{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T03:51:32Z","timestamp":1791690692247,"version":"4.3.4"},"reference-count":26,"publisher":"Scientific Scholar","issue":"03","license":[{"start":{"date-parts":[[2020,2,19]],"date-time":"2020-02-19T00:00:00Z","timestamp":1582070400000},"content-version":"vor","delay-in-days":598,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Lab Physicians"],"published-print":{"date-parts":[[2018,7]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>\n          PURPOSE: Bloodstream infection can range from inapparent bacteremia until fulminant septic shock with high mortality. Microorganisms present in circulating blood whether continuously, intermittently, or transiently are a threat to every organ in the body. Culture of blood is a vital tool to diagnose such infections. Drug susceptibility patterns help in rationalizing therapy.<\/jats:p><jats:p>\n          OBJECTIVE: The objective of this study was to perform bacteriological analysis and assess drug sensitivity patterns of isolates from blood stream infections.<\/jats:p><jats:p>\n          DESIGN: Retrospective observational study was conducted from May 2015 to February 2017 at a tertiary care hospital, Port Blair, India. Blood samples were collected with aseptic guidelines and cultured for 7 days. Growths were identified using standard biochemical tests and subjected to sensitivity testing according to Modified Kirby\u2013Bauer\u2019s disk diffusion method. Data for the source of blood collection and duration of incubation were noted and compared.<\/jats:p><jats:p>\n          RESULTS: A total of 270 (14.24%) pathogens were isolated from 1895 bacteremia suspect patient blood specimens. Contamination was observed at a rate of 1.63%. Gram-positive cocci (60.37%) were predominant organisms recovered followed by Gram-negative Bacilli (36.29%) and Yeasts (3.33%). Staphylococcus aureus, CoNS, and Acinetobacter spp. were the primary pathogens isolated. Aminoglycosides, carbapenems, and glycopeptides were the most effective drugs for treating bacteremia.<\/jats:p><jats:p>\n          CONCLUSIONS: Successful treatment of sepsis depends on early diagnosis and proper antimicrobial therapy. Local knowledge of bacteriological profile and antimicrobial sensitivity patterns helps rationalize empiric treatment strategies.<\/jats:p>","DOI":"10.4103\/jlp.jlp_50_18","type":"journal-article","created":{"date-parts":[[2018,7,6]],"date-time":"2018-07-06T05:03:48Z","timestamp":1530853428000},"page":"332-337","source":"Crossref","is-referenced-by-count":31,"title":["Bloodstream infections and trends of antimicrobial sensitivity patterns at Port Blair"],"prefix":"10.25259","volume":"10","author":[{"given":"Amit","family":"Banik","sequence":"additional","affiliation":[{"name":"Department of Microbiology, All India Institute of Hygiene and Public Health, Kolkata, West Bengal, India,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjeev H.","family":"Bhat","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhay","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnijeet","family":"Palit","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kandregula","family":"Snehaa","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, Andaman and Nicobar Islands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"10894","published-online":{"date-parts":[[2020,2,19]]},"reference":[{"key":"key-10.4103\/0974-2727.236114-1","first-page":"119","volume-title":"Bloodstream infections and antimicrobial sensitivity patterns in a tertiary care hospital of India","author":"Vasudeva","year":"2016","journal-title":"Ther Adv Infect Dis"},{"key":"key-10.4103\/0974-2727.236114-2","unstructured":"Seifert H, Wisplinghoff H. Bloodstream infection and endocarditis. In: Borriello SP, Murray PR, Funke G, editors. Topley and Wilson's Microbiology and Microbial Infections, Bacteriology. 10th ed., Vol. 1. Ch. 4.1. London: Hodder Arnold ASM Press; 2005. p. 1181-235."},{"key":"key-10.4103\/0974-2727.236114-3","unstructured":"CLSI. Principles and Procedures for Blood Cultures; approved Guideline. CLSI Document M47-A. Wayne, PA: Clinical and Laboratory Standards Institute; 2017."},{"key":"key-10.4103\/0974-2727.236114-4","unstructured":"Clinical and Laboratory Standards Institute. Performance Standards for Antimicrobial Susceptibility Testing: Twenty- Fourth Informational Supplement. CLSI Document M100-S27. Wayne, PA: Clinical and Laboratory Standards Institute; 2017."},{"key":"key-10.4103\/0974-2727.236114-5","unstructured":"Clinical and Laboratory Standards Institute. Method for Antifungal disc Diffusion Susceptibility Testing of Yeast; approved Guideline. CLSI Document M44-A2. 2nd ed. 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