:41:53Z","timestamp":1787773313000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.ovid.com\/10.4103\/jisppd.jisppd_308_24"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":32,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024]]}},"URL":"https:\/\/doi.org\/10.4103\/jisppd.jisppd_308_24","relation":{},"ISSN":["0970-4388","1998-3905"],"issn-type":[{"value":"0970-4388","type":"print"},{"value":"1998-3905","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"2024-07-25","name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-06","name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}}]}}